JPS565239B2 - - Google Patents

Info

Publication number
JPS565239B2
JPS565239B2 JP9026674A JP9026674A JPS565239B2 JP S565239 B2 JPS565239 B2 JP S565239B2 JP 9026674 A JP9026674 A JP 9026674A JP 9026674 A JP9026674 A JP 9026674A JP S565239 B2 JPS565239 B2 JP S565239B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP9026674A
Other versions
JPS5126876A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP49090266A priority Critical patent/JPS5126876A/ja
Priority to ZA00754895A priority patent/ZA754895B/xx
Priority to US05/600,206 priority patent/US4086415A/en
Priority to IL47842A priority patent/IL47842A/xx
Priority to GB31941/75A priority patent/GB1507099A/en
Priority to SE7508840A priority patent/SE430340B/xx
Priority to FR7525015A priority patent/FR2281102A1/fr
Priority to DE19752560038 priority patent/DE2560038C2/de
Priority to CA75232963A priority patent/CA1049004A/en
Priority to HU75SU897A priority patent/HU175174B/hu
Priority to DE2535048A priority patent/DE2535048C3/de
Priority to BE159028A priority patent/BE832227A/xx
Priority to YU2034/75A priority patent/YU39743B/xx
Priority to NL7509445A priority patent/NL7509445A/xx
Priority to CH1033175A priority patent/CH619967A5/de
Priority to AT618475A priority patent/AT351555B/de
Priority to AU83804/75A priority patent/AU491724B2/en
Priority to ES440147A priority patent/ES440147A1/es
Publication of JPS5126876A publication Critical patent/JPS5126876A/ja
Priority to US05/870,884 priority patent/US4180655A/en
Publication of JPS565239B2 publication Critical patent/JPS565239B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP49090266A 1974-08-08 1974-08-08 Shinkina nitorosonyosojudotaino seizohoho Granted JPS5126876A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
JP49090266A JPS5126876A (en) 1974-08-08 1974-08-08 Shinkina nitorosonyosojudotaino seizohoho
ZA00754895A ZA754895B (en) 1974-08-08 1975-07-29 New nitrosourea derivatives
US05/600,206 US4086415A (en) 1974-08-08 1975-07-30 Nitrosourea derivatives of glycosides
IL47842A IL47842A (en) 1974-08-08 1975-07-30 Nitroso urea glycosides and related compounds,their preparation and pharmaceutical compositions containing them
GB31941/75A GB1507099A (en) 1974-08-08 1975-07-30 Nitrosourea derivatives
SE7508840A SE430340B (sv) 1974-08-08 1975-08-05 Forfarande for framstellning av nya nitrosokarbamidderivat
HU75SU897A HU175174B (hu) 1974-08-08 1975-08-06 Sposob poluchenija proizvodnykh nitrozo-mocheviny
DE19752560038 DE2560038C2 (de) 1974-08-08 1975-08-06 H2-Chloräthyl)-1 nitroso-3-(hydroxycyclohexyl)harnstoffe, dieselben enthaltende Arzneimittel und Verfahren zur Herstellung der ersteren
CA75232963A CA1049004A (en) 1974-08-08 1975-08-06 Nitrosourea derivatives
FR7525015A FR2281102A1 (fr) 1974-08-08 1975-08-06 Nouveaux derives de nitrosouree et procede pour leur preparation
DE2535048A DE2535048C3 (de) 1974-08-08 1975-08-06 1 -(2-Chloräthyl)-1 -nitroso-3-glycosylharnstoffe, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung der ersteren
NL7509445A NL7509445A (nl) 1974-08-08 1975-08-07 Nieuwe nitrosoureumderivaten.
YU2034/75A YU39743B (en) 1974-08-08 1975-08-07 Process for preparing nitrosourea derivatives
BE159028A BE832227A (fr) 1974-08-08 1975-08-07 Nouvelles nitrosourees
CH1033175A CH619967A5 (en) 1974-08-08 1975-08-07 Process for the preparation of nitrosourea derivatives
AT618475A AT351555B (de) 1974-08-08 1975-08-08 Verfahren zur herstellung von neuen nitro- soharnstoff-derivaten
AU83804/75A AU491724B2 (en) 1975-08-08 New nitrosourea derivatives
ES440147A ES440147A1 (es) 1974-08-08 1975-08-08 Un proceso para la preparacion de derivados de la nitrosou- rea.
US05/870,884 US4180655A (en) 1974-08-08 1978-01-20 Nitrosourea derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49090266A JPS5126876A (en) 1974-08-08 1974-08-08 Shinkina nitorosonyosojudotaino seizohoho

Publications (2)

Publication Number Publication Date
JPS5126876A JPS5126876A (en) 1976-03-05
JPS565239B2 true JPS565239B2 (ja) 1981-02-04

Family

ID=13993689

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49090266A Granted JPS5126876A (en) 1974-08-08 1974-08-08 Shinkina nitorosonyosojudotaino seizohoho

Country Status (5)

Country Link
US (1) US4086415A (ja)
JP (1) JPS5126876A (ja)
BE (1) BE832227A (ja)
CA (1) CA1049004A (ja)
ZA (1) ZA754895B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180655A (en) * 1974-08-08 1979-12-25 Tetsuo Suami Nitrosourea derivatives
JPS5395917A (en) 1977-02-03 1978-08-22 Tokyo Tanabe Co Process for preparing nitrosourea derivative of glucopyranose
FI65781C (fi) * 1977-06-15 1984-07-10 Ciba Geigy Ag Analogifoerfarande foer framstaellning av terapeutiskt verkande n1-glukofuranosid-6-yl-n3-nitroso-urinaemnen
US4148921A (en) * 1977-07-13 1979-04-10 Suami T Antitumor agents
US4182757A (en) * 1977-07-29 1980-01-08 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
JPS5924997B2 (ja) * 1977-10-03 1984-06-13 日本新薬株式会社 アシル化２−〔３−（２−クロロエチル）−３−ニトロソウレイド〕−２−デオキシグルコピラノ−ス誘導体
JPS5463069A (en) * 1977-10-27 1979-05-21 Suami T Novel nitrosourea compound and its manufacture
DE2753769A1 (de) * 1977-12-02 1979-06-13 Bayer Ag 1-n-4,6-di-o-(aminoglykosyl)-1,3- diamino-cyclitol-derivate, verfahren zu ihrer herstellung sowie ihre verwendung
HU176101B (en) * 1977-12-29 1980-12-28 Gyogyszerkutato Intezet Process for producing bis-bracket-nitrozo-ureido-bracket closed-polyol derivatives
JPS54151918A (en) * 1978-04-15 1979-11-29 Suami T Novel nitroso urea derivative and its manufacture
US4241052A (en) * 1978-06-10 1980-12-23 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
US4241053A (en) * 1978-08-25 1980-12-23 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
JPS57165398A (en) * 1981-04-02 1982-10-12 Tanabe Seiyaku Co Ltd Nitrosourea derivative and its preparation
JPS57200397A (en) * 1981-06-03 1982-12-08 Akira Kimura Novel aldohexopyranose-, aldopentopyranose-, or and medicament composition comprising it aldopentofuranose- nitrosourea compound, its preparation
DE3323095A1 (de) * 1983-06-27 1985-01-03 Institut organičeskoj chimii Akademii Nauk Kirgizskoj SSR, Frunze Verfahren zur herstellung von n-alkyl-n'-glykosyl-n-nitrosourethan
US4656259A (en) * 1983-06-29 1987-04-07 Institut Organicheskoy Khimii Akademii Nauk Kirgizskoi Method for preparing N-alkyl-N'-glycosyl-N-nitrosourea
GB0619395D0 (en) * 2006-10-02 2006-11-08 Almac Sciences Ltd Soluble diazoalkane precursors
CN109721510B (zh) * 2018-12-28 2021-03-23 浙江大学 神经酰胺类似物b及其制备方法、应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577406A (en) * 1968-05-23 1971-05-04 Upjohn Co Process for preparing the antibiotic streptozotocin
CH518270A (de) * 1969-03-07 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von Nitrosoharnstoffverbindungen
JPS4843333B1 (ja) * 1970-04-25 1973-12-18

Also Published As

Publication number Publication date
JPS5126876A (en) 1976-03-05
CA1049004A (en) 1979-02-20
BE832227A (fr) 1975-12-01
US4086415A (en) 1978-04-25
ZA754895B (en) 1976-09-29

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