JPS577418A - Cephalosporin agent composition for oral administration - Google Patents
Cephalosporin agent composition for oral administrationInfo
- Publication number
- JPS577418A JPS577418A JP8174780A JP8174780A JPS577418A JP S577418 A JPS577418 A JP S577418A JP 8174780 A JP8174780 A JP 8174780A JP 8174780 A JP8174780 A JP 8174780A JP S577418 A JPS577418 A JP S577418A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- solid organic
- acid
- oral administration
- organic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: The titled composition having improved absorbability from the digestive organs, obtained by blending a certain cephalosporin type compound with a solid organic acid.
CONSTITUTION: Pivaloyloxymethyl 7β-[ 2-( 2-aminothiazole-4-yl )acetamido ]-3-{[ [ 1-(2-dimethylaminoethyl)-1H-tetrazole-5-yl ]thio]methyl}-ceph-3-em-4-carboxylate is blended with a solid organic acid(e.g., tartaric acid, citric acid) in one to five times moles of the carboxylate. The above-mentioned compound has more improved absorbability in oral administration than a corresponding free carboxylic acid compound, but it is not enough. The compound is abosrbed quickly from the digetive organs by the addition of the solid organic acid, and after absorption, the compound is hydrolyzed by enzymes in a living body, to give a corresponding free carboxylic acid compound, which exhibits antibacterial actions on Gram-positive and Gram-negative bacteria and their resistant bacteria.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8174780A JPS577418A (en) | 1980-06-16 | 1980-06-16 | Cephalosporin agent composition for oral administration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8174780A JPS577418A (en) | 1980-06-16 | 1980-06-16 | Cephalosporin agent composition for oral administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS577418A true JPS577418A (en) | 1982-01-14 |
Family
ID=13755022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8174780A Pending JPS577418A (en) | 1980-06-16 | 1980-06-16 | Cephalosporin agent composition for oral administration |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS577418A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6324218A (en) * | 1986-06-18 | 1988-02-01 | インターナショナル・ビジネス・マシーンズ・コーポレーション | Voltage control type light modulator |
| JPS63183533A (en) * | 1986-09-10 | 1988-07-28 | Toyama Chem Co Ltd | Oral cephalosporin composition |
-
1980
- 1980-06-16 JP JP8174780A patent/JPS577418A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6324218A (en) * | 1986-06-18 | 1988-02-01 | インターナショナル・ビジネス・マシーンズ・コーポレーション | Voltage control type light modulator |
| JPH0350247B2 (en) * | 1986-06-18 | 1991-08-01 | Intaanashonaru Bijinesu Mashiinzu Corp | |
| JPS63183533A (en) * | 1986-09-10 | 1988-07-28 | Toyama Chem Co Ltd | Oral cephalosporin composition |
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