DK138900B - Fremgangsmaade til fremstilling af nucleosider - Google Patents

Fremgangsmaade til fremstilling af nucleosider

Info

Publication number
DK138900B
DK138900B DK77176AA DK77176A DK138900B DK 138900 B DK138900 B DK 138900B DK 77176A A DK77176A A DK 77176AA DK 77176 A DK77176 A DK 77176A DK 138900 B DK138900 B DK 138900B
Authority
DK
Denmark
Prior art keywords
procedure
nucleosides
making
making nucleosides
Prior art date
Application number
DK77176AA
Other languages
English (en)
Other versions
DK138900C (da
DK77176A (da
Inventor
H Vorbrueggen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK77176A publication Critical patent/DK77176A/da
Publication of DK138900B publication Critical patent/DK138900B/da
Application granted granted Critical
Publication of DK138900C publication Critical patent/DK138900C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
DK77176A 1975-02-24 1976-02-24 Fremgangsmaade til fremstilling af nucleosider DK138900C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752508312 DE2508312A1 (de) 1975-02-24 1975-02-24 Neues verfahren zur herstellung von nucleosiden

Publications (3)

Publication Number Publication Date
DK77176A DK77176A (da) 1976-08-25
DK138900B true DK138900B (da) 1978-11-13
DK138900C DK138900C (da) 1979-04-30

Family

ID=5939872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK77176A DK138900C (da) 1975-02-24 1976-02-24 Fremgangsmaade til fremstilling af nucleosider

Country Status (12)

Country Link
US (1) US4082911A (da)
JP (1) JPS51125382A (da)
BE (1) BE838879A (da)
CA (1) CA1065315A (da)
CH (1) CH626093A5 (da)
DE (1) DE2508312A1 (da)
DK (1) DK138900C (da)
FR (1) FR2301536A1 (da)
GB (1) GB1542442A (da)
LU (1) LU74411A1 (da)
NL (1) NL7601625A (da)
SE (1) SE7602109L (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53108986A (en) * 1977-03-02 1978-09-22 Mitsui Toatsu Chem Inc Preparation of nucleosides and nucleotides
DE2721466A1 (de) * 1977-05-12 1978-11-16 Robugen Gmbh Verfahren zur herstellung von 2'-desoxyribofuranosylnucleosiden
US4195176A (en) * 1977-10-11 1980-03-25 Warner-Lambert Company Imidazole compounds, methods for their production and conversion of said compounds into (R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazol[4,5-d][1,3]diazepin-8-ol
DE2757365A1 (de) * 1977-12-20 1979-06-21 Schering Ag Neues verfahren zur herstellung von nucleosiden
JPH029511U (da) * 1988-06-21 1990-01-22
CA2091732C (en) * 1992-07-08 1998-07-21 Anica Markovac A process for the preparation of 2-fluoro-9-(2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl) adenine
JPH07276137A (ja) * 1994-03-31 1995-10-24 Osaka Diamond Ind Co Ltd 切削・研削用工具
DE19513330A1 (de) * 1995-04-03 1996-10-10 Schering Ag Neues Verfahren zur Herstellung von Nucleosiden
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
NZ547204A (en) 2000-05-26 2008-01-31 Idenix Cayman Ltd Methods and compositions for treating flaviviruses and pestiviruses
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
US7456155B2 (en) 2002-06-28 2008-11-25 Idenix Pharmaceuticals, Inc. 2′-C-methyl-3′-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
HUE033832T2 (en) 2002-11-15 2018-01-29 Idenix Pharmaceuticals Llc 2'-methyl nucleosides in combination with interferon and Flaviviridae mutation
US7038038B2 (en) * 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US6943249B2 (en) 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
WO2004096149A2 (en) 2003-04-28 2004-11-11 Idenix (Cayman) Limited Industrially scalable nucleoside synthesis
EP1639121A4 (en) 2003-06-30 2008-04-16 Idenix Cayman Ltd SYNTHESIS OF BETA-L-2-DESOXYNUCLEOSIDES
AT502635A1 (de) * 2005-11-09 2007-05-15 Saischek Und Partner Meg Neue 1,3-dithioverbindungen, verfahren zu deren herstellung und ihre verwendung
CA2634749C (en) 2005-12-23 2014-08-19 Idenix Pharmaceuticals, Inc. Process for preparing a synthetic intermediate for preparation of branched nucleosides
EP2048151A1 (en) * 2007-10-10 2009-04-15 Cilag AG Method for producing nucleosides by direct glycosylation of the nucleoside base
EP2050757A1 (en) * 2007-10-10 2009-04-22 Cilag AG Method of producing 2' -deoxy-5-azacytidine (Decitabine)
WO2009139888A1 (en) 2008-05-15 2009-11-19 Celgene Corporation Oral formulations of cytidine analogs and methods of use thereof
EP2321302B1 (en) * 2008-08-01 2014-10-29 Dr. Reddy's Laboratories Ltd. Azacitidine process and polymorphs
US20100035354A1 (en) * 2008-08-06 2010-02-11 Ettore Bigatti Process for preparing azacytidine intermediate
AR073003A1 (es) * 2008-08-08 2010-10-06 Scinopharm Taiwan Ltd Proceso para preparar 5-azacitosina nucleosidos y sus derivados
AR076418A1 (es) * 2009-04-27 2011-06-08 Reddys Lab Inc Dr Preparacion de decitabina
MX2013010945A (es) 2011-03-31 2014-03-12 Celgene Internat Sarl Sintesis de 5 - azacitidina.
CN108239128B (zh) * 2016-12-23 2019-03-29 江苏奥赛康药业股份有限公司 β-核苷类化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
US3352849A (en) * 1965-10-24 1967-11-14 Merck & Co Inc 6-aza-2'-deoxyuridines
CH541566A (de) * 1969-04-11 1973-09-15 Schering Ag Verfahren zur Herstellung von Nucleosiden
DE2122991C2 (de) * 1971-05-04 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden

Also Published As

Publication number Publication date
DK138900C (da) 1979-04-30
CH626093A5 (da) 1981-10-30
JPS51125382A (en) 1976-11-01
GB1542442A (en) 1979-03-21
JPS6139318B2 (da) 1986-09-03
NL7601625A (nl) 1976-08-26
DE2508312A1 (de) 1976-09-02
SE7602109L (sv) 1976-08-25
FR2301536A1 (fr) 1976-09-17
CA1065315A (en) 1979-10-30
US4082911A (en) 1978-04-04
FR2301536B1 (da) 1979-07-27
DK77176A (da) 1976-08-25
LU74411A1 (da) 1976-08-13
BE838879A (fr) 1976-08-24
DE2508312C2 (da) 1987-10-29

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