JPS55141457A - Novel benzylidene derivative - Google Patents
Novel benzylidene derivativeInfo
- Publication number
- JPS55141457A JPS55141457A JP4926479A JP4926479A JPS55141457A JP S55141457 A JPS55141457 A JP S55141457A JP 4926479 A JP4926479 A JP 4926479A JP 4926479 A JP4926479 A JP 4926479A JP S55141457 A JPS55141457 A JP S55141457A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- derivative
- formula
- agent
- methanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- RJMIEHBSYVWVIN-LLVKDONJSA-N (2r)-2-[4-(3-oxo-1h-isoindol-2-yl)phenyl]propanoic acid Chemical compound C1=CC([C@H](C(O)=O)C)=CC=C1N1C(=O)C2=CC=CC=C2C1 RJMIEHBSYVWVIN-LLVKDONJSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- MYFLHLBWDURNTB-UHFFFAOYSA-N C1=CC(C(C#N)N)=CCC1=CC1=CC=CC=C1C(O)=O Chemical compound C1=CC(C(C#N)N)=CCC1=CC1=CC=CC=C1C(O)=O MYFLHLBWDURNTB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000002490 anilino group Chemical class [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229960004187 indoprofen Drugs 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- JKNKNWJNCOJPLI-UHFFFAOYSA-N o-phthalaldehydic acid Chemical compound C1=CC=C2C(O)OC(=O)C2=C1 JKNKNWJNCOJPLI-UHFFFAOYSA-N 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4926479A JPS55141457A (en) | 1979-04-19 | 1979-04-19 | Novel benzylidene derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4926479A JPS55141457A (en) | 1979-04-19 | 1979-04-19 | Novel benzylidene derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55141457A true JPS55141457A (en) | 1980-11-05 |
| JPS626543B2 JPS626543B2 (en, 2012) | 1987-02-12 |
Family
ID=12825961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4926479A Granted JPS55141457A (en) | 1979-04-19 | 1979-04-19 | Novel benzylidene derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55141457A (en, 2012) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018159639A1 (ja) * | 2017-02-28 | 2018-09-07 | 武田薬品工業株式会社 | 複素環化合物の製造方法 |
| CN115850154A (zh) * | 2022-12-29 | 2023-03-28 | 山东京卫制药有限公司 | 一种吲哚布芬的制备方法 |
-
1979
- 1979-04-19 JP JP4926479A patent/JPS55141457A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018159639A1 (ja) * | 2017-02-28 | 2018-09-07 | 武田薬品工業株式会社 | 複素環化合物の製造方法 |
| JPWO2018159639A1 (ja) * | 2017-02-28 | 2019-12-26 | 武田薬品工業株式会社 | 複素環化合物の製造方法 |
| CN110753689A (zh) * | 2017-02-28 | 2020-02-04 | 武田药品工业株式会社 | 用于生产杂环化合物的方法 |
| US10710989B2 (en) | 2017-02-28 | 2020-07-14 | Takeda Pharmaceutical Company Limited | Method for producing heterocyclic compound |
| CN110753689B (zh) * | 2017-02-28 | 2024-01-26 | 武田药品工业株式会社 | 用于生产杂环化合物的方法 |
| CN115850154A (zh) * | 2022-12-29 | 2023-03-28 | 山东京卫制药有限公司 | 一种吲哚布芬的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS626543B2 (en, 2012) | 1987-02-12 |
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