JPS56135418A - Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human - Google Patents
Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from humanInfo
- Publication number
- JPS56135418A JPS56135418A JP4005080A JP4005080A JPS56135418A JP S56135418 A JPS56135418 A JP S56135418A JP 4005080 A JP4005080 A JP 4005080A JP 4005080 A JP4005080 A JP 4005080A JP S56135418 A JPS56135418 A JP S56135418A
- Authority
- JP
- Japan
- Prior art keywords
- coagulation
- xiiifactor
- human
- aqueous solution
- heat treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4005080A JPS56135418A (en) | 1980-03-27 | 1980-03-27 | Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human |
US06/245,971 US4327086A (en) | 1980-03-27 | 1981-03-20 | Process for heat treatment of aqueous solution containing human blood coagulation factor XIII |
EP81102255A EP0037078B1 (en) | 1980-03-27 | 1981-03-25 | Process for heat treatment of aqueous solution containing human blood coagulation factor xiii |
DE8181102255T DE3162578D1 (en) | 1980-03-27 | 1981-03-25 | Process for heat treatment of aqueous solution containing human blood coagulation factor xiii |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4005080A JPS56135418A (en) | 1980-03-27 | 1980-03-27 | Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56135418A true JPS56135418A (en) | 1981-10-22 |
JPS6236493B2 JPS6236493B2 (ja) | 1987-08-07 |
Family
ID=12570076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4005080A Granted JPS56135418A (en) | 1980-03-27 | 1980-03-27 | Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human |
Country Status (4)
Country | Link |
---|---|
US (1) | US4327086A (ja) |
EP (1) | EP0037078B1 (ja) |
JP (1) | JPS56135418A (ja) |
DE (1) | DE3162578D1 (ja) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5874617A (ja) * | 1981-10-28 | 1983-05-06 | Green Cross Corp:The | 人由来血液凝固第7因子含有水溶液の加熱処理方法 |
JPH08245418A (ja) * | 1995-03-09 | 1996-09-24 | Behringwerke Ag | 安定なトランスグルタミナーゼ製剤およびそれらを製造する方法 |
JP2002234531A (ja) * | 2001-02-09 | 2002-08-20 | Asahi Printing Co Ltd | 包装用箱と物品収容枠 |
JP2009007041A (ja) * | 2007-06-28 | 2009-01-15 | Sigma Shigyo Kk | 包装容器 |
JP2009062384A (ja) * | 2008-10-22 | 2009-03-26 | Csl Behring Gmbh | ヒト血液凝固第xiii因子の安定化された水性液製剤 |
CN105879038A (zh) * | 2016-05-27 | 2016-08-24 | 成都蓉生药业有限责任公司 | 一种制备人凝血酶原复合物的干热处理稳定剂及其用途 |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3043857A1 (de) * | 1980-11-21 | 1982-07-08 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ii und vii |
DE3045153A1 (de) * | 1980-11-29 | 1982-07-08 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ix und x |
JPS57140724A (en) | 1981-02-25 | 1982-08-31 | Green Cross Corp:The | Heat-treatment of aqueous solution containing cold insoluble globulin |
US4495278A (en) * | 1981-04-27 | 1985-01-22 | Baxter Travenol Laboratories, Inc. | Process for making novel blood clotting enzyme compositions |
US4845074A (en) * | 1982-05-13 | 1989-07-04 | Cedars Sinai Medical Center | Heat treatment of Factor VIII |
US4456590B2 (en) * | 1981-11-02 | 1989-05-30 | Heat treatment of lyphilized blood clotting factor viii concentrate | |
US4556558A (en) * | 1982-05-13 | 1985-12-03 | Cedars-Sinai Medical Center | Treatment of factor VIII concentrate to minimize the affect of undesirable microorganisms |
DE3230849A1 (de) * | 1982-08-19 | 1984-02-23 | Behringwerke Ag, 3550 Marburg | Pasteurisiertes human-fibrinogen (hf) und verfahren zu dessen herstellung |
JPS5967228A (ja) * | 1982-10-07 | 1984-04-16 | Green Cross Corp:The | 寒冷不溶性グロブリンの凍結乾燥方法 |
JPS59104326A (ja) * | 1982-12-04 | 1984-06-16 | Toyo Jozo Co Ltd | マクロライド抗生物質の安定な経口用製剤および安定化法 |
US4585654A (en) * | 1983-04-29 | 1986-04-29 | Armour Pharmaceutical Co. | Process for pasteurizing fibronectin |
US4727027A (en) * | 1983-05-02 | 1988-02-23 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
US5176921A (en) * | 1983-05-02 | 1993-01-05 | Diamond Scientific Co. | Method of blood component decontamination by glucose addition |
AT382078B (de) * | 1983-05-31 | 1987-01-12 | Immuno Ag | Verfahren zur herstellung von praeparationen aus menschlichem blutplasma |
DE3330770A1 (de) * | 1983-08-26 | 1985-03-14 | Behringwerke Ag, 3550 Marburg | Verfahren zur pasteurisierung von humanplasma |
US5281579A (en) * | 1984-03-23 | 1994-01-25 | Baxter International Inc. | Purified virus-free hemoglobin solutions and method for making same |
DE3419581A1 (de) * | 1984-05-25 | 1985-11-28 | Behringwerke Ag, 3550 Marburg | Verfahren zur gewinnung einer faktor xiii-praeparation sowie ihre verwendung |
JPH0669961B2 (ja) * | 1984-09-25 | 1994-09-07 | 株式会社ミドリ十字 | 免疫グロブリンの加熱処理方法 |
JPH0825902B2 (ja) * | 1985-02-21 | 1996-03-13 | 株式会社ミドリ十字 | γ−グロブリンの加熱処理方法 |
WO1987005220A1 (en) * | 1986-03-10 | 1987-09-11 | Rubinstein Alan I | A method for treating gammaglobulin |
DE3622642A1 (de) * | 1986-07-05 | 1988-01-14 | Behringwerke Ag | Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung |
IL86417A (en) * | 1987-05-22 | 1992-09-06 | Armour Pharma | Process for the inactivation of pathogens in biological or pharmaceutical material by mixing with aqueous solution containing a sugar(alcohol)and neutral salts as stabilizers |
EP0357724B1 (en) * | 1988-02-18 | 1992-12-02 | Baxter International Inc. | Stabilized heparin solution |
CA1331133C (en) * | 1988-03-01 | 1994-08-02 | Michael Jon Pikal | Pharmaceutical growth hormone formulations |
DE3829524A1 (de) * | 1988-08-31 | 1990-03-01 | Behringwerke Ag | Verwendung von transglutaminasen als immunsuppressiva |
JPH0650999B2 (ja) * | 1988-09-12 | 1994-07-06 | 日本商事株式会社 | 血液凝固因子安定化法 |
FR2650508A1 (fr) * | 1989-08-01 | 1991-02-08 | Fondation Nale Transfusion San | Colle pasteurisee pour reunir des tissus humain ou animal |
DE3939346A1 (de) * | 1989-11-29 | 1991-06-06 | Behringwerke Ag | Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide |
JPH03240738A (ja) * | 1990-02-20 | 1991-10-28 | Hoechst Japan Ltd | 糖尿病性壊疽治療剤 |
JPH04507108A (ja) * | 1990-05-07 | 1992-12-10 | バクスター、インターナショナル、インコーポレイテッド | 安定化されたヘパリン溶液 |
JP3337488B2 (ja) * | 1992-03-06 | 2002-10-21 | アベンティス ファーマ株式会社 | 切迫流産治療剤 |
AT402788B (de) * | 1993-08-03 | 1997-08-25 | Immuno Ag | Virussichere blutgerinnungsfaktor xiii-präparation |
GB9418092D0 (en) * | 1994-09-08 | 1994-10-26 | Red Cross Found Cent Lab Blood | Organic compounds |
JPH08333277A (ja) * | 1995-06-05 | 1996-12-17 | Hoechst Japan Ltd | ヒト血液凝固第xiii因子の安定化された水性液製剤 |
RU2244556C2 (ru) | 1999-02-22 | 2005-01-20 | Юниверсити Оф Коннектикут | Новые не содержащие альбумин составы фактора viii |
US7297716B2 (en) * | 2000-10-23 | 2007-11-20 | Shanbrom Technologies, Llc | Enhanced production of blood components, blood cells and plasma without freezing |
US6881731B1 (en) * | 2000-10-23 | 2005-04-19 | Shanbrom Technologies, Llc | Enhancers for microbiological disinfection |
US7411006B2 (en) * | 2000-10-23 | 2008-08-12 | Shanbrom Technologies, Llc | Enhanced production of blood clotting factors and fibrin fabric |
US8389687B2 (en) | 2000-10-23 | 2013-03-05 | Shanbrom Technologies, Llc | Polyvinylpyrrolidone cryoprecipitate extraction of clotting factors |
MXPA03007069A (es) * | 2001-02-07 | 2004-10-15 | Shanbrom Tech Llc | Acido carboxilico tal como acido citrico para desinfectar o mejorar la produccion de productos sanguineos tales como el plasma, crioprecipitado y/o plaqueta. |
EP1532983A1 (en) | 2003-11-18 | 2005-05-25 | ZLB Bioplasma AG | Immunoglobulin preparations having increased stability |
EP2268267B1 (en) * | 2008-04-21 | 2017-06-14 | Novo Nordisk Health Care AG | Dry transglutaminase composition |
JP5779780B2 (ja) | 2008-11-07 | 2015-09-16 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | 第viii因子製剤 |
CA2788863C (en) | 2010-02-04 | 2020-07-07 | Reinhard Franz Bolli | Immunoglobulin preparation |
EP2361636A1 (en) | 2010-02-26 | 2011-08-31 | CSL Behring AG | Immunoglobulin preparation and storage system for an immunoglobulin preparation |
CN102924562B (zh) * | 2012-11-19 | 2014-07-23 | 成都蓉生药业有限责任公司 | 一种人凝血因子ⅷ的干热处理稳定剂及其用途 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51118820A (en) * | 1975-04-08 | 1976-10-19 | Green Cross Corp:The | A process for preparing heat stable macroglobulin |
JPS5359018A (en) * | 1976-11-10 | 1978-05-27 | Green Cross Corp:The | Concentrated xiii-th blood coagulating factor derived from human placentaand its preparation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3904751A (en) * | 1970-12-22 | 1975-09-09 | Behringwerke Ag | Process for isolating a fibrin stabilizing factor from human placenta |
US3931399A (en) * | 1970-12-22 | 1976-01-06 | Behringwerke Aktiengesellschaft | Process for isolating a fibrin-stabilizing factor |
JPS6029687B2 (ja) * | 1978-11-07 | 1985-07-12 | 株式会社ミドリ十字 | ヒト胎盤由来血液凝固第103因子の濃縮液の製造方法 |
DE2916711A1 (de) * | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
-
1980
- 1980-03-27 JP JP4005080A patent/JPS56135418A/ja active Granted
-
1981
- 1981-03-20 US US06/245,971 patent/US4327086A/en not_active Expired - Fee Related
- 1981-03-25 DE DE8181102255T patent/DE3162578D1/de not_active Expired
- 1981-03-25 EP EP81102255A patent/EP0037078B1/en not_active Expired
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51118820A (en) * | 1975-04-08 | 1976-10-19 | Green Cross Corp:The | A process for preparing heat stable macroglobulin |
JPS5359018A (en) * | 1976-11-10 | 1978-05-27 | Green Cross Corp:The | Concentrated xiii-th blood coagulating factor derived from human placentaand its preparation |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5874617A (ja) * | 1981-10-28 | 1983-05-06 | Green Cross Corp:The | 人由来血液凝固第7因子含有水溶液の加熱処理方法 |
JPH0348170B2 (ja) * | 1981-10-28 | 1991-07-23 | Green Cross Corp | |
JPH08245418A (ja) * | 1995-03-09 | 1996-09-24 | Behringwerke Ag | 安定なトランスグルタミナーゼ製剤およびそれらを製造する方法 |
JP2002234531A (ja) * | 2001-02-09 | 2002-08-20 | Asahi Printing Co Ltd | 包装用箱と物品収容枠 |
JP2009007041A (ja) * | 2007-06-28 | 2009-01-15 | Sigma Shigyo Kk | 包装容器 |
JP2009062384A (ja) * | 2008-10-22 | 2009-03-26 | Csl Behring Gmbh | ヒト血液凝固第xiii因子の安定化された水性液製剤 |
CN105879038A (zh) * | 2016-05-27 | 2016-08-24 | 成都蓉生药业有限责任公司 | 一种制备人凝血酶原复合物的干热处理稳定剂及其用途 |
CN105879038B (zh) * | 2016-05-27 | 2020-03-27 | 成都蓉生药业有限责任公司 | 一种制备人凝血酶原复合物的干热处理稳定剂及其用途 |
Also Published As
Publication number | Publication date |
---|---|
EP0037078A2 (en) | 1981-10-07 |
EP0037078A3 (en) | 1982-01-13 |
EP0037078B1 (en) | 1984-03-14 |
DE3162578D1 (en) | 1984-04-19 |
JPS6236493B2 (ja) | 1987-08-07 |
US4327086A (en) | 1982-04-27 |
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