JPS56158788A - Cephalosporin compound for oral use - Google Patents

Cephalosporin compound for oral use

Info

Publication number
JPS56158788A
JPS56158788A JP6305680A JP6305680A JPS56158788A JP S56158788 A JPS56158788 A JP S56158788A JP 6305680 A JP6305680 A JP 6305680A JP 6305680 A JP6305680 A JP 6305680A JP S56158788 A JPS56158788 A JP S56158788A
Authority
JP
Japan
Prior art keywords
compound
formula
amino
carboxylic acid
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6305680A
Other languages
Japanese (ja)
Inventor
Hideo Nakao
Shinichi Sugawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP6305680A priority Critical patent/JPS56158788A/en
Publication of JPS56158788A publication Critical patent/JPS56158788A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A cephem compound (syn isomer) of formula I (R is lower alkyl other than t-butyl) and a salt thereof.
EXAMPLE: Isobutyryloxymethyl 7-[ 2-( 2-amino -4- thiazolyl )-2-methoxyiminoacetmido]3-methyl-3-cephem-4-carboxylate.
USE: An antimicrobial agent, readily absorbable from the digestive tract, and capable of giving a high concentration of a carboxylic acid type compound in blood due to the rapid decomposition of the ester part at the 4-position into the carboxylic acid in the living body.
PROCESS: A compound of formula II or an acid addition salt thereof is reacted with a carboxylic acid of formula III (X is amino or protected amino) or a reactive derivative thereof to give a compound of formula IV, and the group (X) is converted into an amino group to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP6305680A 1980-05-13 1980-05-13 Cephalosporin compound for oral use Pending JPS56158788A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6305680A JPS56158788A (en) 1980-05-13 1980-05-13 Cephalosporin compound for oral use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6305680A JPS56158788A (en) 1980-05-13 1980-05-13 Cephalosporin compound for oral use

Publications (1)

Publication Number Publication Date
JPS56158788A true JPS56158788A (en) 1981-12-07

Family

ID=13218291

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6305680A Pending JPS56158788A (en) 1980-05-13 1980-05-13 Cephalosporin compound for oral use

Country Status (1)

Country Link
JP (1) JPS56158788A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01265093A (en) * 1988-10-12 1989-10-23 Sankyo Co Ltd Cephalosporin compound for oral use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01265093A (en) * 1988-10-12 1989-10-23 Sankyo Co Ltd Cephalosporin compound for oral use

Similar Documents

Publication Publication Date Title
JPS5452096A (en) Cephem compound, its preparation and bacteriostatic agent containing the same
JPS5686187A (en) 7-acylamino-3-vinylcephalosporanic acid derivative and its preparation
IL57392A (en) 7-(2-(2-aminothiazolyl)-(2-methoxyimino))acetamido-3-(di-and tetrahydrotriazinyl)thiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
JPS56125392A (en) Cepham and cephem compound and preparation thereof
JPS56118085A (en) 2-methylcephalosporin derivative and its preparation
JPS56158788A (en) Cephalosporin compound for oral use
JPS559060A (en) Thia(oxa)zolidinecarboxylic acid derivative and its prepatation
JPS5762287A (en) Cephalosporin compound for oral administration
JPS5246093A (en) 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof
JPS57136586A (en) Cephalosporin derivative and its preparation
JPS55160782A (en) Cephalosporin compound for oral administration
JPS5616491A (en) Cephalosporin analog
JPS568391A (en) Cephalosporin compound for oral use
JPS56122362A (en) Tetrazole derivative, its preparation, and antiulcer agent containing the same
JPS55149240A (en) Hydroxybenzoic acid derivative and its acid addition salt
JPS56120687A (en) Cephalosporin derivative and its preparation
JPS57165389A (en) Novel penicillin and cephalosporin compound
JPS57203035A (en) Carboxylic acid ester
JPS577418A (en) Cephalosporin agent composition for oral administration
DE3374316D1 (en) Penicillin derivatives
JPS56128787A (en) Cephalosporin derivative and its preparation
JPS56139493A (en) Cephalosporin compound and its preparation
JPS5572195A (en) Novel cephalosporin and antibacterial comprising it as active constituent
JPS57139082A (en) Acid addition salt of cephalosporin derivative
JPS55149288A (en) Cephalosporanic acid derivative having pyrimidine or its salt