ATE15375T1 - Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel. - Google Patents

Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.

Info

Publication number
ATE15375T1
ATE15375T1 AT81109243T AT81109243T ATE15375T1 AT E15375 T1 ATE15375 T1 AT E15375T1 AT 81109243 T AT81109243 T AT 81109243T AT 81109243 T AT81109243 T AT 81109243T AT E15375 T1 ATE15375 T1 AT E15375T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
pharmaceuticals
manufacture
processes
Prior art date
Application number
AT81109243T
Other languages
English (en)
Inventor
Alberto Bargiotti
Giuseppe Cassinelli
Sergio Penco
Federico Arcamone
Anna Maria Casazza
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Application granted granted Critical
Publication of ATE15375T1 publication Critical patent/ATE15375T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT81109243T 1980-11-01 1981-10-29 Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel. ATE15375T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8035195 1980-11-01
EP81109243A EP0051279B1 (de) 1980-11-01 1981-10-29 Anthracyclin-Glycoside, Zwischenprodukte, Verfahren zu beider Herstellung und Arzneimittel

Publications (1)

Publication Number Publication Date
ATE15375T1 true ATE15375T1 (de) 1985-09-15

Family

ID=10517034

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81109243T ATE15375T1 (de) 1980-11-01 1981-10-29 Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.

Country Status (6)

Country Link
US (1) US4393052A (de)
EP (1) EP0051279B1 (de)
JP (1) JPS57106694A (de)
AT (1) ATE15375T1 (de)
CA (1) CA1175420A (de)
DE (2) DE3172152D1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines
JPH01161986U (de) * 1988-04-28 1989-11-10
US4997922A (en) * 1988-09-06 1991-03-05 Sanraku Incorporated Anthracycline derivatives
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
KR0160542B1 (ko) * 1994-12-15 1999-02-01 정선종 모노리틱 마이크로 웨이브 집적회로용 기판 및 그 제조방법
GB0114654D0 (en) * 2001-06-15 2001-08-08 Pharmacia & Upjohn Spa Anti-tumor compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
GB1462387A (en) * 1974-05-02 1977-01-26 Farmaceutici Italia Aminoglycosides
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
GB2034707B (en) * 1978-10-25 1982-09-15 Erba Farmitalia anthracycline glycosides
US4265885A (en) * 1978-10-25 1981-05-05 Farmitalia Carlo Erba S.P.A. Anthracyclines containing branched-chain amino-deoxy sugars
US4254110A (en) * 1979-02-02 1981-03-03 Farmitalia Carlo Erba S.P.A. Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof
DE3060472D1 (en) * 1979-09-01 1982-07-15 Erba Farmitalia Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them

Also Published As

Publication number Publication date
CA1175420A (en) 1984-10-02
US4393052A (en) 1983-07-12
JPS57106694A (en) 1982-07-02
DE3172152D1 (en) 1985-10-10
EP0051279B1 (de) 1985-09-04
EP0051279A1 (de) 1982-05-12
DE51279T1 (de) 1983-05-26
JPS6328079B2 (de) 1988-06-07

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