NL8005703A - Glucagonfragment en zijn toepassing. - Google Patents
Glucagonfragment en zijn toepassing. Download PDFInfo
- Publication number
- NL8005703A NL8005703A NL8005703A NL8005703A NL8005703A NL 8005703 A NL8005703 A NL 8005703A NL 8005703 A NL8005703 A NL 8005703A NL 8005703 A NL8005703 A NL 8005703A NL 8005703 A NL8005703 A NL 8005703A
- Authority
- NL
- Netherlands
- Prior art keywords
- glucagon
- group
- arg
- bsa
- gln
- Prior art date
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- 150000002170 ethers Chemical group 0.000 description 1
- CHDFNIZLAAFFPX-UHFFFAOYSA-N ethoxyethane;oxolane Chemical compound CCOCC.C1CCOC1 CHDFNIZLAAFFPX-UHFFFAOYSA-N 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 description 1
- 108010018006 histidylserine Proteins 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 238000006698 hydrazinolysis reaction Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- NPZTUJOABDZTLV-UHFFFAOYSA-N hydroxybenzotriazole Substances O=C1C=CC=C2NNN=C12 NPZTUJOABDZTLV-UHFFFAOYSA-N 0.000 description 1
- JBFYUZGYRGXSFL-UHFFFAOYSA-N imidazolide Chemical compound C1=C[N-]C=N1 JBFYUZGYRGXSFL-UHFFFAOYSA-N 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 230000009851 immunogenic response Effects 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 229960003136 leucine Drugs 0.000 description 1
- 108010091871 leucylmethionine Proteins 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000008176 lyophilized powder Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229960004452 methionine Drugs 0.000 description 1
- UZKWTJUDCOPSNM-UHFFFAOYSA-N methoxybenzene Substances CCCCOC=C UZKWTJUDCOPSNM-UHFFFAOYSA-N 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229960005190 phenylalanine Drugs 0.000 description 1
- 239000008055 phosphate buffer solution Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000006340 racemization Effects 0.000 description 1
- 238000006722 reduction reaction Methods 0.000 description 1
- 235000004400 serine Nutrition 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- ZFRKQXVRDFCRJG-UHFFFAOYSA-N skatole Chemical compound C1=CC=C2C(C)=CNC2=C1 ZFRKQXVRDFCRJG-UHFFFAOYSA-N 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 235000008521 threonine Nutrition 0.000 description 1
- 229960004799 tryptophan Drugs 0.000 description 1
- 229960004295 valine Drugs 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13406179 | 1979-10-16 | ||
| JP13406179A JPS5657753A (en) | 1979-10-16 | 1979-10-16 | Novel glucagon fragment, and its use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8005703A true NL8005703A (nl) | 1981-04-22 |
Family
ID=15119442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8005703A NL8005703A (nl) | 1979-10-16 | 1980-10-16 | Glucagonfragment en zijn toepassing. |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5657753A (OSRAM) |
| DE (1) | DE3039122A1 (OSRAM) |
| FR (1) | FR2467841A1 (OSRAM) |
| GB (1) | GB2062644B (OSRAM) |
| NL (1) | NL8005703A (OSRAM) |
| SE (1) | SE8007074L (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK283180A (da) * | 1980-07-01 | 1982-01-02 | Novo Industri As | Polypeptider og derivater deraf |
| JPS5835156A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 螢光標識ペプチド及びそれを利用するヒトβ型インタ−フエロンの測定法 |
| JPS5835155A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトリムホブラストイドインターフェロンのｃ末端ペプチド |
| JPS5835157A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトリムホブラストイドインターフェロンのｎ末端ペプチド |
| JPS5835122A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 抗原の製造法 |
| JPS5835124A (ja) * | 1981-08-24 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | 抗体の製造法 |
| JPS5835125A (ja) * | 1982-03-26 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトα型インタ−フエロン抗体の製造法 |
| JPS5835123A (ja) * | 1982-03-26 | 1983-03-01 | Otsuka Pharmaceut Co Ltd | ヒトα型インタ−フエロン抗原の製造法 |
| JPS59122446A (ja) * | 1982-12-28 | 1984-07-14 | Otsuka Pharmaceut Co Ltd | γ−インタ−フエロン関連ペプチド |
| GB8322115D0 (en) * | 1983-08-17 | 1983-09-21 | Wellcome Found | Physiologically active compositions |
| GB2160312B (en) * | 1984-04-13 | 1987-09-16 | South African Inventions | Adjuvant for immunisation |
| DE9319125U1 (de) * | 1993-12-13 | 1994-02-24 | Bulldog Beratungs- und Vertriebsgesellschaft mbH, 28857 Syke | Verbindungselement zum Verbinden eines Holzbauteils mit einem zweiten Bauteil |
| WO2019197313A1 (en) | 2018-04-09 | 2019-10-17 | Svar Life Science Ab | Glucagon Assay |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1643345C3 (de) * | 1967-08-19 | 1975-09-25 | Hoechst Ag, 6000 Frankfurt | Glucagonderivat und Verfahren zur Herstellung von Glucagon |
| JPS5836308B2 (ja) * | 1977-02-10 | 1983-08-08 | 大塚製薬株式会社 | 抗体の製造方法 |
| JPS5424868A (en) * | 1977-07-22 | 1979-02-24 | Takeda Chem Ind Ltd | Novel glucagon fragment |
| US4206199A (en) * | 1977-07-22 | 1980-06-03 | Takeda Chemical Industries, Ltd. | Novel glucagon fragment and its derivatives |
| JPS5539702A (en) * | 1978-08-30 | 1980-03-19 | Takeda Chem Ind Ltd | Method of measuring enzyme immunity of pancreas glucagon |
-
1979
- 1979-10-16 JP JP13406179A patent/JPS5657753A/ja active Pending
-
1980
- 1980-10-09 SE SE8007074A patent/SE8007074L/ not_active Application Discontinuation
- 1980-10-14 FR FR8021924A patent/FR2467841A1/fr active Granted
- 1980-10-15 GB GB8033248A patent/GB2062644B/en not_active Expired
- 1980-10-16 NL NL8005703A patent/NL8005703A/nl not_active Application Discontinuation
- 1980-10-16 DE DE19803039122 patent/DE3039122A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| SE8007074L (sv) | 1981-04-17 |
| GB2062644B (en) | 1983-04-07 |
| FR2467841B1 (OSRAM) | 1984-10-19 |
| DE3039122A1 (de) | 1981-04-30 |
| GB2062644A (en) | 1981-05-28 |
| FR2467841A1 (fr) | 1981-04-30 |
| JPS5657753A (en) | 1981-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BV | The patent application has lapsed |