JPS5634698A - N6-acyl-3'-o(o-nitrobenzyl)adenosine-5'-monophosphate and its preparation - Google Patents
N6-acyl-3'-o(o-nitrobenzyl)adenosine-5'-monophosphate and its preparationInfo
- Publication number
- JPS5634698A JPS5634698A JP11152279A JP11152279A JPS5634698A JP S5634698 A JPS5634698 A JP S5634698A JP 11152279 A JP11152279 A JP 11152279A JP 11152279 A JP11152279 A JP 11152279A JP S5634698 A JPS5634698 A JP S5634698A
- Authority
- JP
- Japan
- Prior art keywords
- adenosine
- acyl
- monophosphate
- substituted
- nitrobenzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
Abstract
NEW MATERIAL:An N6-acyl-3'-O(o-nitro-4- and/or 5-substituted or unsubstituted benzyl)adenosine-5'-monophosphate of formula I [X is acyl or (substituted) trityl; NB is o-nitrobenzyl], or its salt.
USE: Intermediate for the synthesis of 5'-triphosphoryladenylyl-(2'-5')-adenylyl-(2'- 5')-adenosine of formula II which is a protein-synthesis inhibiting material.
PROCESS: The compound of formula I is prepared by (1) converting the 5'-OH group of N6-acyl or (substituted) trityl-3'-O(o-nitro-4- and/or 5-substituted or unsubstituted benzyl]adenosine to monophosphate, and if necessary, (2) converting the free acid thus obtained to a salt.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11152279A JPS5634698A (en) | 1979-08-31 | 1979-08-31 | N6-acyl-3'-o(o-nitrobenzyl)adenosine-5'-monophosphate and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11152279A JPS5634698A (en) | 1979-08-31 | 1979-08-31 | N6-acyl-3'-o(o-nitrobenzyl)adenosine-5'-monophosphate and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5634698A true JPS5634698A (en) | 1981-04-06 |
Family
ID=14563454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11152279A Pending JPS5634698A (en) | 1979-08-31 | 1979-08-31 | N6-acyl-3'-o(o-nitrobenzyl)adenosine-5'-monophosphate and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5634698A (en) |
-
1979
- 1979-08-31 JP JP11152279A patent/JPS5634698A/en active Pending
Non-Patent Citations (2)
Title |
---|
CHEM. PHARM. BULL.=1977 * |
NUCLEIC ACID RESEARCH=1976 * |
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