JPS5495519A - Novel acylanilide*its manufacture and drug composition having anti male sex hormone action containing said anilide - Google Patents

Novel acylanilide*its manufacture and drug composition having anti male sex hormone action containing said anilide

Info

Publication number
JPS5495519A
JPS5495519A JP15429978A JP15429978A JPS5495519A JP S5495519 A JPS5495519 A JP S5495519A JP 15429978 A JP15429978 A JP 15429978A JP 15429978 A JP15429978 A JP 15429978A JP S5495519 A JPS5495519 A JP S5495519A
Authority
JP
Japan
Prior art keywords
acylanilide
anilide
novel
manufacture
drug composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15429978A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0223537B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Alasdair Thomas Glen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of JPS5495519A publication Critical patent/JPS5495519A/ja
Publication of JPH0223537B2 publication Critical patent/JPH0223537B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/115Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/305Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • C07C59/315Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups containing halogen
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03BAPPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B31/00Associated working of cameras or projectors with sound-recording or sound-reproducing means
    • G03B31/02Associated working of cameras or projectors with sound-recording or sound-reproducing means in which sound track is on a moving-picture film

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP15429978A 1977-12-15 1978-12-15 Novel acylanilide*its manufacture and drug composition having anti male sex hormone action containing said anilide Granted JPS5495519A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5222377 1977-12-15

Publications (2)

Publication Number Publication Date
JPS5495519A true JPS5495519A (en) 1979-07-28
JPH0223537B2 JPH0223537B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-05-24

Family

ID=10463104

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15429978A Granted JPS5495519A (en) 1977-12-15 1978-12-15 Novel acylanilide*its manufacture and drug composition having anti male sex hormone action containing said anilide

Country Status (21)

Country Link
US (1) US4191775A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0002892B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5495519A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT360974B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU522716B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG31225A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1123008A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS208112B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD139844A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2862459D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK556978A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES476049A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI70007C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU176981B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE49866B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL56155A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1107675B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO149035C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ189086A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT68922A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA786781B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ197008A (en) * 1980-05-22 1984-10-19 Ici Ltd Acylanilide derivatives and pharmaceutical compositions
AU8961382A (en) * 1981-11-06 1983-05-12 Imperial Chemical Industries Plc Amide derivatives
GB8504093D0 (en) * 1985-02-18 1985-03-20 Ici Plc Alkene alkyne/cycloalkylene derivatives
US5236953A (en) * 1982-04-14 1993-08-17 Imperial Chemical Industries Plc Alkene, alkyne or cycloalkylene derivatives
LU88769I2 (fr) * 1982-07-23 1996-11-05 Zeneca Ltd Bicalutamide et ses sels et esters pharmaceutiquement acceptables (Casodex (R))
US4885289A (en) * 1983-12-12 1989-12-05 Breuer Miklos M Alteration of character of male beard growth
GB8406000D0 (en) * 1984-03-07 1984-04-11 Ici Plc Olefine derivatives
GB8617652D0 (en) * 1986-07-18 1986-08-28 Ici Plc Acylanilide derivatives
CA1327600C (en) * 1987-05-22 1994-03-08 Ernest Felder Process for the preparation of 5-acylamino-2,4,6- triiodo-or tribromo-benzoic acid derivatives and corresponding novel 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives obtained by said process
GB9214120D0 (en) * 1991-07-25 1992-08-12 Ici Plc Therapeutic amides
JPH07504646A (ja) * 1991-11-05 1995-05-25 ザ、ジレット、カンパニー 毛成長の速度及び特徴の変化
US5364885A (en) * 1992-11-13 1994-11-15 Ahluwalia Gurpreet S Reduction of hair growth
US6743419B1 (en) 1992-12-22 2004-06-01 The Gillette Company Method of reducing hair growth employing sulfhydryl active compounds
US5411991A (en) * 1992-12-22 1995-05-02 Shander; Douglas Method of reducing hair growth employing sulfhydryl active compounds
GB9305295D0 (en) * 1993-03-15 1993-05-05 Zeneca Ltd Therapeutic compounds
GB9310095D0 (en) * 1993-05-17 1993-06-30 Zeneca Ltd Therapeutic compounds
US5648394A (en) * 1993-05-27 1997-07-15 Boxall; Brian Alfred Topical composition for inhibiting hair growth
US6414017B2 (en) 1993-05-28 2002-07-02 The Gillette Company Inhibition of hair growth
US6248751B1 (en) 1993-05-28 2001-06-19 Gurpreet S. Ahluwalia Inhibition of hair growth
JPH0759644A (ja) * 1993-08-24 1995-03-07 Nobuyuki Yamamoto 納骨用仏像
US5474763A (en) * 1994-03-11 1995-12-12 Shander; Douglas Reduction of hair growth
US5455234A (en) * 1994-03-16 1995-10-03 Ahluwalia; Gurpreet S. Inhibition of hair growth
US5468476A (en) * 1994-03-16 1995-11-21 Ahluwalia; Gurpreet S. Reduction of hair growth
DE69529665T2 (de) * 1994-06-27 2004-02-19 Neutron Therapies Inc., San Diego Bor enthaltende hormonanaloga und verfahren fuer ihre verwendung zur bildlichen darstellung oder zum abtoeten von zellen, die hormonrezeptoren besitzen
US5554608A (en) * 1994-09-28 1996-09-10 Ahluwalia; Gurpreet S. Inhibition of hair growth
US5674477A (en) * 1995-02-28 1997-10-07 Ahluwalia; Gurpreet S. Reduction of hair growth
ES2175084T3 (es) * 1995-02-28 2002-11-16 Gillette Co Uso de supresores de angiogenesis para inhibir el crecimiento del pelo.
US5728736A (en) * 1995-11-29 1998-03-17 Shander; Douglas Reduction of hair growth
US5652273A (en) 1995-11-30 1997-07-29 Henry; James Reduction of hair growth
ATE211903T1 (de) * 1996-03-06 2002-02-15 Oreal Verwendung von n-aryl-2-hydroxyalkylamiden zur induzierung und/oder stimulation des haarwachstums und/oder zur verlangsamung des haarausfalls
FR2747039B1 (fr) * 1996-04-05 1998-05-22 Oreal Utilisation du n-(3,4-dicyano-phenyl)- 3,3,3-trifluoro- 2-hydroxy-2-methylpropionamide pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
FR2745717B1 (fr) * 1996-03-06 1998-04-17 Oreal Utilisation de n-aryl-2-hydroxyalkylamides pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US5908867A (en) * 1996-07-18 1999-06-01 Henry; James P. Reduction of hair growth
US5840752A (en) * 1996-11-21 1998-11-24 Henry; James P. Reduction of hair growth
US7759520B2 (en) * 1996-11-27 2010-07-20 University Of Tennessee Research Foundation Synthesis of selective androgen receptor modulators
US7518013B2 (en) * 2000-08-24 2009-04-14 University Of Tennessee Research Foundation Selective androgen receptor modulators
US6995284B2 (en) * 2000-08-24 2006-02-07 The University Of Tennessee Research Foundation Synthesis of selective androgen receptor modulators
US6071957A (en) * 1996-11-27 2000-06-06 The University Of Tennessee Research Corporation Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer
US20050038110A1 (en) * 2000-08-24 2005-02-17 Steiner Mitchell S. Selective androgen receptor modulators and methods of use thereof
ZA9711121B (en) * 1996-12-13 1998-06-23 Handelman Joseph H Reduction of hair growth.
US6037326A (en) * 1996-12-31 2000-03-14 Styczynski; Peter Reduction of hair growth
US6160011A (en) * 1997-05-30 2000-12-12 The University Of Tennessee Research Corporation Non-steroidal agonist compounds and their use in male hormone therapy
US6245804B1 (en) 1997-05-30 2001-06-12 Schering Aktiengesellschaft Nonsteroidal gestagens
DE19723722A1 (de) * 1997-05-30 1998-12-10 Schering Ag Nichtsteroidale Gestagene
WO1998055153A1 (en) * 1997-06-04 1998-12-10 The University Of Tennessee Research Corporation Non-steroidal radiolabeled agonist/antagonist compounds and their use in prostate cancer imaging
US5939458A (en) * 1997-09-22 1999-08-17 Henry; James P. Reduction of hair growth
US5958946A (en) * 1998-01-20 1999-09-28 Styczynski; Peter Modulation of hair growth
US6060471A (en) * 1998-01-21 2000-05-09 Styczynski; Peter Reduction of hair growth
GB9804648D0 (en) 1998-03-06 1998-04-29 Zeneca Ltd Chemical compounds
GB9805520D0 (en) 1998-03-17 1998-05-13 Zeneca Ltd Chemical compounds
US20040176470A1 (en) * 1998-05-07 2004-09-09 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
GB9811427D0 (en) 1998-05-29 1998-07-22 Zeneca Ltd Chemical compounds
US6020006A (en) * 1998-10-27 2000-02-01 The Gillette Company Reduction of hair growth
US6184249B1 (en) * 1998-12-18 2001-02-06 Biophysica, Inc. Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
US6121269A (en) * 1999-02-22 2000-09-19 Henry; James P. Reduction of hair growth
ATE399753T1 (de) 1999-09-04 2008-07-15 Astrazeneca Ab Amide als pyruvatdehydrogenaseinhibitoren
DE60031699T2 (de) 1999-09-04 2007-08-30 Astrazeneca Ab Hydroxyacetamidobenzolsulfonamidderivate
DE60009319T2 (de) 1999-09-04 2005-03-31 Astrazeneca Ab Substituierte n-phenyl-2-hydroxy-2-methyl-3,3,3-trifluorpropanamid-derivative zur erhöhung der pyruvatdehydrogenaseaktivität
US6235737B1 (en) * 2000-01-25 2001-05-22 Peter Styczynski Reduction of hair growth
US6299865B1 (en) 2000-05-02 2001-10-09 Peter Styczynski Reduction of hair growth
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7001911B2 (en) 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
CA2413417A1 (en) 2000-06-28 2002-01-03 Bristol-Myers Squibb Company Selective androgen receptor modulators and methods for their identification, design and use
EP1310488A4 (en) * 2000-08-09 2005-08-10 Mitsubishi Pharma Corp CONDENSED BICYCLIC AMIDE COMPOUNDS AND MEDICAL USES THEREOF
US7855229B2 (en) * 2000-08-24 2010-12-21 University Of Tennessee Research Foundation Treating wasting disorders with selective androgen receptor modulators
US6998500B2 (en) * 2000-08-24 2006-02-14 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US7645898B2 (en) * 2000-08-24 2010-01-12 University Of Tennessee Research Foundation Selective androgen receptor modulators and method of use thereof
DK1401801T3 (da) 2000-08-24 2007-03-05 Univ Tennessee Res Foundation Selektive androgenreceptormodulatorer og fremgangsmåder til anvendelse deraf
US7622503B2 (en) * 2000-08-24 2009-11-24 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
IL154425A0 (en) 2000-08-24 2003-09-17 Univ Tennessee Res H Corp Selective androgen receptor modulators and methods of use thereof
US7026500B2 (en) * 2000-08-24 2006-04-11 University Of Tennessee Research Foundation Halogenated selective androgen receptor modulators and methods of use thereof
US7919647B2 (en) * 2000-08-24 2011-04-05 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US20040260108A1 (en) * 2001-06-25 2004-12-23 Dalton James T. Metabolites of selective androgen receptor modulators and methods of use thereof
US8445534B2 (en) * 2000-08-24 2013-05-21 University Of Tennessee Research Foundation Treating androgen decline in aging male (ADAM)-associated conditions with SARMs
US6838484B2 (en) * 2000-08-24 2005-01-04 University Of Tennessee Research Foundation Formulations comprising selective androgen receptor modulators
US8008348B2 (en) * 2001-12-06 2011-08-30 University Of Tennessee Research Foundation Treating muscle wasting with selective androgen receptor modulators
US20070173546A1 (en) * 2000-08-24 2007-07-26 Dalton James T Selective androgen receptor modulators and method of use thereof
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DE10051981A1 (de) 2000-10-20 2002-05-02 Bayer Ag Substituierte Phenyluracile
WO2002062341A1 (en) * 2001-02-07 2002-08-15 University Of Florida Method and composition for the control of hair growth
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20060287282A1 (en) * 2001-06-25 2006-12-21 Steiner Mitchell S Compositions comprising a SARM ad GnRH agonist or a GnRH antagonist, and methods of use thereof
US7439271B2 (en) 2001-06-27 2008-10-21 The Gillette Company Reduction of hair growth
US20030036561A1 (en) * 2001-08-10 2003-02-20 Peter Styczynski Reduction of hair growth
US6743822B2 (en) 2001-08-10 2004-06-01 The Gillette Company Reduction of hair growth
US7261878B2 (en) * 2001-08-10 2007-08-28 The Gillette Company Reduction of hair growth
US20070161608A1 (en) * 2001-12-06 2007-07-12 Dalton James T Selective androgen receptor modulators for treating muscle wasting
MXPA04005519A (es) * 2001-12-06 2005-06-20 Gtx Inc Tratamiento del desgaste muscular con moduladores receptores de androgeno selectivos.
US8853266B2 (en) * 2001-12-06 2014-10-07 University Of Tennessee Research Foundation Selective androgen receptor modulators for treating diabetes
ES2331178T3 (es) 2001-12-13 2009-12-23 Sumitomo Chemical Company, Limited Cristales de bicalutamida y metodo para su produccion.
AU2002364082A1 (en) * 2001-12-19 2003-07-09 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function
US7160921B2 (en) * 2002-01-29 2007-01-09 The Gillette Company Reduction of hair growth
US20040198821A1 (en) * 2002-01-29 2004-10-07 Hwang Cheng Shine Reduction of hair growth
CN101732298B (zh) * 2002-02-07 2012-09-19 田纳西大学研究基金会 用sarms治疗良性前列腺增生
EP1487780A4 (en) * 2002-02-28 2005-11-16 Univ Tennessee Res Foundation HALOACETAMIDE AND AZID SUBSTITUTED COMPOUNDS AND METHODS OF USE THEREOF
US7772433B2 (en) * 2002-02-28 2010-08-10 University Of Tennessee Research Foundation SARMS and method of use thereof
US7803970B2 (en) * 2002-02-28 2010-09-28 University Of Tennessee Research Foundation Multi-substitued selective androgen receptor modulators and methods of use thereof
AU2003217304A1 (en) * 2002-02-28 2003-09-16 The University Of Tennessee Research Corporation Radiolabeled selective androgen receptor modulators and their use in prostate cancer imaging and therapy
KR20040101251A (ko) * 2002-02-28 2004-12-02 유니버시티 오브 테네시 리서치 파운데이션 다치환된 선택적 안드로겐 수용체 모듈레이터 및 이를사용하는 방법
US20030199584A1 (en) * 2002-04-11 2003-10-23 Ahluwalia Gurpreet S. Reduction of hair growth
US7741371B2 (en) * 2002-06-17 2010-06-22 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
AU2003241583B2 (en) * 2002-06-17 2009-05-21 University Of Tennessee Research Foundation N-bridged selective androgen receptor modulators and methods of use thereof
JP2006505563A (ja) * 2002-10-15 2006-02-16 ジーティーエックス・インコーポレイテッド 選択的アンドロゲン受容体調節剤による肥満治療
AU2003287077B2 (en) * 2002-10-15 2007-09-20 University Of Tennessee Research Foundation Methylene-bridged selective androgen receptor modulators and methods of use thereof
US20040197928A1 (en) * 2002-10-15 2004-10-07 Dalton James T. Method for detecting selective androgen receptor modulators
JP2006505564A (ja) * 2002-10-16 2006-02-16 ジーティーエックス・インコーポレイテッド Sarmによる高齢男性のアンドロゲン減少に関連する病気の治療
US20060276539A1 (en) * 2002-10-16 2006-12-07 Dalton James T Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS
US20040087810A1 (en) * 2002-10-23 2004-05-06 Dalton James T. Irreversible selective androgen receptor modulators and methods of use thereof
US8309603B2 (en) * 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
US20040141935A1 (en) * 2003-01-21 2004-07-22 Peter Styczynski Reduction of hair growth
US20040167103A1 (en) * 2003-02-24 2004-08-26 Dalton James T. Haloacetamide and azide substituted compounds and methods of use thereof
US7015349B2 (en) * 2003-03-26 2006-03-21 The Gillette Company Reduction of hair growth
US20050112075A1 (en) * 2003-11-25 2005-05-26 Hwang Cheng S. Reduction of hair growth
MXPA06000119A (es) * 2003-12-16 2006-03-21 Gtx Inc Profarmacos de moduladores receptores de androgenos selectivos y metodos de uso de los mismos.
US20050249685A1 (en) * 2004-04-27 2005-11-10 Natalia Botchkareva Reduction of hair growth
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US20110237664A1 (en) * 2004-06-07 2011-09-29 Dalton James T Selective androgen receptor modulators for treating diabetes
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
US20060258628A1 (en) * 2004-07-20 2006-11-16 Steiner Mitchell S Compositions comprising 5-alpha reductase inhibitors, and SARMs and methods of use thereof
BRPI0519217A2 (pt) * 2004-12-22 2009-01-06 Gillette Co reduÇço do crescimento de pÊlos com inibidores de survivina
EP1827280A2 (en) * 2004-12-22 2007-09-05 The Gillette Company Reduction of hair growth
US7618956B2 (en) * 2005-05-31 2009-11-17 The Gillette Company Reduction of hair growth
US7709516B2 (en) 2005-06-17 2010-05-04 Endorecherche, Inc. Helix 12 directed non-steroidal antiandrogens
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
CN103251579B (zh) 2006-08-24 2016-12-28 田纳西大学研究基金会 取代的n-酰基苯胺及其使用方法
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US9284345B2 (en) 2007-04-12 2016-03-15 Endorecherche, Inc. 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
EP2834216A1 (en) 2012-04-04 2015-02-11 Catylix Inc. Selective androgen receptor modulators
US10314807B2 (en) 2012-07-13 2019-06-11 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9969683B2 (en) 2012-07-13 2018-05-15 Gtx, Inc. Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10987334B2 (en) 2012-07-13 2021-04-27 University Of Tennessee Research Foundation Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
WO2014011220A2 (en) 2012-07-13 2014-01-16 Gtx, Inc. A method of treating androgen receptor (ar)-positive breast cancers with selective androgen receptor modulator (sarms)
US9682960B2 (en) 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4981332A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-11-24 1974-08-06
US3995060A (en) * 1972-06-20 1976-11-30 Schering Corporation Antiandrogenic agents and method for the treatment of androgen dependent disease states
JPS52128329A (en) * 1976-04-15 1977-10-27 Teikoku Hormone Mfg Co Ltd Anilide derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793110A1 (de) * 1968-08-02 1971-12-16 Basf Ag Substituierte Saeureanilide
DE2042300A1 (de) * 1970-08-26 1972-03-23 Farbwerke Hoechst AG, vormals Meister Lucius & Brüning, 6000 Frankfurt Halogencarbonsäureanilide, ihre Herstellung und Verwendung als Herbizide
CA1012462A (en) * 1971-06-18 1977-06-21 Scherico Ltd. Pharmaceutical composition containing substituted anilides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995060A (en) * 1972-06-20 1976-11-30 Schering Corporation Antiandrogenic agents and method for the treatment of androgen dependent disease states
JPS4981332A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-11-24 1974-08-06
JPS52128329A (en) * 1976-04-15 1977-10-27 Teikoku Hormone Mfg Co Ltd Anilide derivative

Also Published As

Publication number Publication date
HU176981B (hu) 1981-06-28
NO784211L (no) 1979-06-18
ATA874278A (de) 1980-07-15
FI70007C (fi) 1986-09-12
BG31225A3 (bg) 1981-11-16
DE2862459D1 (en) 1985-03-21
IE49866B1 (en) 1986-01-08
AU4220078A (en) 1979-06-21
CS208112B2 (en) 1981-08-31
AT360974B (de) 1981-02-10
NO149035B (no) 1983-10-24
AU522716B2 (en) 1982-06-24
NO149035C (no) 1984-02-01
IT7852280A0 (it) 1978-12-13
EP0002892B1 (en) 1985-02-06
IT1107675B (it) 1985-11-25
DD139844A5 (de) 1980-01-23
JPH0223537B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-05-24
PT68922A (en) 1979-01-01
DK556978A (da) 1979-06-16
FI783820A7 (fi) 1979-06-16
US4191775A (en) 1980-03-04
IL56155A (en) 1982-09-30
ZA786781B (en) 1979-11-28
ES476049A1 (es) 1979-05-16
IL56155A0 (en) 1979-03-12
NZ189086A (en) 1980-09-12
CA1123008A (en) 1982-05-04
EP0002892A1 (en) 1979-07-11
FI70007B (fi) 1986-01-31

Similar Documents

Publication Publication Date Title
JPS5495519A (en) Novel acylanilide*its manufacture and drug composition having anti male sex hormone action containing said anilide
JPS545021A (en) Release sustaining medical composition * production and use thereof
JPS5634628A (en) Veterinary medicine composition and its manufacture
JPS54106424A (en) N substituted omegaaaminoalkanoyllomegaa aminoalkanoic acid* its use and manufacture and drug containing it
JPS5492938A (en) Peptide compound*its manufacture and medicine
JPS5489031A (en) Stabilized sterilizing agent composition and production thereof
JPS55100313A (en) Drug composition and its manufacture
JPS5592383A (en) Novel substituted 55*22imidazolinee22yl** aminopyrimidine*its manufacture and its use as drug
JPS5444685A (en) 22formyl quinoxalinee1*44dioxideecyanoacetyl hydrazone*its manufacture and medicine containing it
JPS5555200A (en) Steroid compound and medicine composition
JPS5466675A (en) Omegaamercaptopropionamido*its manufacture and medical composition
JPS54112859A (en) Guanidine derivative*its manufacture and drug composition containing it
JPS5517382A (en) Nnarylsulfonylpyrrole*its manufacture and medicine containing it
JPS53145905A (en) Pharmaceutical composition and production thereof
JPS5362834A (en) Pharmaceutical composition and use thereof
JPS5522692A (en) Stable liquid drug composition and its manufacture
JPS5448776A (en) 2*44diaminopyrimidine derivative*its manufacture and medicine as active component
JPS5524199A (en) Substituted anthranilic acid amide*its manufacture and drug composition containing it
JPS5476543A (en) Pentapeptide composition*its manufacture and use
JPS5359655A (en) Production of novel corticoid and pharmaceutical composition containin the same with effective antiiinflammatory action
JPS5320433A (en) Pharmaceutical composition and application
PH12590A (en) 4a-aryl octahydro-1h-2-pyrindines and pharmaceutical composition thereof
JPS5490167A (en) Novel tetracyclononane derivative*its manufacture and antivirulent medical composition containing it
PH14049A (en) 9-aminodeoxyclavulanic acid compound and pharmaceutical composition
JPS5498720A (en) Acylhydro carbylamine alkanic acid*its manufacture*application and medicine containing it