JPS51125382A - Production of nucleotide - Google Patents

Production of nucleotide

Info

Publication number
JPS51125382A
JPS51125382A JP51019810A JP1981076A JPS51125382A JP S51125382 A JPS51125382 A JP S51125382A JP 51019810 A JP51019810 A JP 51019810A JP 1981076 A JP1981076 A JP 1981076A JP S51125382 A JPS51125382 A JP S51125382A
Authority
JP
Japan
Prior art keywords
nucleotide
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51019810A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6139318B2 (https=
Inventor
Fuooruburiyutsugen Herumuuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS51125382A publication Critical patent/JPS51125382A/ja
Publication of JPS6139318B2 publication Critical patent/JPS6139318B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
JP51019810A 1975-02-24 1976-02-24 Production of nucleotide Granted JPS51125382A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752508312 DE2508312A1 (de) 1975-02-24 1975-02-24 Neues verfahren zur herstellung von nucleosiden

Publications (2)

Publication Number Publication Date
JPS51125382A true JPS51125382A (en) 1976-11-01
JPS6139318B2 JPS6139318B2 (https=) 1986-09-03

Family

ID=5939872

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51019810A Granted JPS51125382A (en) 1975-02-24 1976-02-24 Production of nucleotide

Country Status (12)

Country Link
US (1) US4082911A (https=)
JP (1) JPS51125382A (https=)
BE (1) BE838879A (https=)
CA (1) CA1065315A (https=)
CH (1) CH626093A5 (https=)
DE (1) DE2508312A1 (https=)
DK (1) DK138900C (https=)
FR (1) FR2301536A1 (https=)
GB (1) GB1542442A (https=)
LU (1) LU74411A1 (https=)
NL (1) NL7601625A (https=)
SE (1) SE7602109L (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53108986A (en) * 1977-03-02 1978-09-22 Mitsui Toatsu Chem Inc Preparation of nucleosides and nucleotides

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721466A1 (de) * 1977-05-12 1978-11-16 Robugen Gmbh Verfahren zur herstellung von 2'-desoxyribofuranosylnucleosiden
US4195176A (en) * 1977-10-11 1980-03-25 Warner-Lambert Company Imidazole compounds, methods for their production and conversion of said compounds into (R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazol[4,5-d][1,3]diazepin-8-ol
DE2757365A1 (de) * 1977-12-20 1979-06-21 Schering Ag Neues verfahren zur herstellung von nucleosiden
JPH029511U (https=) * 1988-06-21 1990-01-22
ZA923640B (en) * 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
CA2091732C (en) * 1992-07-08 1998-07-21 Anica Markovac A process for the preparation of 2-fluoro-9-(2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl) adenine
JPH07276137A (ja) * 1994-03-31 1995-10-24 Osaka Diamond Ind Co Ltd 切削・研削用工具
DE19513330A1 (de) * 1995-04-03 1996-10-10 Schering Ag Neues Verfahren zur Herstellung von Nucleosiden
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
EP1736478B1 (en) 2000-05-26 2015-07-22 IDENIX Pharmaceuticals, Inc. Methods and compositions for treating flaviviruses and pestiviruses
NZ537662A (en) 2002-06-28 2007-10-26 Idenix Cayman Ltd 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
CN1678326A (zh) 2002-06-28 2005-10-05 埃迪尼克斯(开曼)有限公司 用于治疗黄病毒感染的2'－c－甲基－3'－o－l－缬氨酸酯核糖呋喃基胞苷
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
LT1576138T (lt) 2002-11-15 2017-06-26 Idenix Pharmaceuticals Llc 2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija
AU2003300901A1 (en) 2002-12-12 2004-06-30 Idenix (Cayman) Limited Process for the production of 2'-branched nucleosides
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US7038038B2 (en) * 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US6943249B2 (en) * 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
KR20060015542A (ko) 2003-04-28 2006-02-17 이데닉스 (케이만) 리미티드 산업 규모의 뉴클레오시드 합성
WO2005003374A2 (en) 2003-06-30 2005-01-13 Idenix (Cayman) Limited SYNTHESIS OF β-L-2-DEOXY NUCLEOSIDES
AT502635A1 (de) * 2005-11-09 2007-05-15 Saischek Und Partner Meg Neue 1,3-dithioverbindungen, verfahren zu deren herstellung und ihre verwendung
ES2422290T3 (es) 2005-12-23 2013-09-10 Idenix Pharmaceuticals Inc Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados
EP2050757A1 (en) * 2007-10-10 2009-04-22 Cilag AG Method of producing 2' -deoxy-5-azacytidine (Decitabine)
EP2048151A1 (en) * 2007-10-10 2009-04-15 Cilag AG Method for producing nucleosides by direct glycosylation of the nucleoside base
PL3692983T3 (pl) * 2008-05-15 2021-12-27 Celgene Corporation Doustne formulacje analogów cytydyny i sposoby ich zastosowania
WO2010014883A2 (en) 2008-08-01 2010-02-04 Dr. Reddy's Laboratories Ltd. Azacitidine process and polymorphs
EP2520581A1 (en) * 2008-08-06 2012-11-07 Sicor, Inc. Method for the determination the purity of 5-Azacytidine
JP5650643B2 (ja) * 2008-08-08 2015-01-07 サイノファーム タイワン リミテッド ５−アザシトシンヌクレオシド及びその誘導体の製造方法
EP2424845A4 (en) * 2009-04-27 2014-03-05 Reddys Lab Ltd Dr PREPARATION OF DECITABIN
CN103619864A (zh) 2011-03-31 2014-03-05 细胞基因国际有限公司 5-氮杂胞苷的合成
CN108239128B (zh) * 2016-12-23 2019-03-29 江苏奥赛康药业股份有限公司 β-核苷类化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
US3352849A (en) * 1965-10-24 1967-11-14 Merck & Co Inc 6-aza-2'-deoxyuridines
SU452961A3 (ru) * 1969-04-11 1974-12-05 Шеринг Аг. (Фирма) Способ получени пиримидиннуклеозидов
DE2122991C2 (de) * 1971-05-04 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53108986A (en) * 1977-03-02 1978-09-22 Mitsui Toatsu Chem Inc Preparation of nucleosides and nucleotides

Also Published As

Publication number Publication date
DK138900B (da) 1978-11-13
GB1542442A (en) 1979-03-21
DK77176A (da) 1976-08-25
CA1065315A (en) 1979-10-30
US4082911A (en) 1978-04-04
DK138900C (da) 1979-04-30
FR2301536A1 (fr) 1976-09-17
LU74411A1 (https=) 1976-08-13
BE838879A (fr) 1976-08-24
CH626093A5 (https=) 1981-10-30
DE2508312A1 (de) 1976-09-02
SE7602109L (sv) 1976-08-25
DE2508312C2 (https=) 1987-10-29
FR2301536B1 (https=) 1979-07-27
JPS6139318B2 (https=) 1986-09-03
NL7601625A (nl) 1976-08-26

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