JPS56122351A - Oxyindole derivative - Google Patents

Oxyindole derivative

Info

Publication number
JPS56122351A
JPS56122351A JP2565980A JP2565980A JPS56122351A JP S56122351 A JPS56122351 A JP S56122351A JP 2565980 A JP2565980 A JP 2565980A JP 2565980 A JP2565980 A JP 2565980A JP S56122351 A JPS56122351 A JP S56122351A
Authority
JP
Japan
Prior art keywords
formula
compound
lower alkyl
halogen
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2565980A
Other languages
Japanese (ja)
Other versions
JPS6341387B2 (en
Inventor
Kazuhisa Sakano
Takafumi Fujioka
Masaaki Osaki
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP2565980A priority Critical patent/JPS56122351A/en
Publication of JPS56122351A publication Critical patent/JPS56122351A/en
Publication of JPS6341387B2 publication Critical patent/JPS6341387B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula 1 [R1 is H, lower alkyl, phenyl(lower alkyl), etc.; R2 and R3 are lower alkyl; R4 is halogen, lower alkyl, lower alkoxy, etc.; n is 0W3; two R4 groups in -(R4)n may together form a lower alkylenedioxy group; A is lower alkylene], and its salt.
EXAMPLE: 5-[3-(4-Phenylpiperazinyl)propoxy]3,3-dimethyloxyindole.
USE: Central nervous system depressant and antihistaminic agent.
PROCESS: The compound of formula 1 can be prepared by (a) reacting oxyindole derivative of formula 2 with a compound of formula 3 (X and X' are halogen, lower alkanesulfonyloxy, etc.) at room temp.W200°C, and (b) reacting the resulting compound of formula 4 with a compound of formula 5 under the conditions similar to the first reaction.
COPYRIGHT: (C)1981,JPO&Japio
JP2565980A 1980-02-29 1980-02-29 Oxyindole derivative Granted JPS56122351A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2565980A JPS56122351A (en) 1980-02-29 1980-02-29 Oxyindole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2565980A JPS56122351A (en) 1980-02-29 1980-02-29 Oxyindole derivative

Publications (2)

Publication Number Publication Date
JPS56122351A true JPS56122351A (en) 1981-09-25
JPS6341387B2 JPS6341387B2 (en) 1988-08-17

Family

ID=12171928

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2565980A Granted JPS56122351A (en) 1980-02-29 1980-02-29 Oxyindole derivative

Country Status (1)

Country Link
JP (1) JPS56122351A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01193221A (en) * 1988-01-29 1989-08-03 Mitsubishi Kasei Corp Anxiolytic

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5041880A (en) * 1973-07-24 1975-04-16
JPS54160389A (en) * 1978-06-06 1979-12-19 Hoechst Ag Novel substituted phenylpiperazine derivative and its manufacture

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5041880A (en) * 1973-07-24 1975-04-16
JPS54160389A (en) * 1978-06-06 1979-12-19 Hoechst Ag Novel substituted phenylpiperazine derivative and its manufacture

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01193221A (en) * 1988-01-29 1989-08-03 Mitsubishi Kasei Corp Anxiolytic

Also Published As

Publication number Publication date
JPS6341387B2 (en) 1988-08-17

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