JPS55133370A - Pentofuranosylanthracycline*its manufacture and antitumor containing it - Google Patents

Pentofuranosylanthracycline*its manufacture and antitumor containing it

Info

Publication number
JPS55133370A
JPS55133370A JP1015980A JP1015980A JPS55133370A JP S55133370 A JPS55133370 A JP S55133370A JP 1015980 A JP1015980 A JP 1015980A JP 1015980 A JP1015980 A JP 1015980A JP S55133370 A JPS55133370 A JP S55133370A
Authority
JP
Japan
Prior art keywords
compounds
pentofuranosylanthracycline
manufacture
hydrogen atom
aminomethyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1015980A
Other languages
English (en)
Other versions
JPS6321671B2 (ja
Inventor
Katsushineri Jiyuzetsupe
Arukamone Fuederiko
Dei Maruko Aurerio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of JPS55133370A publication Critical patent/JPS55133370A/ja
Publication of JPS6321671B2 publication Critical patent/JPS6321671B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP1015980A 1979-02-02 1980-02-01 Pentofuranosylanthracycline*its manufacture and antitumor containing it Granted JPS55133370A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7903700 1979-02-02

Publications (2)

Publication Number Publication Date
JPS55133370A true JPS55133370A (en) 1980-10-17
JPS6321671B2 JPS6321671B2 (ja) 1988-05-09

Family

ID=10502917

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1015980A Granted JPS55133370A (en) 1979-02-02 1980-02-01 Pentofuranosylanthracycline*its manufacture and antitumor containing it

Country Status (6)

Country Link
US (1) US4254110A (ja)
EP (1) EP0014425B1 (ja)
JP (1) JPS55133370A (ja)
AT (1) ATE1150T1 (ja)
DE (1) DE3060481D1 (ja)
DK (1) DK45080A (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314999A (en) * 1978-07-31 1982-02-09 Proter S.P.A. N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity
ATE15375T1 (de) * 1980-11-01 1985-09-15 Erba Farmitalia Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.
GB2196626B (en) * 1986-10-15 1990-09-19 Erba Farmitalia Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor
FR2660561B1 (fr) * 1990-04-06 1994-05-13 Technomed International Sonde rectale.
US7388083B2 (en) * 2005-03-07 2008-06-17 Solux Corporation Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
US8802830B2 (en) 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130756C (ja) * 1964-03-02
GB1550879A (en) * 1976-12-22 1979-08-22 Farmaceutici Italia Antitumour glycosides
GB1542920A (en) * 1976-12-22 1979-03-28 Farmaceutici Italia Antitumour glycosides
US4181795A (en) * 1978-05-22 1980-01-01 Purdue Research Foundation Daunosamine synthesis

Also Published As

Publication number Publication date
ATE1150T1 (de) 1982-06-15
EP0014425A1 (en) 1980-08-20
EP0014425B1 (en) 1982-06-02
US4254110A (en) 1981-03-03
DK45080A (da) 1980-08-03
JPS6321671B2 (ja) 1988-05-09
DE3060481D1 (en) 1982-07-22

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