JPS55122768A - Hydroxypyrimidine derivative*its manufacture and use - Google Patents

Hydroxypyrimidine derivative*its manufacture and use

Info

Publication number
JPS55122768A
JPS55122768A JP2931280A JP2931280A JPS55122768A JP S55122768 A JPS55122768 A JP S55122768A JP 2931280 A JP2931280 A JP 2931280A JP 2931280 A JP2931280 A JP 2931280A JP S55122768 A JPS55122768 A JP S55122768A
Authority
JP
Japan
Prior art keywords
manufacture
hydroxypyrimidine derivative
hydroxypyrimidine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2931280A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6126996B2 (da
Inventor
Usanu Andore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PURODEYUI SHIMIIKU SOC ET
Original Assignee
PURODEYUI SHIMIIKU SOC ET
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26270867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS55122768(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PURODEYUI SHIMIIKU SOC ET filed Critical PURODEYUI SHIMIIKU SOC ET
Publication of JPS55122768A publication Critical patent/JPS55122768A/ja
Publication of JPS6126996B2 publication Critical patent/JPS6126996B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2931280A 1979-03-10 1980-03-10 Hydroxypyrimidine derivative*its manufacture and use Granted JPS55122768A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7908494 1979-03-10
GB7914987 1979-04-30

Publications (2)

Publication Number Publication Date
JPS55122768A true JPS55122768A (en) 1980-09-20
JPS6126996B2 JPS6126996B2 (da) 1986-06-23

Family

ID=26270867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2931280A Granted JPS55122768A (en) 1979-03-10 1980-03-10 Hydroxypyrimidine derivative*its manufacture and use

Country Status (24)

Country Link
JP (1) JPS55122768A (da)
AR (1) AR222691A1 (da)
AU (1) AU533547B2 (da)
BE (1) BE881752A (da)
CA (1) CA1132561A (da)
CH (1) CH644368A5 (da)
DE (3) DE3050999C2 (da)
EG (1) EG14282A (da)
FI (1) FI66357C (da)
FR (2) FR2451370A1 (da)
GB (1) GB2045756B (da)
HK (1) HK55383A (da)
IE (1) IE49547B1 (da)
IN (1) IN153791B (da)
LU (1) LU82185A1 (da)
MX (1) MX6218E (da)
MY (1) MY8400200A (da)
NL (1) NL184833C (da)
NO (1) NO154054C (da)
NZ (1) NZ192927A (da)
OA (1) OA06484A (da)
PT (1) PT70882A (da)
SE (1) SE435180B (da)
SG (1) SG22683G (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147876A (en) * 1988-12-29 1992-09-15 Mitsui Petrochemical Industries, Ltd. 2,6-di,2,4,6-, 2,5,6-tri and 2,4,5,6-tetra-substituted pyrimidines, their pharmaceutically acceptable salts, pharmaceutical compositions containing same and their use in the treatment of neurological diseases
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE894517A (fr) * 1981-10-16 1983-01-17 Sod Conseils Rech Applic Nouveau derive de l'isopropylamino pyrimidine, sa preparation et composition therapeutiques a base de ses composes
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4673677A (en) * 1983-10-03 1987-06-16 Pfizer Inc. Method for treatment of gastrointestinal disorders
US4711888A (en) 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines
WO1989000423A1 (en) * 1987-07-09 1989-01-26 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US4910204A (en) * 1988-06-28 1990-03-20 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US4940712A (en) * 1989-05-26 1990-07-10 Pfizer Inc. Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US9133212B1 (en) * 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB741667A (en) * 1952-12-05 1955-12-07 Ici Ltd New pyrimidine derivatives
GB756189A (en) * 1954-02-01 1956-08-29 Ici Ltd New pyrimidine derivatives
ZA711152B (en) * 1970-03-02 1971-11-24 Ici Ltd Manufacture of pyrimidines
GB1525995A (en) * 1976-02-18 1978-09-27 Soc D Etudes Prod Chimique Aminopyrimidine salt

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147876A (en) * 1988-12-29 1992-09-15 Mitsui Petrochemical Industries, Ltd. 2,6-di,2,4,6-, 2,5,6-tri and 2,4,5,6-tetra-substituted pyrimidines, their pharmaceutically acceptable salts, pharmaceutical compositions containing same and their use in the treatment of neurological diseases
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines

Also Published As

Publication number Publication date
NZ192927A (en) 1981-07-13
FR2451370B1 (da) 1983-05-13
NL8001289A (nl) 1980-09-12
FI66357C (fi) 1984-10-10
AU533547B2 (en) 1983-12-01
MX6218E (es) 1984-12-21
NO800664L (no) 1980-09-11
DE3016752C2 (da) 1987-06-25
EG14282A (en) 1983-09-30
NO154054B (no) 1986-04-01
IE49547B1 (en) 1985-10-30
CH644368A5 (en) 1984-07-31
AU5624880A (en) 1980-09-18
DE3009071C2 (de) 1985-11-14
NL184833B (nl) 1989-06-16
CA1132561A (en) 1982-09-28
GB2045756A (en) 1980-11-05
NL184468B (nl) 1989-03-01
NL184833C (nl) 1989-11-16
HK55383A (en) 1983-11-25
NO154054C (no) 1986-07-09
LU82185A1 (fr) 1980-06-06
AR222691A1 (es) 1981-06-15
OA06484A (fr) 1981-07-31
GB2045756B (en) 1983-01-26
DE3016752A1 (de) 1980-12-04
IN153791B (da) 1984-08-18
FR2451191A1 (fr) 1980-10-10
FI66357B (fi) 1984-06-29
DE3050999A1 (da) 1985-08-14
SE8001812L (sv) 1980-09-11
MY8400200A (en) 1984-12-31
FR2451191B1 (da) 1983-04-29
BE881752A (fr) 1980-05-30
IE800477L (en) 1980-09-10
SE435180B (sv) 1984-09-10
FR2451370A1 (fr) 1980-10-10
JPS6126996B2 (da) 1986-06-23
FI800566A (fi) 1980-09-11
SG22683G (en) 1983-12-16
PT70882A (en) 1980-03-01
DE3050999C2 (de) 1986-08-14
DE3009071A1 (de) 1980-09-11

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