JPS5657753A - Novel glucagon fragment, and its use - Google Patents
Novel glucagon fragment, and its useInfo
- Publication number
- JPS5657753A JPS5657753A JP13406179A JP13406179A JPS5657753A JP S5657753 A JPS5657753 A JP S5657753A JP 13406179 A JP13406179 A JP 13406179A JP 13406179 A JP13406179 A JP 13406179A JP S5657753 A JPS5657753 A JP S5657753A
- Authority
- JP
- Japan
- Prior art keywords
- bonding
- formula
- hapten
- pref
- gln
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical group C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
- 102400000321 Glucagon Human genes 0.000 abstract 1
- 108060003199 Glucagon Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 229960004666 glucagon Drugs 0.000 abstract 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
- 230000008105 immune reaction Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000006340 racemization Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13406179A JPS5657753A (en) | 1979-10-16 | 1979-10-16 | Novel glucagon fragment, and its use |
| SE8007074A SE8007074L (sv) | 1979-10-16 | 1980-10-09 | Glukagonfragment jemte dess anvendning |
| FR8021924A FR2467841A1 (fr) | 1979-10-16 | 1980-10-14 | Fragment de glucagon et son application a la preparation d'un anticorps specifique |
| GB8033248A GB2062644B (en) | 1979-10-16 | 1980-10-15 | Glucagon fragment and utility thereof |
| DE19803039122 DE3039122A1 (de) | 1979-10-16 | 1980-10-16 | Glucagonfragment und seine verwendung |
| NL8005703A NL8005703A (nl) | 1979-10-16 | 1980-10-16 | Glucagonfragment en zijn toepassing. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13406179A JPS5657753A (en) | 1979-10-16 | 1979-10-16 | Novel glucagon fragment, and its use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14873280A Division JPS5681450A (en) | 1980-10-23 | 1980-10-23 | Determination method for glucagon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5657753A true JPS5657753A (en) | 1981-05-20 |
Family
ID=15119442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13406179A Pending JPS5657753A (en) | 1979-10-16 | 1979-10-16 | Novel glucagon fragment, and its use |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5657753A (OSRAM) |
| DE (1) | DE3039122A1 (OSRAM) |
| FR (1) | FR2467841A1 (OSRAM) |
| GB (1) | GB2062644B (OSRAM) |
| NL (1) | NL8005703A (OSRAM) |
| SE (1) | SE8007074L (OSRAM) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5835157A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトリムホブラストイドインターフェロンのｎ末端ペプチド |
| JPS5835155A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトリムホブラストイドインターフェロンのｃ末端ペプチド |
| JPS5835125A (ja) * | 1982-03-26 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトα型インタ−フエロン抗体の製造法 |
| JPS5835156A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 螢光標識ペプチド及びそれを利用するヒトβ型インタ−フエロンの測定法 |
| JPS5835124A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 抗体の製造法 |
| JPS5835123A (ja) * | 1982-03-26 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトα型インタ−フエロン抗原の製造法 |
| JPS5835122A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 抗原の製造法 |
| JPS59122446A (ja) * | 1982-12-28 | 1984-07-14 | Otsuka Pharmaceut Co Ltd | γ−インタ−フエロン関連ペプチド |
| JPS60120824A (ja) * | 1983-08-17 | 1985-06-28 | ザ ウエルカム フアウンデ−シヨン リミテツド | ホルモン活性処方物 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK283180A (da) * | 1980-07-01 | 1982-01-02 | Novo Industri As | Polypeptider og derivater deraf |
| GB2160312B (en) * | 1984-04-13 | 1987-09-16 | South African Inventions | Adjuvant for immunisation |
| DE9319125U1 (de) * | 1993-12-13 | 1994-02-24 | Bulldog Beratungs- und Vertriebsgesellschaft mbH, 28857 Syke | Verbindungselement zum Verbinden eines Holzbauteils mit einem zweiten Bauteil |
| WO2019197313A1 (en) | 2018-04-09 | 2019-10-17 | Svar Life Science Ab | Glucagon Assay |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3642763A (en) * | 1967-08-19 | 1972-02-15 | Hoechst Ag | Protected glucagon and its hydrobromide salts |
| JPS5424868A (en) * | 1977-07-22 | 1979-02-24 | Takeda Chem Ind Ltd | Novel glucagon fragment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5836308B2 (ja) * | 1977-02-10 | 1983-08-08 | 大塚製薬株式会社 | 抗体の製造方法 |
| US4206199A (en) * | 1977-07-22 | 1980-06-03 | Takeda Chemical Industries, Ltd. | Novel glucagon fragment and its derivatives |
| JPS5539702A (en) * | 1978-08-30 | 1980-03-19 | Takeda Chem Ind Ltd | Method of measuring enzyme immunity of pancreas glucagon |
-
1979
- 1979-10-16 JP JP13406179A patent/JPS5657753A/ja active Pending
-
1980
- 1980-10-09 SE SE8007074A patent/SE8007074L/ not_active Application Discontinuation
- 1980-10-14 FR FR8021924A patent/FR2467841A1/fr active Granted
- 1980-10-15 GB GB8033248A patent/GB2062644B/en not_active Expired
- 1980-10-16 NL NL8005703A patent/NL8005703A/nl not_active Application Discontinuation
- 1980-10-16 DE DE19803039122 patent/DE3039122A1/de not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3642763A (en) * | 1967-08-19 | 1972-02-15 | Hoechst Ag | Protected glucagon and its hydrobromide salts |
| JPS5424868A (en) * | 1977-07-22 | 1979-02-24 | Takeda Chem Ind Ltd | Novel glucagon fragment |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5835157A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトリムホブラストイドインターフェロンのｎ末端ペプチド |
| JPS5835155A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトリムホブラストイドインターフェロンのｃ末端ペプチド |
| JPS5835156A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 螢光標識ペプチド及びそれを利用するヒトβ型インタ−フエロンの測定法 |
| JPS5835124A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 抗体の製造法 |
| JPS5835122A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 抗原の製造法 |
| JPS5835125A (ja) * | 1982-03-26 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトα型インタ−フエロン抗体の製造法 |
| JPS5835123A (ja) * | 1982-03-26 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトα型インタ−フエロン抗原の製造法 |
| JPS59122446A (ja) * | 1982-12-28 | 1984-07-14 | Otsuka Pharmaceut Co Ltd | γ−インタ−フエロン関連ペプチド |
| JPS60120824A (ja) * | 1983-08-17 | 1985-06-28 | ザ ウエルカム フアウンデ−シヨン リミテツド | ホルモン活性処方物 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL8005703A (nl) | 1981-04-22 |
| SE8007074L (sv) | 1981-04-17 |
| GB2062644B (en) | 1983-04-07 |
| FR2467841B1 (OSRAM) | 1984-10-19 |
| DE3039122A1 (de) | 1981-04-30 |
| GB2062644A (en) | 1981-05-28 |
| FR2467841A1 (fr) | 1981-04-30 |
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