ATE176156T1 - Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff - Google Patents

Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff

Info

Publication number
ATE176156T1
ATE176156T1 AT90904479T AT90904479T ATE176156T1 AT E176156 T1 ATE176156 T1 AT E176156T1 AT 90904479 T AT90904479 T AT 90904479T AT 90904479 T AT90904479 T AT 90904479T AT E176156 T1 ATE176156 T1 AT E176156T1
Authority
AT
Austria
Prior art keywords
antigen
disclosed
methods
acrosomal
contraceptive vaccine
Prior art date
Application number
AT90904479T
Other languages
English (en)
Inventor
John C Herr
Richard M Wright
Original Assignee
Univ Virginia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia filed Critical Univ Virginia
Application granted granted Critical
Publication of ATE176156T1 publication Critical patent/ATE176156T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/811—Drug, bio-affecting and body treating compositions involving sex selection or contraception
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/852—Sperm

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90904479T 1989-03-03 1990-03-02 Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff ATE176156T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31855189A 1989-03-03 1989-03-03
US07/481,491 US5436157A (en) 1989-03-03 1990-02-16 Human intra-acrosomal sperm antigen

Publications (1)

Publication Number Publication Date
ATE176156T1 true ATE176156T1 (de) 1999-02-15

Family

ID=26981546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90904479T ATE176156T1 (de) 1989-03-03 1990-03-02 Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff

Country Status (11)

Country Link
US (1) US5436157A (de)
EP (1) EP0461177B1 (de)
JP (1) JPH04505008A (de)
AT (1) ATE176156T1 (de)
AU (1) AU649609B2 (de)
CA (1) CA2050910C (de)
DE (1) DE69032922T2 (de)
DK (1) DK0461177T3 (de)
ES (1) ES2130121T3 (de)
NO (1) NO312594B1 (de)
WO (1) WO1990009802A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346990A (en) * 1987-04-08 1994-09-13 Cytogam, Inc. Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
US5605803A (en) * 1989-03-03 1997-02-25 University Of Virginia Alumni Patents Foundation Human sperm diagnostic
JP2651249B2 (ja) * 1989-09-27 1997-09-10 扶桑薬品工業 株式会社 精子の受精能試験具および試験法
FR2660069B1 (fr) * 1990-03-20 1994-03-04 Recherche Developpement Activ Co Procede pour la mise en evidence de la capacite d'un spermatozouide a subir la reaction acrosomale.
US5721348A (en) * 1990-12-14 1998-02-24 University Of Connecticut DNA encoding PH-20 proteins
WO1995018630A1 (en) * 1994-01-03 1995-07-13 Mauno Sakari Reiala A method to produce a substance to inhibit cell penetration, and a contraceptive to prevent conception, and a thrombus, prostate and aids vaccine and medicine
WO1997027218A1 (en) * 1996-01-29 1997-07-31 U.S. Environmental Protection Agency Method for evaluating and affecting male fertility
US7211255B2 (en) 1996-01-29 2007-05-01 United States Of America The U.S. Environmental Protection Agency Contraceptives based on SP22 and SP22 antibodies
US5830472A (en) * 1996-06-28 1998-11-03 The University Of Virginia Patent Foundation Purified sperm surface antigen, monoclonal antibody therefor and applications therefor
US6258364B1 (en) 1996-06-28 2001-07-10 University Of Virginia Patent Foundation Purified sperm surface antigen, monoclonal antibody therefor and application therefor
GB9812534D0 (en) * 1998-06-10 1998-08-05 Medical Res Council Sperm protein
AU753753B2 (en) * 1998-11-13 2002-10-24 Euro-Celtique S.A. Contraceptive antibody vaccines
GB9913556D0 (en) * 1999-06-11 1999-08-11 Zeneca Ltd Assays
US6844164B1 (en) * 1999-10-26 2005-01-18 Fuso Pharmaceutical Industries, Ltd. Antibody against rat postacrosome reaction sperm and utilization thereof
AU2001240103A1 (en) * 2000-03-07 2001-09-17 Whitehead Institute For Biomedical Research Reproduction-specific genes
WO2003002908A1 (en) * 2000-06-26 2003-01-09 Reveo, Inc. Backlight for a liquid crystal display having high light-recycling efficiency
GB0114922D0 (en) * 2001-06-19 2001-08-08 Sec Dep Of The Home Department Improvements in and relating to identification and analysis
US20080318250A1 (en) * 2004-02-06 2008-12-25 Linda Gilmer Compositions and Methods for Identifying Sperm for Forensic Applications
FR2877575B1 (fr) * 2004-11-05 2012-11-16 Union Nationale Des Cooperatives Agricoles D Elevage Et D Insemination Animale Milieu protecteur pour semence
WO2007095530A2 (en) 2006-02-13 2007-08-23 U.S. Environmental Protection Agency Diagnostic kits to detect sp22 and sp22 antibodies
US20110294782A1 (en) 2006-11-10 2011-12-01 Massachusetts Institute Of Technology Small molecule pak inhibitors
EP2188027A4 (de) * 2007-09-11 2011-06-08 Arryx Inc Bindeverfahren und vorrichtung zum sortieren von objekten
JP2010538644A (ja) * 2007-09-13 2010-12-16 アリックス インク 法医学的ｄｎａ分析および医学的診断において対象物を選別するための方法および装置
WO2014093417A1 (en) 2012-12-12 2014-06-19 University Of Virginia Patent Foundation Compositions and methods for regulating erythropoiesis
US10030241B2 (en) 2015-03-30 2018-07-24 General Electric Company Methods and kits for capturing sperm nucleic acids
US9957548B2 (en) 2015-03-30 2018-05-01 General Electric Company Methods of capturing sperm nucleic acids
US10384207B2 (en) 2015-07-21 2019-08-20 Neuro Probe Incorporated Assay apparatus and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1239346A (en) * 1985-06-04 1988-07-19 Gursaran P. Talwar Birth control vaccine
US4741998A (en) * 1985-06-05 1988-05-03 The University Of Virginia Alumni Patents Foundation Monoclonal antibody to MHS-5: a new probe for sexual assault analyses
US5047508A (en) * 1985-06-05 1991-09-10 The University Of Virginia Alumni Patents Foundation Monoclonal antibody to MHS-5; a new probe for sexual assault analysis
US4782136A (en) * 1986-12-01 1988-11-01 Northwestern University Synthetic peptide compounds producing anitbodies binding to human LDH-C.sub.
US5232834A (en) * 1989-03-15 1993-08-03 Fuso Pharmaceutical Industries, Ltd. Anti-human sperm antibody, and its production and use

Also Published As

Publication number Publication date
AU5186290A (en) 1990-09-26
DK0461177T3 (da) 1999-09-13
ES2130121T3 (es) 1999-07-01
US5436157A (en) 1995-07-25
NO312594B1 (no) 2002-06-03
JPH04505008A (ja) 1992-09-03
NO913428D0 (no) 1991-09-02
EP0461177B1 (de) 1999-01-27
EP0461177A1 (de) 1991-12-18
DE69032922T2 (de) 1999-09-30
WO1990009802A1 (en) 1990-09-07
AU649609B2 (en) 1994-06-02
CA2050910C (en) 2002-12-03
EP0461177A4 (en) 1993-01-07
DE69032922D1 (de) 1999-03-11
NO913428L (no) 1991-10-18
CA2050910A1 (en) 1990-09-04

Similar Documents

Publication Publication Date Title
DE69032922D1 (de) Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff
ATE301471T1 (de) Verwendung von antikörpen gegen cd45ro leukozytenantigen zur immunmodulation
DE69521794D1 (de) Zellen mit mehreren geänderten epitopen auf einem oberflächeantigen zur verwendung in transplantation
DK0612250T3 (da) Fremgangsmåder og præparater med relation til nyttige Moraxella catarrhalis-antigener
DE69032806T2 (de) Verfahren zur isolierung und reinigung von rezeptoren für transferrin und lactoferrin von bakterien und herstellung von impfstoffen, die sie enthalten
KR910016346A (ko) 광견병 바이러스에 대한 사람 모노클로날 항체, 이의 제조방법 및 용도
ATE166230T1 (de) Verwendung von anti-icam antikörpern zur herstellung eines präparats für die behandlung von endotoxinschock
Sandberg et al. Initiation of bone resorption by the classical and alternative C pathways and its mediation by prostaglandins
EP0350690A3 (de) Neutralisation der in vitro- und in vivo-toxischen Eigenschaften von TNF-alfa durch monoklonale Antikörper und die davon abgeleiteten Fragmente
DK0476226T3 (da) Monoklonalt antistof mod humant IgE
DE3584872D1 (de) Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag.
Franko et al. Monoclonal antibody analysis of keratin expression in the central nervous system.
DE69015230T2 (de) Antikörper gegen menschliches Sperma, ihre Herstellung und Anwendung.
KR890016165A (ko) 수도모나스 아에루기노사(Pseudomonas aeruginosa)에 대한 모노클로날 항체, 이의 제조방법 및 용도
Liu et al. Cytotoxic effect of nephrotoxic serum on rat tissue culture.
Bose Human embryo associated immunosuppressor factor (s) from pre-and post-implantation stages share some similarities
JPS6445398A (en) Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
FR2571146B1 (fr) Antigenes carcino-foetaux du pancreas humain et un procede de purification, antiserum contre ces antigenes et son procede de preparation et compositions diagnostiques les contenant
Gratecos et al. A new approach to monoclonal antibody production In vitro immunization with antigens on nitrocellulose using Drosphila myosin heavy chain as an example
Herr et al. Human intra-acrosomal sperm antigen
KR880001806A (ko) γ-인터페론의 제조방법과 그 용도
Shiraishi et al. Immunology: Diagnostic relevance of abortion-associated human embryonic antigen expressed on the cell surface of tumour promoter-treated Bloom syndrome cells
Imami et al. K21-antigen: a molecule shared by the microenvironments of the human thymus and germinal centers
Ovary The history of immediate hypersensitivity
KR880006359A (ko) 사람의 tiits를 제조하기 위한 중간물질로서의 균일한 양 tiits 및 이의 용도

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee