JPS5640683A - Cephalosporin analogue - Google Patents

Cephalosporin analogue

Info

Publication number
JPS5640683A
JPS5640683A JP11672079A JP11672079A JPS5640683A JP S5640683 A JPS5640683 A JP S5640683A JP 11672079 A JP11672079 A JP 11672079A JP 11672079 A JP11672079 A JP 11672079A JP S5640683 A JPS5640683 A JP S5640683A
Authority
JP
Japan
Prior art keywords
formula
acid
compound
gram
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11672079A
Other languages
Japanese (ja)
Other versions
JPH0121149B2 (en
Inventor
Tadashi Hirata
Takehiro Ogasa
Chikahiro Urakawa
Akira Sato
Shigeru Kobayashi
Kiyoshi Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP11672079A priority Critical patent/JPS5640683A/en
Priority to ES495035A priority patent/ES495035A0/en
Priority to NO802713A priority patent/NO802713L/en
Priority to DK389080A priority patent/DK389080A/en
Priority to EP80105492A priority patent/EP0025602B1/en
Priority to DE8080105492T priority patent/DE3069832D1/en
Priority to AU62356/80A priority patent/AU6235680A/en
Priority to CA000360255A priority patent/CA1178957A/en
Publication of JPS5640683A publication Critical patent/JPS5640683A/en
Publication of JPH0121149B2 publication Critical patent/JPH0121149B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (X is acyl; R is protected or unprotected carboxyl).
EXAMPLE: (±)-cis-7β-[ 2-( 2-Amino-4-thiazolyl )-2-syn-methoxyiminoacetamido ]- 4α-hydroxy-1-azebicyclo[4,2,0]oct-2-en-8-one-2-carboxylic acid.
USE: Fungicide for various infectious diseases. Useful as a component of disinfectant. Exhibits strong antibacterial activity against both Gram-positive and Gram-negative bacteria.
PROCESS: The compound of formula I is prepared by acylating a compound of formula II with a carboxylic acid of formula X2CO2H (X2 is X1 or protected X1) or its reactive derivative (e.g. acid halide, acid anhydride, mixed acid anhydride, active ester, acid azide, etc.), and if necessary, eliminating the protecting group of X2 and CO2R1.
COPYRIGHT: (C)1981,JPO&Japio
JP11672079A 1979-09-13 1979-09-13 Cephalosporin analogue Granted JPS5640683A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP11672079A JPS5640683A (en) 1979-09-13 1979-09-13 Cephalosporin analogue
ES495035A ES495035A0 (en) 1979-09-13 1980-09-12 A PROCEDURE FOR THE PRODUCTION OF CEPHALOSPORIN ANALOGS.
NO802713A NO802713L (en) 1979-09-13 1980-09-12 PROCEDURE FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE CEPHALOSPORIN ANALOGUE CARBACEFEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS
DK389080A DK389080A (en) 1979-09-13 1980-09-12 PROCEDURE FOR PREPARING RACEMIC OR OPTICALLY ACTIVE CEPHALOSPORIN ANALOGUE CARBACEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPABLE SALTS THEREOF
EP80105492A EP0025602B1 (en) 1979-09-13 1980-09-12 Acylated cephalosporin analogs, process for their preparation and pharmaceutical compositions comprising them
DE8080105492T DE3069832D1 (en) 1979-09-13 1980-09-12 Acylated cephalosporin analogs, process for their preparation and pharmaceutical compositions comprising them
AU62356/80A AU6235680A (en) 1979-09-13 1980-09-12 Cephalosporin analogs
CA000360255A CA1178957A (en) 1979-09-13 1980-09-15 Cephalosporin analogs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11672079A JPS5640683A (en) 1979-09-13 1979-09-13 Cephalosporin analogue

Publications (2)

Publication Number Publication Date
JPS5640683A true JPS5640683A (en) 1981-04-16
JPH0121149B2 JPH0121149B2 (en) 1989-04-19

Family

ID=14694133

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11672079A Granted JPS5640683A (en) 1979-09-13 1979-09-13 Cephalosporin analogue

Country Status (2)

Country Link
JP (1) JPS5640683A (en)
AU (1) AU6235680A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56152479A (en) * 1980-04-26 1981-11-26 Kyowa Hakko Kogyo Co Ltd Optically active cephalosporin analog

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56152479A (en) * 1980-04-26 1981-11-26 Kyowa Hakko Kogyo Co Ltd Optically active cephalosporin analog
JPH0240669B2 (en) * 1980-04-26 1990-09-12 Kyowa Hakko Kogyo Kk

Also Published As

Publication number Publication date
AU6235680A (en) 1981-03-19
JPH0121149B2 (en) 1989-04-19

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