ATE19792T1 - Verfahren zur herstellung eines kolonspezifischen antigen p tryptischen peptides und von anti-kolon-spezifischen antigen p antikoerpern. - Google Patents
Verfahren zur herstellung eines kolonspezifischen antigen p tryptischen peptides und von anti-kolon-spezifischen antigen p antikoerpern.Info
- Publication number
- ATE19792T1 ATE19792T1 AT82104604T AT82104604T ATE19792T1 AT E19792 T1 ATE19792 T1 AT E19792T1 AT 82104604 T AT82104604 T AT 82104604T AT 82104604 T AT82104604 T AT 82104604T AT E19792 T1 ATE19792 T1 AT E19792T1
- Authority
- AT
- Austria
- Prior art keywords
- colon
- specific antigen
- antibodies
- tryptic peptide
- production
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 230000029087 digestion Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/269,115 US4468457A (en) | 1981-06-01 | 1981-06-01 | Method for producing a CSAp tryptic peptide and anti-CSAp antibodies |
| EP82104604A EP0066786B1 (de) | 1981-06-01 | 1982-05-27 | Verfahren zur Herstellung eines Kolon-spezifischen Antigen P tryptischen Peptides und von anti-Kolon-spezifischen Antigen P Antikörpern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE19792T1 true ATE19792T1 (de) | 1986-05-15 |
Family
ID=23025864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82104604T ATE19792T1 (de) | 1981-06-01 | 1982-05-27 | Verfahren zur herstellung eines kolonspezifischen antigen p tryptischen peptides und von anti-kolon-spezifischen antigen p antikoerpern. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4468457A (de) |
| EP (1) | EP0066786B1 (de) |
| JP (1) | JPS58501355A (de) |
| AT (1) | ATE19792T1 (de) |
| AU (1) | AU550306B2 (de) |
| CA (1) | CA1183451A (de) |
| DE (1) | DE3271119D1 (de) |
| IL (1) | IL65915A (de) |
| WO (1) | WO1982004263A1 (de) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4472509A (en) * | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
| US4454106A (en) * | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
| DE3432714A1 (de) * | 1984-09-06 | 1986-04-24 | Behringwerke Ag, 3550 Marburg | Tumortherapeutikum und verfahren zu seiner herstellung |
| US4962187A (en) * | 1984-11-28 | 1990-10-09 | Cota Biotech | Common antigen for colorectal and mucinous ovarian tumors and process for isolating the same |
| NO861491L (no) * | 1985-04-22 | 1986-10-23 | Hybritech Inc | Antistoff, fremgangsmaate for dets fremstilling og anvendelse for deteksjon og diagnose av canser. |
| ES8800604A1 (es) * | 1985-04-22 | 1987-11-16 | Hybritech Inc | Un metodo para producir anticuerpos monoclonales |
| US5776093A (en) * | 1985-07-05 | 1998-07-07 | Immunomedics, Inc. | Method for imaging and treating organs and tissues |
| DK169987D0 (da) * | 1987-04-03 | 1987-04-03 | Jens Christian Jensenius | Human tumor-associated antigen, ca-ou1 |
| CA1329119C (en) * | 1988-03-29 | 1994-05-03 | Milton David Goldenberg | Cytotoxic therapy |
| ATE303160T1 (de) * | 1993-08-11 | 2005-09-15 | Jenner Technologies | Impfstoff gegen prostatakrebs |
| US7011812B1 (en) * | 1996-05-03 | 2006-03-14 | Immunomedics, Inc. | Targeted combination immunotherapy of cancer and infectious diseases |
| US6759243B2 (en) | 1998-01-20 | 2004-07-06 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
| DE69942565D1 (de) | 1998-05-20 | 2010-08-19 | Immunomedics Inc | Therapeutische mittel welche einen bispezifischen anti-hla class ii invariant chain x anti-pathogen antikörper enthalten |
| US7405320B2 (en) | 1998-06-22 | 2008-07-29 | Immunomedics, Inc. | Therapeutic and diagnostic conjugates for use with multispecific antibodies |
| US7387772B1 (en) * | 1999-06-22 | 2008-06-17 | Immunimedics, Inc. | Chimeric, human and humanized anti-CSAP monoclonal antibodies |
| US7833528B2 (en) * | 1998-06-22 | 2010-11-16 | Immunomedics, Inc. | Use of multispecific, non-covalent complexes for targeted delivery of therapeutics |
| US6962702B2 (en) * | 1998-06-22 | 2005-11-08 | Immunomedics Inc. | Production and use of novel peptide-based agents for use with bi-specific antibodies |
| US7138103B2 (en) * | 1998-06-22 | 2006-11-21 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
| US6361774B1 (en) | 1999-09-17 | 2002-03-26 | Immunomedics, Inc. | Methods and compositions for increasing the target-specific toxicity of a chemotherapy drug |
| DE60040556D1 (de) | 1999-12-06 | 2008-11-27 | Univ Illinois | Hochaffine t-zellrezeptorproteine und verfahren |
| US7897140B2 (en) | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
| AU2001272017A1 (en) * | 2000-06-20 | 2002-01-02 | Immunomedics Inc. | Targeted combination immunotherapy of cancer and infectious diseases |
| US20020165149A1 (en) * | 2000-12-08 | 2002-11-07 | Kranz David M. | Mutated class II major histocompatibility proteins |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| EP1372741B1 (de) * | 2001-03-30 | 2006-08-09 | University of Massachusetts | Morpholinobildgebung und therapie |
| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US8877901B2 (en) | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| WO2004002476A2 (en) | 2002-06-27 | 2004-01-08 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
| EP1606291A2 (de) | 2002-07-02 | 2005-12-21 | Health Research, Inc. | Effiziente synthese von pyropheophorbid-a und seiner derivate |
| US20060024289A1 (en) * | 2002-10-02 | 2006-02-02 | Ruggles Sandra W | Cleavage of VEGF and VEGF receptor by wild-type and mutant proteases |
| US7939304B2 (en) * | 2002-10-02 | 2011-05-10 | Catalyst Biosciences, Inc. | Mutant MT-SP1 proteases with altered substrate specificity or activity |
| JP4874090B2 (ja) | 2003-01-31 | 2012-02-08 | イミューノメディクス、インコーポレイテッド | 治療薬および診断薬を投与するための方法および組成物 |
| US7057100B2 (en) * | 2003-06-26 | 2006-06-06 | The J.C. Robinson Seed Co. | Inbred corn line W23129 |
| US8038983B2 (en) * | 2003-07-29 | 2011-10-18 | Immunomedics, Inc. | Fluorinated carbohydrate conjugates |
| PT1733056E (pt) | 2004-03-31 | 2013-08-29 | Gen Hospital Corp | Método para determinar a responsividade do cancro a tratamentos visando o receptor do factor de crescimento epidérmico |
| DK1735439T3 (da) * | 2004-04-12 | 2012-02-06 | Catalyst Biosciences Inc | Spaltning af VEGF og VEGF receptor ved hjælp af vild-type og mutant MT-SP1 |
| US20050260131A1 (en) * | 2004-05-20 | 2005-11-24 | General Electric Company | Pharmaceuticals for enhanced delivery to disease targets |
| DK2298815T3 (en) | 2005-07-25 | 2015-06-15 | Emergent Product Dev Seattle | B-CELL REDUCTION USING CD37 SPECIFIC AND CD20 SPECIFIC BINDING MOLECULES |
| EP2674440B1 (de) | 2005-12-16 | 2019-07-03 | IBC Pharmaceuticals, Inc. | Polyvalente bioaktive anordnungen auf immunglobulinbasis |
| MX363905B (es) | 2006-06-12 | 2019-04-08 | Aptevo Res & Development Llc | Proteinas de union multivalentes monocatenarias con funcion efectora. |
| ES2579437T3 (es) | 2006-07-05 | 2016-08-11 | Catalyst Biosciences, Inc. | Procedimientos de cribado de proteasas y proteasas identificadas por los mismos |
| ATE513856T1 (de) | 2008-04-11 | 2011-07-15 | Emergent Product Dev Seattle | Cd37-immuntherapeutikum und kombination mit bifunktionellem chemotherapeutikum davon |
| LT3912643T (lt) | 2009-02-13 | 2023-02-10 | Immunomedics Inc. | Imunokonjugatai su ląstelės viduje skaldoma jungtimi |
| US8012770B2 (en) | 2009-07-31 | 2011-09-06 | Invisible Sentinel, Inc. | Device for detection of antigens and uses thereof |
| WO2011044186A1 (en) | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Human single-chain t cell receptors |
| US9557330B2 (en) | 2009-10-09 | 2017-01-31 | Invisible Sentinel, Inc. | Device for detection of analytes and uses thereof |
| ES2745140T3 (es) | 2011-01-27 | 2020-02-27 | Invisible Sentinel Inc | Dispositivos de detección de analitos, dispositivos multiplex y de sobremesa para la detección de analitos y usos de los mismos |
| US9745631B2 (en) | 2011-12-20 | 2017-08-29 | Dana-Farber Cancer Institute, Inc. | Methods for diagnosing and treating oncogenic kras-associated cancer |
| ES2742864T3 (es) | 2012-03-09 | 2020-02-17 | Invisible Sentinel Inc | Métodos y composiciones para detectar múltiples analitos con una única señal |
| CA2874521A1 (en) | 2012-05-24 | 2013-11-28 | Dana-Farber Cancer Institute, Inc. | Targeting the glutamine to pyruvate pathway for treatment of oncogenic kras-associated cancer |
| US20150285802A1 (en) | 2012-07-18 | 2015-10-08 | Dana-Farber Cancer Institute, Inc. | Methods for treating, preventing and predicting risk of developing breast cancer |
| HK1211039A1 (en) | 2012-07-27 | 2016-05-13 | The Board Of Trustees Of The University Of Illinois | Engineering t-cell receptors |
| EP3586874A1 (de) | 2012-08-14 | 2020-01-01 | IBC Pharmaceuticals, Inc. | Umleitung t-zell-bispezifischer antikörper zur behandlung von krankheiten |
| JP6366111B2 (ja) | 2012-12-13 | 2018-08-01 | イミューノメディクス、インコーポレイテッドImmunomedics, Inc. | 有効性の改善および毒性の減少のための、抗体およびsn−38からなるイムノコンジュゲートの投薬 |
| WO2017004144A1 (en) | 2015-07-01 | 2017-01-05 | Immunomedics, Inc. | Antibody-sn-38 immunoconjugates with a cl2a linker |
| US9931412B2 (en) | 2013-02-08 | 2018-04-03 | The Regents Of The University Of Michigan | Targeted theranostics |
| EP3036248B1 (de) | 2013-08-19 | 2020-05-27 | Abbott Molecular Inc. | Nukleotidanaloga |
| US10130590B2 (en) | 2013-10-01 | 2018-11-20 | Dana-Farber Cancer Institute, Inc. | Methods of treating cancer with atovaquone-related compounds |
| CN105899530B (zh) | 2013-11-22 | 2020-05-08 | 伊利诺伊州大学理事会 | 工程化的高亲和力人类t细胞受体 |
| WO2015149006A2 (en) | 2014-03-27 | 2015-10-01 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating ncoa4-mediated autophagic targeting of ferritin |
| US10555926B2 (en) | 2015-02-17 | 2020-02-11 | Erasmus University Medical Center Rotterdam | Use of cabazitaxel in the treatment of prostate cancer |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| WO2017151836A1 (en) | 2016-03-04 | 2017-09-08 | East Carolina University | J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders |
| WO2018035281A1 (en) | 2016-08-17 | 2018-02-22 | North Carolina State University | Northern-southern route to synthesis of bacteriochlorins |
| WO2018102252A1 (en) | 2016-11-30 | 2018-06-07 | North Carolina State University | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds |
| EP3675866B1 (de) | 2017-09-01 | 2023-08-02 | East Carolina University | Ex vivo verfahren zur aktivierung von immunzellen |
| JP2022532925A (ja) | 2019-05-20 | 2022-07-20 | ニルバナ サイエンシーズ インク. | 発光波長の範囲が狭い発光染料、それを含む組成物及びそれを製造及び使用する方法 |
| CA3138403A1 (en) | 2019-05-20 | 2020-11-26 | Christopher J. MACNEVIN | Narrow emission dyes, compositions comprising same, and methods for making and using same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2719102A (en) * | 1949-10-28 | 1955-09-27 | Corn States Serum Company | Clostridium perfringens toxoid and process of making the same |
| US4086217A (en) * | 1976-03-03 | 1978-04-25 | Hoffmann-La Roche Inc. | Carcinoembryonic antigens |
| US4228236A (en) * | 1978-05-15 | 1980-10-14 | Northwestern University | Process of producing carcinoembryonic antigen |
-
1981
- 1981-06-01 US US06/269,115 patent/US4468457A/en not_active Expired - Fee Related
-
1982
- 1982-05-27 DE DE8282104604T patent/DE3271119D1/de not_active Expired
- 1982-05-27 AT AT82104604T patent/ATE19792T1/de not_active IP Right Cessation
- 1982-05-27 EP EP82104604A patent/EP0066786B1/de not_active Expired
- 1982-05-31 CA CA000404077A patent/CA1183451A/en not_active Expired
- 1982-05-31 IL IL65915A patent/IL65915A/xx unknown
- 1982-06-01 JP JP57502209A patent/JPS58501355A/ja active Pending
- 1982-06-01 WO PCT/US1982/000746 patent/WO1982004263A1/en not_active Ceased
- 1982-06-01 AU AU87318/82A patent/AU550306B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0066786A3 (en) | 1983-07-20 |
| JPS58501355A (ja) | 1983-08-18 |
| EP0066786A2 (de) | 1982-12-15 |
| IL65915A0 (en) | 1982-08-31 |
| US4468457A (en) | 1984-08-28 |
| CA1183451A (en) | 1985-03-05 |
| EP0066786B1 (de) | 1986-05-14 |
| WO1982004263A1 (en) | 1982-12-09 |
| AU550306B2 (en) | 1986-03-13 |
| AU8731882A (en) | 1982-12-07 |
| DE3271119D1 (en) | 1986-06-19 |
| IL65915A (en) | 1985-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |