JPS5640683A - Cephalosporin analogue - Google Patents
Cephalosporin analogueInfo
- Publication number
- JPS5640683A JPS5640683A JP11672079A JP11672079A JPS5640683A JP S5640683 A JPS5640683 A JP S5640683A JP 11672079 A JP11672079 A JP 11672079A JP 11672079 A JP11672079 A JP 11672079A JP S5640683 A JPS5640683 A JP S5640683A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- acid
- compound
- gram
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound of formula I (X is acyl; R is protected or unprotected carboxyl).
EXAMPLE: (±)-cis-7β-[ 2-( 2-Amino-4-thiazolyl )-2-syn-methoxyiminoacetamido ]- 4α-hydroxy-1-azebicyclo[4,2,0]oct-2-en-8-one-2-carboxylic acid.
USE: Fungicide for various infectious diseases. Useful as a component of disinfectant. Exhibits strong antibacterial activity against both Gram-positive and Gram-negative bacteria.
PROCESS: The compound of formula I is prepared by acylating a compound of formula II with a carboxylic acid of formula X2CO2H (X2 is X1 or protected X1) or its reactive derivative (e.g. acid halide, acid anhydride, mixed acid anhydride, active ester, acid azide, etc.), and if necessary, eliminating the protecting group of X2 and CO2R1.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11672079A JPS5640683A (en) | 1979-09-13 | 1979-09-13 | Cephalosporin analogue |
ES495035A ES495035A0 (en) | 1979-09-13 | 1980-09-12 | A PROCEDURE FOR THE PRODUCTION OF CEPHALOSPORIN ANALOGS. |
NO802713A NO802713L (en) | 1979-09-13 | 1980-09-12 | PROCEDURE FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE CEPHALOSPORIN ANALOGUE CARBACEFEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS |
DK389080A DK389080A (en) | 1979-09-13 | 1980-09-12 | PROCEDURE FOR PREPARING RACEMIC OR OPTICALLY ACTIVE CEPHALOSPORIN ANALOGUE CARBACEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPABLE SALTS THEREOF |
EP80105492A EP0025602B1 (en) | 1979-09-13 | 1980-09-12 | Acylated cephalosporin analogs, process for their preparation and pharmaceutical compositions comprising them |
DE8080105492T DE3069832D1 (en) | 1979-09-13 | 1980-09-12 | Acylated cephalosporin analogs, process for their preparation and pharmaceutical compositions comprising them |
AU62356/80A AU6235680A (en) | 1979-09-13 | 1980-09-12 | Cephalosporin analogs |
CA000360255A CA1178957A (en) | 1979-09-13 | 1980-09-15 | Cephalosporin analogs |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11672079A JPS5640683A (en) | 1979-09-13 | 1979-09-13 | Cephalosporin analogue |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5640683A true JPS5640683A (en) | 1981-04-16 |
JPH0121149B2 JPH0121149B2 (en) | 1989-04-19 |
Family
ID=14694133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11672079A Granted JPS5640683A (en) | 1979-09-13 | 1979-09-13 | Cephalosporin analogue |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS5640683A (en) |
AU (1) | AU6235680A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56152479A (en) * | 1980-04-26 | 1981-11-26 | Kyowa Hakko Kogyo Co Ltd | Optically active cephalosporin analog |
-
1979
- 1979-09-13 JP JP11672079A patent/JPS5640683A/en active Granted
-
1980
- 1980-09-12 AU AU62356/80A patent/AU6235680A/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56152479A (en) * | 1980-04-26 | 1981-11-26 | Kyowa Hakko Kogyo Co Ltd | Optically active cephalosporin analog |
JPH0240669B2 (en) * | 1980-04-26 | 1990-09-12 | Kyowa Hakko Kogyo Kk |
Also Published As
Publication number | Publication date |
---|---|
AU6235680A (en) | 1981-03-19 |
JPH0121149B2 (en) | 1989-04-19 |
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