FR2301536A1 - Procede de preparation de nucleosides - Google Patents
Procede de preparation de nucleosidesInfo
- Publication number
- FR2301536A1 FR2301536A1 FR7605030A FR7605030A FR2301536A1 FR 2301536 A1 FR2301536 A1 FR 2301536A1 FR 7605030 A FR7605030 A FR 7605030A FR 7605030 A FR7605030 A FR 7605030A FR 2301536 A1 FR2301536 A1 FR 2301536A1
- Authority
- FR
- France
- Prior art keywords
- preparation process
- nucleoside preparation
- nucleoside
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752508312 DE2508312A1 (de) | 1975-02-24 | 1975-02-24 | Neues verfahren zur herstellung von nucleosiden |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2301536A1 true FR2301536A1 (fr) | 1976-09-17 |
FR2301536B1 FR2301536B1 (fr) | 1979-07-27 |
Family
ID=5939872
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7605030A Granted FR2301536A1 (fr) | 1975-02-24 | 1976-02-24 | Procede de preparation de nucleosides |
Country Status (12)
Country | Link |
---|---|
US (1) | US4082911A (fr) |
JP (1) | JPS51125382A (fr) |
BE (1) | BE838879A (fr) |
CA (1) | CA1065315A (fr) |
CH (1) | CH626093A5 (fr) |
DE (1) | DE2508312A1 (fr) |
DK (1) | DK138900C (fr) |
FR (1) | FR2301536A1 (fr) |
GB (1) | GB1542442A (fr) |
LU (1) | LU74411A1 (fr) |
NL (1) | NL7601625A (fr) |
SE (1) | SE7602109L (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53108986A (en) * | 1977-03-02 | 1978-09-22 | Mitsui Toatsu Chem Inc | Preparation of nucleosides and nucleotides |
DE2721466A1 (de) * | 1977-05-12 | 1978-11-16 | Robugen Gmbh | Verfahren zur herstellung von 2'-desoxyribofuranosylnucleosiden |
US4195176A (en) * | 1977-10-11 | 1980-03-25 | Warner-Lambert Company | Imidazole compounds, methods for their production and conversion of said compounds into (R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazol[4,5-d][1,3]diazepin-8-ol |
DE2757365A1 (de) * | 1977-12-20 | 1979-06-21 | Schering Ag | Neues verfahren zur herstellung von nucleosiden |
JPH029511U (fr) * | 1988-06-21 | 1990-01-22 | ||
CA2091732C (fr) * | 1992-07-08 | 1998-07-21 | Anica Markovac | Procede pour la preparation de 2-fluoro-9-(2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl)adenine |
JPH07276137A (ja) * | 1994-03-31 | 1995-10-24 | Osaka Diamond Ind Co Ltd | 切削・研削用工具 |
DE19513330A1 (de) * | 1995-04-03 | 1996-10-10 | Schering Ag | Neues Verfahren zur Herstellung von Nucleosiden |
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
CA2410579C (fr) | 2000-05-26 | 2010-04-20 | Jean-Pierre Sommadossi | Procedes et compositions de traitement des flavivirus et des pestivirus |
RS113904A (en) | 2002-06-28 | 2007-02-05 | Idenix (Cayman) Limited | 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
US7608600B2 (en) | 2002-06-28 | 2009-10-27 | Idenix Pharmaceuticals, Inc. | Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections |
CN1849142A (zh) | 2002-11-15 | 2006-10-18 | 埃迪尼克斯(开曼)有限公司 | 2′-支链核苷和黄病毒突变 |
US6887855B2 (en) * | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
US6943249B2 (en) * | 2003-03-17 | 2005-09-13 | Ash Stevens, Inc. | Methods for isolating crystalline Form I of 5-azacytidine |
US7038038B2 (en) * | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
WO2004096149A2 (fr) | 2003-04-28 | 2004-11-11 | Idenix (Cayman) Limited | Synthese de nucleosides pouvant etre mise a l'echelle industrielle |
EP2157095A3 (fr) | 2003-06-30 | 2010-09-08 | Novartis AG | Synthèse de bêta-L-2-désoxynucléosides |
AT502635A1 (de) * | 2005-11-09 | 2007-05-15 | Saischek Und Partner Meg | Neue 1,3-dithioverbindungen, verfahren zu deren herstellung und ihre verwendung |
JP5254033B2 (ja) | 2005-12-23 | 2013-08-07 | イデニク プハルマセウティカルス,インコーポレイテッド | 分岐型ヌクレオシドを調製するための合成中間体の製造方法 |
EP2050757A1 (fr) * | 2007-10-10 | 2009-04-22 | Cilag AG | Procédé de fabrication de 2' -désoxy-5-azacytidine (Décitabine) |
EP2048151A1 (fr) * | 2007-10-10 | 2009-04-15 | Cilag AG | Procédé pour la production de nucléosides par glycosylation directe de la base nucléosidique |
DK3782612T3 (da) | 2008-05-15 | 2024-01-15 | Celgene Corp | Orale formuleringer af cytidinanaloger og fremgangsmåder til anvendelse deraf |
WO2010014883A2 (fr) | 2008-08-01 | 2010-02-04 | Dr. Reddy's Laboratories Ltd. | Procédé de préparation d'azacitidine et polymorphes |
EP2520581A1 (fr) * | 2008-08-06 | 2012-11-07 | Sicor, Inc. | Methode de détermination de la pureté de la 5-Azacytidine |
CA2733591C (fr) * | 2008-08-08 | 2016-06-28 | Scinopharm Taiwan Ltd. | Procede de fabrication de nucleosides de 5-azacytosine et leurs derives |
EP2424845A4 (fr) * | 2009-04-27 | 2014-03-05 | Reddys Lab Ltd Dr | Préparation de décitabine |
BR112013025167A2 (pt) | 2011-03-31 | 2019-09-24 | Celgene Int Sarl | processo para preparar 5-azacitidina, ou um sal, solvato, hidrato, ou seu polimorfo, sal de 5-azacitidina, 5-azacitidina, ou um sal, solvato, hidrato, ou polimorfo |
CN108239128B (zh) * | 2016-12-23 | 2019-03-29 | 江苏奥赛康药业股份有限公司 | β-核苷类化合物的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3354160A (en) * | 1965-07-22 | 1967-11-21 | Hoffmann La Roche | Tri-lower alkyl-silyl-5-fluoropyrimidines |
US3352849A (en) * | 1965-10-24 | 1967-11-14 | Merck & Co Inc | 6-aza-2'-deoxyuridines |
CH541566A (de) * | 1969-04-11 | 1973-09-15 | Schering Ag | Verfahren zur Herstellung von Nucleosiden |
DE2122991C2 (de) * | 1971-05-04 | 1982-06-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden |
-
1975
- 1975-02-24 DE DE19752508312 patent/DE2508312A1/de active Granted
-
1976
- 1976-02-18 NL NL7601625A patent/NL7601625A/xx not_active Application Discontinuation
- 1976-02-23 GB GB767006A patent/GB1542442A/en not_active Expired
- 1976-02-23 LU LU74411A patent/LU74411A1/xx unknown
- 1976-02-23 CA CA246,368A patent/CA1065315A/fr not_active Expired
- 1976-02-23 US US05/660,675 patent/US4082911A/en not_active Expired - Lifetime
- 1976-02-23 SE SE7602109A patent/SE7602109L/xx unknown
- 1976-02-24 BE BE164585A patent/BE838879A/fr not_active IP Right Cessation
- 1976-02-24 JP JP51019810A patent/JPS51125382A/ja active Granted
- 1976-02-24 FR FR7605030A patent/FR2301536A1/fr active Granted
- 1976-02-24 CH CH227476A patent/CH626093A5/de not_active IP Right Cessation
- 1976-02-24 DK DK77176A patent/DK138900C/da active
Non-Patent Citations (1)
Title |
---|
ANGEW. CHEM. INTERNAT. EDIT. 14 6 1975 , PAGES 421-422) * |
Also Published As
Publication number | Publication date |
---|---|
NL7601625A (nl) | 1976-08-26 |
CA1065315A (fr) | 1979-10-30 |
DE2508312C2 (fr) | 1987-10-29 |
DK77176A (da) | 1976-08-25 |
GB1542442A (en) | 1979-03-21 |
BE838879A (fr) | 1976-08-24 |
DK138900C (da) | 1979-04-30 |
JPS6139318B2 (fr) | 1986-09-03 |
FR2301536B1 (fr) | 1979-07-27 |
SE7602109L (sv) | 1976-08-25 |
DE2508312A1 (de) | 1976-09-02 |
JPS51125382A (en) | 1976-11-01 |
DK138900B (da) | 1978-11-13 |
CH626093A5 (fr) | 1981-10-30 |
LU74411A1 (fr) | 1976-08-13 |
US4082911A (en) | 1978-04-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |