JPS56120687A - Cephalosporin derivative and its preparation - Google Patents

Cephalosporin derivative and its preparation

Info

Publication number
JPS56120687A
JPS56120687A JP2480380A JP2480380A JPS56120687A JP S56120687 A JPS56120687 A JP S56120687A JP 2480380 A JP2480380 A JP 2480380A JP 2480380 A JP2480380 A JP 2480380A JP S56120687 A JPS56120687 A JP S56120687A
Authority
JP
Japan
Prior art keywords
formula
compounds
bacteria
gram
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2480380A
Other languages
Japanese (ja)
Inventor
Yoshinobu Yoshimura
Sunao Hamaguchi
Senji Kakeya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP2480380A priority Critical patent/JPS56120687A/en
Publication of JPS56120687A publication Critical patent/JPS56120687A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A cephalosporin derivative of formula I (R is 2W4C lower alkyl) and its salt.
EXAMPLE: 7-( D- 2-Propionyloxy- 2-phenylacetamido )-3- methylcept-3- em-4-carboxlic acid.
USE: Antibiotic substance. Effective as a remedy for the infectious diseases of respiratory system and urinary tract caused by bacteria. Active to Gram-positive bacteria, Gram-negative bacteria, and their resistant variants. It has low toxicity and high absorption efficiency through digestive tracts.
PROCESS: The compound of formula I can be prepared by reacting a 2-acyloxy-2- phenylacetic acid of formula II with the compound of formula III or its salt by conventional manner. Although both compounds of formula II and formula III can be used in the form of free compounds, it is preferable to use one or both compounds as reactive derivatives for amidation.
COPYRIGHT: (C)1981,JPO&Japio
JP2480380A 1980-02-28 1980-02-28 Cephalosporin derivative and its preparation Pending JPS56120687A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2480380A JPS56120687A (en) 1980-02-28 1980-02-28 Cephalosporin derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2480380A JPS56120687A (en) 1980-02-28 1980-02-28 Cephalosporin derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS56120687A true JPS56120687A (en) 1981-09-22

Family

ID=12148344

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2480380A Pending JPS56120687A (en) 1980-02-28 1980-02-28 Cephalosporin derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS56120687A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001242A1 (en) * 1994-07-06 1996-01-18 Basf Aktiengesellschaft Process and catalyst for the selective hydrogenation of butine diol to butene diol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001242A1 (en) * 1994-07-06 1996-01-18 Basf Aktiengesellschaft Process and catalyst for the selective hydrogenation of butine diol to butene diol

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