JPS5629581A - 4-phenylpiperazinyl alkoxy anilide derivative - Google Patents

4-phenylpiperazinyl alkoxy anilide derivative

Info

Publication number
JPS5629581A
JPS5629581A JP10639779A JP10639779A JPS5629581A JP S5629581 A JPS5629581 A JP S5629581A JP 10639779 A JP10639779 A JP 10639779A JP 10639779 A JP10639779 A JP 10639779A JP S5629581 A JPS5629581 A JP S5629581A
Authority
JP
Japan
Prior art keywords
compound
formula
phenylpiperazinyl
alkoxy
anilide derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10639779A
Other languages
Japanese (ja)
Other versions
JPS6334846B2 (en
Inventor
Kazuhisa Sakano
Takafumi Fujioka
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP10639779A priority Critical patent/JPS5629581A/en
Publication of JPS5629581A publication Critical patent/JPS5629581A/en
Publication of JPS6334846B2 publication Critical patent/JPS6334846B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A (4-phenylpiperazinyl) alkoxy anilide derivative of formula I (R1 is formyl, lower alkanoyl or benzoyl; R2 is halogen, lower alkyl or lower alkoxy; n is an integer 2W6; m is 0 or an integer 1W3).
EXAMPLE: 3-[3-(4-phenylpiperazinyl)propoxy]-formanilide.
USE: Useful as a medicine having analgesic, anti-inflammatory and hypotensive actions and as a preanesthetic medication, a sleep inducer, an analgesic, an antischizophrenic and an antihistaminic agents.
PROCESS: A compound of formula II is reacted with a compound of the formula X1(CH2)nX2 (X1 and X2 are halogens), preferably in the presence of a basic compound as a dehydrohalogenating agent, in a solvent, e.g. methanol, at room temperature W200°C, preferably 50W150°C, to give a compound of formula III, which is reacted with a compound of formula IV to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP10639779A 1979-08-20 1979-08-20 4-phenylpiperazinyl alkoxy anilide derivative Granted JPS5629581A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10639779A JPS5629581A (en) 1979-08-20 1979-08-20 4-phenylpiperazinyl alkoxy anilide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10639779A JPS5629581A (en) 1979-08-20 1979-08-20 4-phenylpiperazinyl alkoxy anilide derivative

Publications (2)

Publication Number Publication Date
JPS5629581A true JPS5629581A (en) 1981-03-24
JPS6334846B2 JPS6334846B2 (en) 1988-07-12

Family

ID=14432549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10639779A Granted JPS5629581A (en) 1979-08-20 1979-08-20 4-phenylpiperazinyl alkoxy anilide derivative

Country Status (1)

Country Link
JP (1) JPS5629581A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543792A (en) * 2005-06-17 2008-12-04 アンドルシェルシュ・インコーポレイテッド Helix 12-directed non-steroidal antiandrogen
JP2015516432A (en) * 2012-05-09 2015-06-11 スノビオン プハルマセウトイカルス インコーポレイテッド Heteroaryl compounds and methods of use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49110679A (en) * 1973-03-10 1974-10-22

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49110679A (en) * 1973-03-10 1974-10-22

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543792A (en) * 2005-06-17 2008-12-04 アンドルシェルシュ・インコーポレイテッド Helix 12-directed non-steroidal antiandrogen
JP2015516432A (en) * 2012-05-09 2015-06-11 スノビオン プハルマセウトイカルス インコーポレイテッド Heteroaryl compounds and methods of use thereof

Also Published As

Publication number Publication date
JPS6334846B2 (en) 1988-07-12

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