JPS5629548A - Omega-aminoalkoxystilbenes and their acid addition salts - Google Patents

Omega-aminoalkoxystilbenes and their acid addition salts

Info

Publication number
JPS5629548A
JPS5629548A JP10421879A JP10421879A JPS5629548A JP S5629548 A JPS5629548 A JP S5629548A JP 10421879 A JP10421879 A JP 10421879A JP 10421879 A JP10421879 A JP 10421879A JP S5629548 A JPS5629548 A JP S5629548A
Authority
JP
Japan
Prior art keywords
formula
aminoalkoxystilbenes
acid addition
addition salts
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10421879A
Other languages
English (en)
Other versions
JPS6227062B2 (ja
Inventor
Ryoji Kikumoto
Akihiro Tobe
Jiichi Fukami
Mitsuo Egawa
Kunihiro Ninomiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP10421879A priority Critical patent/JPS5629548A/ja
Priority to DE8080104513T priority patent/DE3062037D1/de
Priority to US06/173,476 priority patent/US4310534A/en
Priority to EP80104513A priority patent/EP0024567B1/en
Priority to HU80802022A priority patent/HU180375B/hu
Priority to CA000358266A priority patent/CA1151169A/en
Publication of JPS5629548A publication Critical patent/JPS5629548A/ja
Publication of JPS6227062B2 publication Critical patent/JPS6227062B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP10421879A 1979-08-16 1979-08-16 Omega-aminoalkoxystilbenes and their acid addition salts Granted JPS5629548A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP10421879A JPS5629548A (en) 1979-08-16 1979-08-16 Omega-aminoalkoxystilbenes and their acid addition salts
DE8080104513T DE3062037D1 (en) 1979-08-16 1980-07-30 2-(4-aminobutoxy)stilbenes and pharmaceutical compositions comprising these compounds
US06/173,476 US4310534A (en) 1979-08-16 1980-07-30 Pharmaceutically active 2-(4-aminobutoxy)stilbenes
EP80104513A EP0024567B1 (en) 1979-08-16 1980-07-30 2-(4-aminobutoxy)stilbenes and pharmaceutical compositions comprising these compounds
HU80802022A HU180375B (en) 1979-08-16 1980-08-14 Process for producing pharmaceutically active 2-bracket-4-amino-butoxy-bracket closed-stylbene derivatives
CA000358266A CA1151169A (en) 1979-08-16 1980-08-14 Pharmaceutically active 2-(4-aminobutoxy) stilbenes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10421879A JPS5629548A (en) 1979-08-16 1979-08-16 Omega-aminoalkoxystilbenes and their acid addition salts

Publications (2)

Publication Number Publication Date
JPS5629548A true JPS5629548A (en) 1981-03-24
JPS6227062B2 JPS6227062B2 (ja) 1987-06-12

Family

ID=14374812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10421879A Granted JPS5629548A (en) 1979-08-16 1979-08-16 Omega-aminoalkoxystilbenes and their acid addition salts

Country Status (6)

Country Link
US (1) US4310534A (ja)
EP (1) EP0024567B1 (ja)
JP (1) JPS5629548A (ja)
CA (1) CA1151169A (ja)
DE (1) DE3062037D1 (ja)
HU (1) HU180375B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01128893U (ja) * 1988-02-26 1989-09-01

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105552B2 (en) 1998-05-08 2006-09-12 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6331633B1 (en) 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6624197B1 (en) 1998-05-08 2003-09-23 Calyx Therapeutics, Inc. Diphenylethylene compounds
US6245814B1 (en) 1998-05-08 2001-06-12 Calyx Therapeutics, Inc. Diphenylethylene compounds
US7407978B2 (en) 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US6525093B1 (en) * 1999-11-08 2003-02-25 Calyx Therapeutics Inc. Compounds to treat diabetes and associated conditions
US20020002200A1 (en) * 2000-02-04 2002-01-03 Bishwagit Nag Novel diphenylethylene compounds
US20080108825A1 (en) * 1999-11-08 2008-05-08 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1152108A (en) * 1966-12-28 1969-05-14 Kyorin Seiyaku Kk Novel Piperazine Derivatives, and processes for their preparation
US3555071A (en) * 1967-10-17 1971-01-12 Upjohn Co Isocyanatostilbenes
BE754405A (fr) * 1969-08-05 1971-02-04 Thomae Gmbh Dr K Nouveaux beta-aryl-2-aminoalcoxystyrenes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01128893U (ja) * 1988-02-26 1989-09-01

Also Published As

Publication number Publication date
DE3062037D1 (en) 1983-03-24
JPS6227062B2 (ja) 1987-06-12
CA1151169A (en) 1983-08-02
US4310534A (en) 1982-01-12
EP0024567B1 (en) 1983-02-16
EP0024567A1 (en) 1981-03-11
HU180375B (en) 1983-02-28

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