JPS54160389A - Novel substituted phenylpiperazine derivative and its manufacture - Google Patents

Novel substituted phenylpiperazine derivative and its manufacture

Info

Publication number
JPS54160389A
JPS54160389A JP7179679A JP7179679A JPS54160389A JP S54160389 A JPS54160389 A JP S54160389A JP 7179679 A JP7179679 A JP 7179679A JP 7179679 A JP7179679 A JP 7179679A JP S54160389 A JPS54160389 A JP S54160389A
Authority
JP
Japan
Prior art keywords
manufacture
novel substituted
phenylpiperazine derivative
substituted phenylpiperazine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7179679A
Other languages
Japanese (ja)
Other versions
JPS6353162B2 (en
Inventor
Ratsutoreru Rudorufu
Barutoman Buiruherumu
Geruharutsu Heruman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS54160389A publication Critical patent/JPS54160389A/en
Publication of JPS6353162B2 publication Critical patent/JPS6353162B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
JP7179679A 1978-06-06 1979-06-05 Novel substituted phenylpiperazine derivative and its manufacture Granted JPS54160389A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782824677 DE2824677A1 (en) 1978-06-06 1978-06-06 3-Phenyl:piperazino-propoxy-indoline and quinoline derivs. - useful as psychotropic and cardiovascular agents

Publications (2)

Publication Number Publication Date
JPS54160389A true JPS54160389A (en) 1979-12-19
JPS6353162B2 JPS6353162B2 (en) 1988-10-21

Family

ID=6041107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7179679A Granted JPS54160389A (en) 1978-06-06 1979-06-05 Novel substituted phenylpiperazine derivative and its manufacture

Country Status (3)

Country Link
JP (1) JPS54160389A (en)
DE (1) DE2824677A1 (en)
ZA (1) ZA792783B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56122351A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Oxyindole derivative
JPS56140970A (en) * 1980-04-04 1981-11-04 Ronza Chem:Kk Preparation of indole derivative
JPS62135423A (en) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd Improver for hypoxia
JPS63290821A (en) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd Antiarrhythmic
JPH04352723A (en) * 1991-05-31 1992-12-07 Otsuka Pharmaceut Co Ltd Akathisia therapeutic agent
JPH07252153A (en) * 1995-01-25 1995-10-03 Otsuka Pharmaceut Co Ltd Antiarrhythmic agent
JPH07285940A (en) * 1988-08-10 1995-10-31 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPH07304740A (en) * 1995-03-16 1995-11-21 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JP2011520815A (en) * 2008-05-09 2011-07-21 エモリー・ユニバーシテイ NMDA receptor antagonist for the treatment of neuropsychiatric disorders

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3026331A1 (en) * 1980-07-11 1982-02-18 Basf Ag, 6700 Ludwigshafen INDANONE OXYALKYL PIPERAZINE DERIVATIVES, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATION CONTAINING THEM
DE3101502A1 (en) * 1981-01-19 1982-08-26 Basf Ag, 6700 Ludwigshafen PHENYLPIPERAZINE DERIVATIVES OF HETARYLPHENOLS AND HETARYLANILINES, THEIR PRODUCTION AND THEIR CONTAINING THERAPEUTIC AGENTS
DE3424685A1 (en) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg NEW SUBSTITUTED PHENYLPIPERAZINYL PROPANOLS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
DE3721260A1 (en) * 1987-06-27 1989-01-12 Beiersdorf Ag NEW INDOLYL PROPANOLS, METHOD FOR THEIR PRODUCTION AND THEIR USE, AND PREPARATIONS CONTAINING THE COMPOUNDS

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1424571A (en) * 1921-10-19 1922-08-01 Kaufmann Siegfried Henry Manicure case

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1424571A (en) * 1921-10-19 1922-08-01 Kaufmann Siegfried Henry Manicure case

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56122351A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Oxyindole derivative
JPS6341387B2 (en) * 1980-02-29 1988-08-17 Otsuka Pharma Co Ltd
JPS56140970A (en) * 1980-04-04 1981-11-04 Ronza Chem:Kk Preparation of indole derivative
JPS62135423A (en) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd Improver for hypoxia
JPS63290821A (en) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd Antiarrhythmic
JPH07285940A (en) * 1988-08-10 1995-10-31 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPH04352723A (en) * 1991-05-31 1992-12-07 Otsuka Pharmaceut Co Ltd Akathisia therapeutic agent
JPH07252153A (en) * 1995-01-25 1995-10-03 Otsuka Pharmaceut Co Ltd Antiarrhythmic agent
JPH07304740A (en) * 1995-03-16 1995-11-21 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JP2987484B2 (en) * 1995-03-16 1999-12-06 大塚製薬 株式会社 Method for producing carbostyril derivative
JP2011520815A (en) * 2008-05-09 2011-07-21 エモリー・ユニバーシテイ NMDA receptor antagonist for the treatment of neuropsychiatric disorders

Also Published As

Publication number Publication date
JPS6353162B2 (en) 1988-10-21
ZA792783B (en) 1980-06-25
DE2824677A1 (en) 1979-12-20

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