JPS5735588A - Carbostyrile derivative - Google Patents
Carbostyrile derivativeInfo
- Publication number
- JPS5735588A JPS5735588A JP11199380A JP11199380A JPS5735588A JP S5735588 A JPS5735588 A JP S5735588A JP 11199380 A JP11199380 A JP 11199380A JP 11199380 A JP11199380 A JP 11199380A JP S5735588 A JPS5735588 A JP S5735588A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- phenyl
- solvent
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:Compounds of formula I (R1 is H, lower alkenyl, lower alkynyl; R2 is H, lower alkyl, phenyl; R3 is lower alkyl, phenyl, R4 is H, hydroxyl, lower alkanoyl; X is halogen; Y is lower alkylene; n is 0W2; the dotted line is single or double bond) and their salts.
EXAMPLE: 5-[2-Hydroxy-3-(4-phenyl-1-piperidyl)propoxy]-3,4-dihydrocarbostyrile.
USE: Antihistamine.
PREPARATION: The reaction of a compound of formula 2 with a piperidine derivative of formula 3 is conducted using no solvent or an inert solvent such as dioxane at room temperature to 200°C to produce the compound of formula I. The compound of formula 2, the starting substance, is obtained by reaction of a compound of formula 8 with another compound of formula 9 (X1, X2 are halogen) in the presence of a dehalogenation agent in a solvent such as DMF at room temperature to 200°C.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11199380A JPS5735588A (en) | 1980-08-13 | 1980-08-13 | Carbostyrile derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11199380A JPS5735588A (en) | 1980-08-13 | 1980-08-13 | Carbostyrile derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5735588A true JPS5735588A (en) | 1982-02-26 |
JPS6320433B2 JPS6320433B2 (en) | 1988-04-27 |
Family
ID=14575251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11199380A Granted JPS5735588A (en) | 1980-08-13 | 1980-08-13 | Carbostyrile derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5735588A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60167326A (en) * | 1984-02-09 | 1985-08-30 | Matsushita Electronics Corp | Manufacture of semiconductor device |
-
1980
- 1980-08-13 JP JP11199380A patent/JPS5735588A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60167326A (en) * | 1984-02-09 | 1985-08-30 | Matsushita Electronics Corp | Manufacture of semiconductor device |
Also Published As
Publication number | Publication date |
---|---|
JPS6320433B2 (en) | 1988-04-27 |
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