JPS56120687A - Cephalosporin derivative and its preparation - Google Patents
Cephalosporin derivative and its preparationInfo
- Publication number
- JPS56120687A JPS56120687A JP2480380A JP2480380A JPS56120687A JP S56120687 A JPS56120687 A JP S56120687A JP 2480380 A JP2480380 A JP 2480380A JP 2480380 A JP2480380 A JP 2480380A JP S56120687 A JPS56120687 A JP S56120687A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compounds
- bacteria
- gram
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A cephalosporin derivative of formula I (R is 2W4C lower alkyl) and its salt.
EXAMPLE: 7-( D- 2-Propionyloxy- 2-phenylacetamido )-3- methylcept-3- em-4-carboxlic acid.
USE: Antibiotic substance. Effective as a remedy for the infectious diseases of respiratory system and urinary tract caused by bacteria. Active to Gram-positive bacteria, Gram-negative bacteria, and their resistant variants. It has low toxicity and high absorption efficiency through digestive tracts.
PROCESS: The compound of formula I can be prepared by reacting a 2-acyloxy-2- phenylacetic acid of formula II with the compound of formula III or its salt by conventional manner. Although both compounds of formula II and formula III can be used in the form of free compounds, it is preferable to use one or both compounds as reactive derivatives for amidation.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2480380A JPS56120687A (en) | 1980-02-28 | 1980-02-28 | Cephalosporin derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2480380A JPS56120687A (en) | 1980-02-28 | 1980-02-28 | Cephalosporin derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56120687A true JPS56120687A (en) | 1981-09-22 |
Family
ID=12148344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2480380A Pending JPS56120687A (en) | 1980-02-28 | 1980-02-28 | Cephalosporin derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56120687A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996001242A1 (en) * | 1994-07-06 | 1996-01-18 | Basf Aktiengesellschaft | Process and catalyst for the selective hydrogenation of butine diol to butene diol |
-
1980
- 1980-02-28 JP JP2480380A patent/JPS56120687A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996001242A1 (en) * | 1994-07-06 | 1996-01-18 | Basf Aktiengesellschaft | Process and catalyst for the selective hydrogenation of butine diol to butene diol |
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