DK484576A - Fremgangsmade til fremstilling af 2-aroyl-3-phenyl-benzothiophenforbindelser - Google Patents
Fremgangsmade til fremstilling af 2-aroyl-3-phenyl-benzothiophenforbindelserInfo
- Publication number
- DK484576A DK484576A DK484576A DK484576A DK484576A DK 484576 A DK484576 A DK 484576A DK 484576 A DK484576 A DK 484576A DK 484576 A DK484576 A DK 484576A DK 484576 A DK484576 A DK 484576A
- Authority
- DK
- Denmark
- Prior art keywords
- aroyl
- phenyl
- procedure
- making
- benzothiophene compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62600975A | 1975-10-28 | 1975-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK484576A true DK484576A (da) | 1977-04-29 |
Family
ID=24508577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK484576A DK484576A (da) | 1975-10-28 | 1976-10-27 | Fremgangsmade til fremstilling af 2-aroyl-3-phenyl-benzothiophenforbindelser |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4075227A (da) |
| JP (1) | JPS5253852A (da) |
| AR (1) | AR216451A1 (da) |
| AT (1) | AT352709B (da) |
| AU (1) | AU509682B2 (da) |
| BE (1) | BE847718A (da) |
| BG (1) | BG27554A3 (da) |
| CA (1) | CA1064031A (da) |
| CH (1) | CH626360A5 (da) |
| CS (1) | CS196328B2 (da) |
| DD (1) | DD127463A5 (da) |
| DE (1) | DE2647864C2 (da) |
| DK (1) | DK484576A (da) |
| ES (1) | ES452737A1 (da) |
| FR (1) | FR2329270A1 (da) |
| GB (1) | GB1572506A (da) |
| GR (1) | GR62400B (da) |
| IE (1) | IE43970B1 (da) |
| IL (1) | IL50413A (da) |
| MX (1) | MX3972E (da) |
| NL (1) | NL7611972A (da) |
| NZ (1) | NZ182428A (da) |
| PL (1) | PL109366B1 (da) |
| PT (1) | PT65753B (da) |
| RO (1) | RO70768A (da) |
| SE (1) | SE427035B (da) |
| ZA (1) | ZA766442B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| US4436748A (en) | 1980-10-20 | 1984-03-13 | Hoechst-Roussel Pharmaceuticals Inc. | Benzo[b]thiophenes |
| US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US4528399A (en) * | 1981-04-22 | 1985-07-09 | Hoechst-Roussel Pharmaceuticals Inc. | Benzo[b]thiophenes intermediates |
| US5354861A (en) * | 1992-11-04 | 1994-10-11 | National University Of Singapore | 2-(benzyl)-3-arylbenzofurans as antitumour and hypocholesterolemic agents |
| IL109990A (en) * | 1993-06-21 | 1999-06-20 | Lilly Co Eli | Materials and methods for screening anti-osteoporosis agents |
| US5523416A (en) * | 1994-07-22 | 1996-06-04 | Eli Lilly And Company | Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes |
| US5552401A (en) * | 1995-02-28 | 1996-09-03 | Eli Lilly And Company | 2-benzyl-3-arylbenzothiophenes |
| ZA9710262B (en) * | 1996-11-19 | 1999-05-13 | Lilly Co Eli | Process for the synthesis of benzothiophenes |
| US5908859A (en) * | 1997-08-11 | 1999-06-01 | Eli Lilly And Company | Benzothiophenes for inhibiting hyperlipidemia |
| US6107346A (en) * | 1997-08-11 | 2000-08-22 | Eli Lilly And Company | Methods for treating hyperlipidemia |
| US7091199B1 (en) | 1999-09-14 | 2006-08-15 | Aventis Pharmaceuticals Inc. | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists |
| US7253165B2 (en) * | 1999-09-14 | 2007-08-07 | Aventis Pharmaceuticals Inc. | Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists |
| US7125903B1 (en) | 1999-09-14 | 2006-10-24 | Aventis Pharmaceuticals Inc. | Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists |
| JP4583688B2 (ja) * | 1999-10-04 | 2010-11-17 | 日本曹達株式会社 | フェノール性化合物及びそれを用いた記録材料 |
| WO2002042289A2 (en) * | 2000-11-27 | 2002-05-30 | Eli Lilly And Company | Process for preparing 3-aryl-benzo[b]thiophenes |
| AUPR283801A0 (en) * | 2001-02-01 | 2001-03-01 | Australian National University, The | Chemical compounds and methods |
| JP3904517B2 (ja) * | 2001-04-04 | 2007-04-11 | 日本曹達株式会社 | 組成物、記録材料及び記録シート |
| ATE321754T1 (de) * | 2001-05-22 | 2006-04-15 | Lilly Co Eli | 2-substituierte 1,2,3,4-tetrahydrochinoline und derivate davon, zusammensetzungen und verfahren |
| JP2004531559A (ja) * | 2001-05-22 | 2004-10-14 | イーライ・リリー・アンド・カンパニー | エストロゲン欠乏または内因性エストロゲンに対する異常な生理反応に関連する疾患を抑制するためのテトラヒドロキノリン誘導体 |
| DE10309645A1 (de) | 2003-03-06 | 2004-09-16 | Basf Ag | Verfahren zur Herstellung von a-(3-Arylthio)-acetophenonen |
| CA3052810A1 (en) | 2017-02-10 | 2018-08-16 | G1 Therapeutics, Inc. | Benzothiophene estrogen receptor modulators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1456323A (en) * | 1974-06-06 | 1976-11-24 | Labaz | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
| US3947470A (en) * | 1974-06-20 | 1976-03-30 | Smithkline Corporation | Substituted benzofurans and benzothiophenes |
| US4001426A (en) * | 1974-10-17 | 1977-01-04 | Smithkline Corporation | Substituted benzofurans and benzothiophenes |
| US3983245A (en) * | 1975-02-06 | 1976-09-28 | Smithkline Corporation | Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes |
-
1976
- 1976-09-02 AU AU17408/76A patent/AU509682B2/en not_active Expired
- 1976-09-05 IL IL50413A patent/IL50413A/xx unknown
- 1976-10-21 MX MX764992U patent/MX3972E/es unknown
- 1976-10-21 CA CA263,897A patent/CA1064031A/en not_active Expired
- 1976-10-22 DE DE2647864A patent/DE2647864C2/de not_active Expired
- 1976-10-25 PT PT65753A patent/PT65753B/pt unknown
- 1976-10-25 GR GR52003A patent/GR62400B/el unknown
- 1976-10-25 GB GB44200/76A patent/GB1572506A/en not_active Expired
- 1976-10-26 ES ES452737A patent/ES452737A1/es not_active Expired
- 1976-10-26 RO RO7688226A patent/RO70768A/ro unknown
- 1976-10-27 ZA ZA00766442A patent/ZA766442B/xx unknown
- 1976-10-27 NZ NZ182428A patent/NZ182428A/xx unknown
- 1976-10-27 IE IE2370/76A patent/IE43970B1/en unknown
- 1976-10-27 DK DK484576A patent/DK484576A/da not_active Application Discontinuation
- 1976-10-27 CH CH1355376A patent/CH626360A5/de not_active IP Right Cessation
- 1976-10-27 JP JP51129998A patent/JPS5253852A/ja active Granted
- 1976-10-27 SE SE7611954A patent/SE427035B/xx unknown
- 1976-10-28 BG BG7634551A patent/BG27554A3/xx unknown
- 1976-10-28 DD DD195510A patent/DD127463A5/xx unknown
- 1976-10-28 BE BE1007724A patent/BE847718A/xx not_active IP Right Cessation
- 1976-10-28 CS CS766973A patent/CS196328B2/cs unknown
- 1976-10-28 PL PL1976193328A patent/PL109366B1/pl unknown
- 1976-10-28 FR FR7632513A patent/FR2329270A1/fr active Granted
- 1976-10-28 NL NL7611972A patent/NL7611972A/xx not_active Application Discontinuation
- 1976-10-28 AT AT800776A patent/AT352709B/de not_active IP Right Cessation
- 1976-10-28 AR AR265276A patent/AR216451A1/es active
- 1976-11-22 US US05/743,819 patent/US4075227A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AT352709B (de) | 1979-10-10 |
| BE847718A (fr) | 1977-04-28 |
| GB1572506A (en) | 1980-07-30 |
| DE2647864A1 (de) | 1977-05-12 |
| SE7611954L (sv) | 1977-04-29 |
| SE427035B (sv) | 1983-02-28 |
| JPS5253852A (en) | 1977-04-30 |
| US4075227A (en) | 1978-02-21 |
| IE43970B1 (en) | 1981-07-15 |
| GR62400B (en) | 1979-04-10 |
| RO70768A (ro) | 1982-10-26 |
| CS196328B2 (en) | 1980-03-31 |
| CA1064031A (en) | 1979-10-09 |
| PL109366B1 (en) | 1980-05-31 |
| MX3972E (es) | 1981-10-20 |
| AR216451A1 (es) | 1979-12-28 |
| BG27554A3 (en) | 1979-11-12 |
| CH626360A5 (da) | 1981-11-13 |
| DE2647864C2 (de) | 1985-04-25 |
| FR2329270A1 (fr) | 1977-05-27 |
| PT65753A (en) | 1976-11-01 |
| NL7611972A (nl) | 1977-05-02 |
| AU1740876A (en) | 1978-03-09 |
| FR2329270B1 (da) | 1979-07-27 |
| AU509682B2 (en) | 1980-05-22 |
| ZA766442B (en) | 1978-06-28 |
| IL50413A (en) | 1980-05-30 |
| IE43970L (en) | 1977-04-28 |
| ES452737A1 (es) | 1978-01-01 |
| DD127463A5 (da) | 1977-09-28 |
| JPS61344B2 (da) | 1986-01-08 |
| NZ182428A (en) | 1978-11-13 |
| PT65753B (en) | 1978-04-20 |
| IL50413A0 (en) | 1976-11-30 |
| ATA800776A (de) | 1979-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK143706C (da) | Fremgangsmaade til fremstilling af svovlholdige organosiliciumforbindelser | |
| DK49676A (da) | Fremgangsmade til fremstilling af hypolipidemiske midler | |
| DK81277A (da) | Fremgangsmade til fremstilling af bis-pyridinium-forbindelser | |
| DK484576A (da) | Fremgangsmade til fremstilling af 2-aroyl-3-phenyl-benzothiophenforbindelser | |
| DK87876A (da) | Fremgangsmade til fremstilling af n-acyl-l-metionin | |
| DK442476A (da) | Fremgangsmade til fremstilling af pyrimidinforbindelser | |
| DK243176A (da) | Fremgangsmade til fremstilling af polycliske forbindelser | |
| DK517776A (da) | Fremgangsmade til femstilling af heterocycliske forbindelser | |
| DK164476A (da) | Fremgangsmade til fremstilling af piperazinylpyrazinforbindelser | |
| DK93976A (da) | Fremgangsmade til fremstilling af butyrophenonforbindelser | |
| DK324776A (da) | Fremgangsmade til fremstilling af 3-cyanoimino-3-aminopropionitriler | |
| DK123277A (da) | Fremgangsmade til fremstilling af 3-halogenmethyl-3-cephem-forbindelser | |
| DK305876A (da) | Fremgangsmade til fremstilling af l-pyroglutamyl-l-prolinamid | |
| DK318876A (da) | Fremgangsmade til fremstilling af prostaglandinanaloge | |
| DK283476A (da) | Fremgangsmade til fremstilling af beta-acylpyrroler | |
| DK143281C (da) | Fremgangsmaade til fremstilling af phosphitchlorider | |
| DK143137C (da) | Fremgangsmaade til fremstilling af phosphitchlorider | |
| DK527476A (da) | Fremgangsmade til fremstilling af organiske forbindelser | |
| DK287576A (da) | Fremgangsmade til fremstilling af araliphatiske dihalogenforbindelser | |
| DK555375A (da) | Fremgangsmade til fremstilling af heterocykliske forbindelser | |
| DK484776A (da) | Fremgangsmade til fremstilling af aroylphenylnaphthalen-forbindelser | |
| DK342976A (da) | Fremgangsmade til fremstilling af organiske forbindelser | |
| DK98176A (da) | Fremgangsmade til fremstilling af organiske forbindelser | |
| DK401476A (da) | Fremgangsmade til fremstilling af benzocycloheptapyridinforbindelser | |
| DK535175A (da) | Fremgangsmade til fremstilling af chromonforbindelser |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |