DE3172152D1 - Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions - Google Patents

Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions

Info

Publication number
DE3172152D1
DE3172152D1 DE8181109243T DE3172152T DE3172152D1 DE 3172152 D1 DE3172152 D1 DE 3172152D1 DE 8181109243 T DE8181109243 T DE 8181109243T DE 3172152 T DE3172152 T DE 3172152T DE 3172152 D1 DE3172152 D1 DE 3172152D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
intermediate compounds
group
hydrogen atom
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181109243T
Other languages
English (en)
Inventor
Alberto Bargiotti
Giuseppe Cassinelli
Sergio Penco
Federico Arcamone
Anna Maria Casazza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3172152D1 publication Critical patent/DE3172152D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE8181109243T 1980-11-01 1981-10-29 Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions Expired DE3172152D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8035195 1980-11-01

Publications (1)

Publication Number Publication Date
DE3172152D1 true DE3172152D1 (en) 1985-10-10

Family

ID=10517034

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8181109243T Expired DE3172152D1 (en) 1980-11-01 1981-10-29 Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions
DE198181109243T Pending DE51279T1 (de) 1980-11-01 1981-10-29 Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198181109243T Pending DE51279T1 (de) 1980-11-01 1981-10-29 Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.

Country Status (6)

Country Link
US (1) US4393052A (de)
EP (1) EP0051279B1 (de)
JP (1) JPS57106694A (de)
AT (1) ATE15375T1 (de)
CA (1) CA1175420A (de)
DE (2) DE3172152D1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines
JPH01161986U (de) * 1988-04-28 1989-11-10
US4997922A (en) * 1988-09-06 1991-03-05 Sanraku Incorporated Anthracycline derivatives
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
KR0160542B1 (ko) * 1994-12-15 1999-02-01 정선종 모노리틱 마이크로 웨이브 집적회로용 기판 및 그 제조방법
GB0114654D0 (en) * 2001-06-15 2001-08-08 Pharmacia & Upjohn Spa Anti-tumor compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
GB1462387A (en) * 1974-05-02 1977-01-26 Farmaceutici Italia Aminoglycosides
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
GB2034707B (en) * 1978-10-25 1982-09-15 Erba Farmitalia anthracycline glycosides
US4265885A (en) * 1978-10-25 1981-05-05 Farmitalia Carlo Erba S.P.A. Anthracyclines containing branched-chain amino-deoxy sugars
US4254110A (en) * 1979-02-02 1981-03-03 Farmitalia Carlo Erba S.P.A. Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof
DE3060472D1 (en) * 1979-09-01 1982-07-15 Erba Farmitalia Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them

Also Published As

Publication number Publication date
CA1175420A (en) 1984-10-02
ATE15375T1 (de) 1985-09-15
US4393052A (en) 1983-07-12
JPS57106694A (en) 1982-07-02
EP0051279B1 (de) 1985-09-04
EP0051279A1 (de) 1982-05-12
DE51279T1 (de) 1983-05-26
JPS6328079B2 (de) 1988-06-07

Similar Documents

Publication Publication Date Title
MY101359A (en) 7-acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, their starting compounds and their preparation
LU91362I2 (fr) Palipéridone et ses dérivés pharmaceutiquement acceptables (INVEGA)
PT92035A (pt) Processo para a preparacao de derivados de piridina
DE3164763D1 (en) Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions
DE3172152D1 (en) Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions
UA27108A1 (uk) Аhтрацикліhові глікозиди та їх фармацевтичhо прийhятhі кислотhо-адитивhі солі, спосіб їх одержаhhя, похідhі 1,6-дийод-3-оксапеhтаhу та спосіб їх одержаhhя
ES8403910A1 (es) Procedimiento para la preparacion de nitratos de amino-deso-xi-1.4;3.6-dianhidro-hexito,asi como de sus sales de adicionacida farmacologicamente inocuas
NO146025C (no) Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzapinderivater
IL70560A0 (en) Dialkylaminoalkoxybenzyl alcohol derivatives,their preparation and pharmaceutical compositions containing them
ES554635A0 (es) Un procedimiento para preparar derivados de vinilisoquinolina
DK45080A (da) Fremgangsmaade til fremstilling af anthracyclinglycosider
DE3064485D1 (en) Anthracycline glycosides, process for their preparation and therapeutical composition containing them
AU639154B2 (en) New imidazole compounds, a process for the preparation thereof, and pharmaceutical compositions containing them
MY103368A (en) 1,3-dioxanes
AU587086B2 (en) New pyridine compounds with basic substituents, a process for their preparation, medicaments containing them, and their use
ES8200689A1 (es) Un procedimiento para la produccion de analogos de cefalosporina.
ES8201993A1 (es) Un procedimiento para la preparacion de tiazoles
ATE34740T1 (de) (bis(hydroxymethyl)methyl)-isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ATE36154T1 (de) 4-phenylaminopyridin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ES8304532A1 (es) "procedimiento de preparacion de derivados de etanolamina".
MY103601A (en) New 6-aminomethyl-furo-(3,4-c)-pyridine derivatives their preparation and therapeutic compositions containing the same
ES8203328A1 (es) Un procedimiento para la preparacion de 6-fluordihidroxifenilalaninas.
HUT39731A (en) Process for preparing arphamenine derivatives and pharmaceutical compositions containing such compounds
MX4658E (es) Procedimiento para preparar compuestos de acidos 3-cefem-4-carboxilicos 3,7 disubstituidos

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee