JPS5646841A - Mb-530b carboxylic acid ester and its preparation - Google Patents
Mb-530b carboxylic acid ester and its preparationInfo
- Publication number
- JPS5646841A JPS5646841A JP12346179A JP12346179A JPS5646841A JP S5646841 A JPS5646841 A JP S5646841A JP 12346179 A JP12346179 A JP 12346179A JP 12346179 A JP12346179 A JP 12346179A JP S5646841 A JPS5646841 A JP S5646841A
- Authority
- JP
- Japan
- Prior art keywords
- carboxylic acid
- alkyl
- acid ester
- preparation
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003262 carboxylic acid ester group Chemical class [H]C([H])([*:2])OC(=O)C([H])([H])[*:1] 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 MB-530B carboxylic acid ester Chemical class 0.000 abstract 2
- 241000228347 Monascus <ascomycete fungus> Species 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- LXZBFUBRYYVRQJ-AXHZAXLDSA-M sodium;(3r,5r)-7-[(1s,2s,6r,8s,8ar)-2,6-dimethyl-8-[(2s)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate Chemical compound [Na+].C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@@H](C)C=C21 LXZBFUBRYYVRQJ-AXHZAXLDSA-M 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 1
- 239000003524 antilipemic agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12346179A JPS5646841A (en) | 1979-09-26 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
| ES493726A ES493726A0 (es) | 1979-07-27 | 1980-07-24 | Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos. |
| NZ194445A NZ194445A (en) | 1979-07-27 | 1980-07-25 | Monacolin k salts and esters |
| CH5736/80A CH647749A5 (de) | 1979-07-27 | 1980-07-25 | Salze und ester von monacolin-k, verfahren zu ihrer herstellung und pharmazeutische praeparate. |
| FR8016452A FR2462417A1 (fr) | 1979-07-27 | 1980-07-25 | Nouveaux derives de la monacoline k, leur procede de preparation et leur application en therapeutique |
| FI802357A FI71300C (fi) | 1979-07-27 | 1980-07-25 | Foerfarande foer framstaellning av salter och estrar av syran som svarar mot monakolin-k vilka har antihyperkolesteremisk effekt |
| NO802244A NO156210C (no) | 1979-07-27 | 1980-07-25 | Fremgangsmaate til fremstilling av monacolin k derivater. |
| SE8005386A SE445828B (sv) | 1979-07-27 | 1980-07-25 | Salter och estrar av monakolin k till anvendning sasom antihyperkolesterolemiska medel |
| DE19803028284 DE3028284A1 (de) | 1979-07-27 | 1980-07-25 | Monacolin k-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel |
| DE19803051206 DE3051206C2 (de) | 1979-07-27 | 1980-07-25 | Verfahren zur fermentativen Herstellung von Monacolin K |
| DK322380A DK322380A (da) | 1979-07-27 | 1980-07-25 | Fr&mgangsmaade til fremstilling af monacolin k salte eller estere |
| PL22590180A PL225901A1 (enrdf_load_stackoverflow) | 1979-07-27 | 1980-07-26 | |
| NL8004303A NL8004303A (nl) | 1979-07-27 | 1980-07-27 | Monacoline k verbindingen. |
| DD80222916A DD153827A5 (de) | 1979-07-27 | 1980-07-28 | Verfahren zur herstellung von antihypercholesterinaemischen mitteln |
| AU60839/80A AU6083980A (en) | 1979-07-27 | 1980-07-28 | Monacolin k derivatives |
| IT68211/80A IT1147763B (it) | 1979-07-27 | 1980-07-28 | Composti utilizzabili come agenti inibitori della biosintesi del colesterolo e procedimento per la loro preparazione |
| AT0392380A AT375334B (de) | 1979-07-27 | 1980-07-28 | Verfahren zum herstellen von neuen salzen oder estern |
| GB8024665A GB2055100A (en) | 1979-07-27 | 1980-07-28 | Monacolin K derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12346179A JPS5646841A (en) | 1979-09-26 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5646841A true JPS5646841A (en) | 1981-04-28 |
| JPS6320215B2 JPS6320215B2 (enrdf_load_stackoverflow) | 1988-04-26 |
Family
ID=14861197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12346179A Granted JPS5646841A (en) | 1979-07-27 | 1979-09-26 | Mb-530b carboxylic acid ester and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5646841A (enrdf_load_stackoverflow) |
-
1979
- 1979-09-26 JP JP12346179A patent/JPS5646841A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6320215B2 (enrdf_load_stackoverflow) | 1988-04-26 |
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