JPS5634699A - (2'-5')polyadenylic acid compound and its preparation - Google Patents

(2'-5')polyadenylic acid compound and its preparation

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Publication number
JPS5634699A
JPS5634699A JP11152379A JP11152379A JPS5634699A JP S5634699 A JPS5634699 A JP S5634699A JP 11152379 A JP11152379 A JP 11152379A JP 11152379 A JP11152379 A JP 11152379A JP S5634699 A JPS5634699 A JP S5634699A
Authority
JP
Japan
Prior art keywords
group
formula
substituted
acid compound
polyadenylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11152379A
Other languages
Japanese (ja)
Other versions
JPS6126915B2 (en
Inventor
Morio Ikehara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WAKINAGA YAKUHIN KK
Wakunaga Pharmaceutical Co Ltd
Original Assignee
WAKINAGA YAKUHIN KK
Wakunaga Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WAKINAGA YAKUHIN KK, Wakunaga Pharmaceutical Co Ltd filed Critical WAKINAGA YAKUHIN KK
Priority to JP11152379A priority Critical patent/JPS5634699A/en
Publication of JPS5634699A publication Critical patent/JPS5634699A/en
Publication of JPS6126915B2 publication Critical patent/JPS6126915B2/ja
Granted legal-status Critical Current

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Abstract

NEW MATERIAL:A (2'-5')polyadenylic acid compound of formula I [the group of formula II is a residue of the group of formula III; NB is o-nitro-4- and/or 5-substituted or unsubstituted benzyl; n is 0W2], or its salt.
USE: An intermediate for the synthesis of 5'-triphosphoryladenylyl-(2'-5')-adenylyl- (2'-5')adenosine which is a protein-synthesis inhibiting material.
PROCESS: The objective compound of formula I is prepared by (1) condensing N6- acyl or substituted or unsubstituted trityl-3'-O[o-nitro-4- and/or 5-substituted or unsubstituted benzyl]adenosine-monophosphate by reacting with a condensing agent (2) hydrolyzing the condensation product to eliminate the N6-acyl group or the N6- trityl group, and if nexessary, (3) converting the free acid thus obtained to a salt.
COPYRIGHT: (C)1981,JPO&Japio
JP11152379A 1979-08-31 1979-08-31 (2'-5')polyadenylic acid compound and its preparation Granted JPS5634699A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11152379A JPS5634699A (en) 1979-08-31 1979-08-31 (2'-5')polyadenylic acid compound and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11152379A JPS5634699A (en) 1979-08-31 1979-08-31 (2'-5')polyadenylic acid compound and its preparation

Publications (2)

Publication Number Publication Date
JPS5634699A true JPS5634699A (en) 1981-04-06
JPS6126915B2 JPS6126915B2 (en) 1986-06-23

Family

ID=14563481

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11152379A Granted JPS5634699A (en) 1979-08-31 1979-08-31 (2'-5')polyadenylic acid compound and its preparation

Country Status (1)

Country Link
JP (1) JPS5634699A (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEM. PHARM. BULL.=1977 *

Also Published As

Publication number Publication date
JPS6126915B2 (en) 1986-06-23

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