JPS54132544A - Novel anthranilic acid derivative - Google Patents

Novel anthranilic acid derivative

Info

Publication number
JPS54132544A
JPS54132544A JP3188478A JP3188478A JPS54132544A JP S54132544 A JPS54132544 A JP S54132544A JP 3188478 A JP3188478 A JP 3188478A JP 3188478 A JP3188478 A JP 3188478A JP S54132544 A JPS54132544 A JP S54132544A
Authority
JP
Japan
Prior art keywords
acid
formula
anthranilic acid
reaction
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3188478A
Other languages
Japanese (ja)
Other versions
JPS6019738B2 (en
Inventor
Kanji Noda
Akira Nakagawa
Toshiharu Motomura
Masayoshi Tsuji
Hidetoshi Amano
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP3188478A priority Critical patent/JPS6019738B2/en
Publication of JPS54132544A publication Critical patent/JPS54132544A/en
Publication of JPS6019738B2 publication Critical patent/JPS6019738B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:Anthranilic acid derivatives of formula I (X is lower lakyl having 1 or 2 substituted groups is arbitrary positions, power alkoxy, nitro; R1 is H, lower alkyl; R2 is benzoyl substituted with 1W3 methoxy groups, cinnamoyl). EXANPLE:Methyl N-(3,4,5-trimethoxybenzoyl)-4,5-dimethoxyanthranilate.
USE: Medicines having antiallergic actions.
PREPARATION: The reaction between an anthranilic acid dericative of formula II and a reactive derivative of benzoic acid of formula III, as acid halide or acid anhydride, is conducted in an organic solvent as tetrahydrofuran to form a compound of formula I. When the acid halide is employed, the combination of an acid acceptor accelerates the reaction.
COPYRIGHT: (C)1979,JPO&Japio
JP3188478A 1978-03-20 1978-03-20 Novel anthranilic acid derivative Expired JPS6019738B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3188478A JPS6019738B2 (en) 1978-03-20 1978-03-20 Novel anthranilic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3188478A JPS6019738B2 (en) 1978-03-20 1978-03-20 Novel anthranilic acid derivative

Publications (2)

Publication Number Publication Date
JPS54132544A true JPS54132544A (en) 1979-10-15
JPS6019738B2 JPS6019738B2 (en) 1985-05-17

Family

ID=12343453

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3188478A Expired JPS6019738B2 (en) 1978-03-20 1978-03-20 Novel anthranilic acid derivative

Country Status (1)

Country Link
JP (1) JPS6019738B2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2799427A1 (en) 2006-07-05 2014-11-05 Fibrotech Therapeutics PTY LTD Therapeutic compounds
US9951087B2 (en) 2009-10-22 2018-04-24 Fibrotech Therapeutics Pty Ltd Fused ring analogues of anti-fibrotic agents
US11014873B2 (en) 2017-02-03 2021-05-25 Certa Therapeutics Pty Ltd. Anti-fibrotic compounds

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2799427A1 (en) 2006-07-05 2014-11-05 Fibrotech Therapeutics PTY LTD Therapeutic compounds
US9561201B2 (en) 2006-07-05 2017-02-07 Fibrotech Therapeutics Pty Ltd Therapeutic compounds
US9951087B2 (en) 2009-10-22 2018-04-24 Fibrotech Therapeutics Pty Ltd Fused ring analogues of anti-fibrotic agents
US11014873B2 (en) 2017-02-03 2021-05-25 Certa Therapeutics Pty Ltd. Anti-fibrotic compounds
US11603349B2 (en) 2017-02-03 2023-03-14 Certa Therapeutics Pty Ltd Anti-fibrotic compounds

Also Published As

Publication number Publication date
JPS6019738B2 (en) 1985-05-17

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