JPS5522475B2 - - Google Patents

Info

Publication number
JPS5522475B2
JPS5522475B2 JP4376376A JP4376376A JPS5522475B2 JP S5522475 B2 JPS5522475 B2 JP S5522475B2 JP 4376376 A JP4376376 A JP 4376376A JP 4376376 A JP4376376 A JP 4376376A JP S5522475 B2 JPS5522475 B2 JP S5522475B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP4376376A
Other languages
Japanese (ja)
Other versions
JPS51136688A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS51136688A publication Critical patent/JPS51136688A/ja
Publication of JPS5522475B2 publication Critical patent/JPS5522475B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP51043763A 1975-04-21 1976-04-19 Anorexia compound or piperazinylpyrazine Granted JPS51136688A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57005275A 1975-04-21 1975-04-21

Publications (2)

Publication Number Publication Date
JPS51136688A JPS51136688A (en) 1976-11-26
JPS5522475B2 true JPS5522475B2 (xx) 1980-06-17

Family

ID=24277994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51043763A Granted JPS51136688A (en) 1975-04-21 1976-04-19 Anorexia compound or piperazinylpyrazine

Country Status (36)

Country Link
JP (1) JPS51136688A (xx)
AR (1) AR210349A1 (xx)
AT (1) AT353795B (xx)
AU (1) AU496854B2 (xx)
BE (1) BE840904A (xx)
BG (1) BG34185A3 (xx)
CA (1) CA1059128A (xx)
CH (1) CH619462A5 (xx)
CS (1) CS195726B2 (xx)
CY (1) CY1090A (xx)
DD (1) DD124599A5 (xx)
DE (1) DE2617205C3 (xx)
DK (1) DK143899C (xx)
EG (1) EG12387A (xx)
ES (4) ES447150A1 (xx)
FI (1) FI62666C (xx)
FR (1) FR2308367A1 (xx)
GB (1) GB1492528A (xx)
GR (1) GR59900B (xx)
HK (1) HK60380A (xx)
HU (1) HU172684B (xx)
IE (1) IE42979B1 (xx)
IL (1) IL49391A (xx)
KE (1) KE3088A (xx)
LU (1) LU74795A1 (xx)
MY (1) MY8100225A (xx)
NL (1) NL167692C (xx)
NO (1) NO146599C (xx)
PH (1) PH12274A (xx)
PL (1) PL99664B1 (xx)
PT (1) PT65027B (xx)
RO (1) RO73278A (xx)
SE (1) SE421695B (xx)
SU (1) SU638260A3 (xx)
YU (1) YU100676A (xx)
ZA (1) ZA762320B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4163849A (en) 1978-03-17 1979-08-07 Merck & Co., Inc. Piperazinylpyrazines
US4252816A (en) * 1979-12-03 1981-02-24 Merck & Co., Inc. Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents
US4339579A (en) 1980-12-29 1982-07-13 American Home Products Corporation 2,6-Bis-(pyrrolopyrazinyl)pyrazines
EP0094498A3 (en) * 1982-05-06 1985-04-03 American Cyanamid Company Antiatherosclerotic 1-piperazine derivatives
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
EP0580465A1 (fr) * 1992-06-25 1994-01-26 Sanofi Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
PL203140B1 (pl) 1997-10-27 2009-08-31 Neurosearch As Pochodna homopiperazyny, kompozycja farmaceutyczna zawierająca te pochodne i zastosowanie tej pochodnej
CN1348449A (zh) 1999-04-26 2002-05-08 神经研究公司 杂芳基二氮杂环烷烃及其制备方法和应用
EE200200453A (et) * 2000-02-16 2003-12-15 Neurogen Corporation Asendatud arüülpürasiinid
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
NZ537629A (en) 2002-07-19 2007-05-31 Biovitrum Ab Novel piperazinyl-pyrazinone derivatives for the treatment of 5-HT2A receptor-related disorders
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2606906A (en) * 1948-10-14 1952-08-12 American Cyanamid Co 1-(2-pyridyl) piperazine and process of preparing same

Also Published As

Publication number Publication date
ES459405A1 (es) 1978-08-16
DE2617205A1 (de) 1976-10-28
NL167692B (nl) 1981-08-17
SE421695B (sv) 1982-01-25
NL167692C (nl) 1982-01-18
PT65027B (en) 1978-04-03
PH12274A (en) 1978-12-12
ATA288376A (de) 1979-05-15
YU100676A (en) 1982-08-31
ZA762320B (en) 1977-11-30
NO146599C (no) 1982-11-03
ES459406A1 (es) 1978-08-16
RO73278A (ro) 1982-09-09
FR2308367B1 (xx) 1979-09-21
BE840904A (fr) 1976-08-16
AR210349A1 (es) 1977-07-29
IL49391A (en) 1979-09-30
GB1492528A (en) 1977-11-23
IL49391A0 (en) 1976-06-30
BG34185A3 (en) 1983-07-15
FR2308367A1 (fr) 1976-11-19
PT65027A (en) 1976-05-01
HK60380A (en) 1980-11-07
ES447150A1 (es) 1977-09-16
ES459407A1 (es) 1978-08-16
SE7604093L (sv) 1976-10-22
FI760978A (xx) 1976-10-22
GR59900B (en) 1978-03-16
AU496854B2 (en) 1978-11-02
EG12387A (en) 1978-12-31
PL99664B1 (pl) 1978-07-31
HU172684B (hu) 1978-11-28
DD124599A5 (xx) 1977-03-02
AT353795B (de) 1979-12-10
DE2617205C3 (de) 1981-01-29
CH619462A5 (en) 1980-09-30
DK143899C (da) 1982-04-13
NO146599B (no) 1982-07-26
IE42979L (en) 1976-10-21
MY8100225A (en) 1981-12-31
AU1296676A (en) 1977-10-20
CS195726B2 (en) 1980-02-29
NL7603800A (nl) 1976-10-25
NO761207L (xx) 1976-10-22
DK143899B (da) 1981-10-26
KE3088A (en) 1980-11-07
FI62666B (fi) 1982-10-29
FI62666C (fi) 1983-02-10
CA1059128A (en) 1979-07-24
CY1090A (en) 1980-12-27
DK164476A (da) 1976-10-22
JPS51136688A (en) 1976-11-26
DE2617205B2 (de) 1980-05-08
LU74795A1 (xx) 1977-02-07
SU638260A3 (ru) 1978-12-15
IE42979B1 (en) 1980-11-19

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