|
US5997873A
(en)
*
|
1994-01-13 |
1999-12-07 |
Mount Sinai School Of Medicine Of The City University Of New York |
Method of preparation of heat shock protein 70-peptide complexes
|
|
US5750119A
(en)
*
|
1994-01-13 |
1998-05-12 |
Mount Sinai School Of Medicine Of The City University Of New York |
Immunotherapeutic stress protein-peptide complexes against cancer
|
|
US5961979A
(en)
|
1994-03-16 |
1999-10-05 |
Mount Sinai School Of Medicine Of The City University Of New York |
Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
|
|
CA2229543A1
(en)
*
|
1995-08-18 |
1997-02-27 |
Sloan-Kettering Institute For Cancer Research |
Heat shock protein-based vaccines and immunotherapies
|
|
US6719974B1
(en)
*
|
1995-08-18 |
2004-04-13 |
Sloan-Kettering Institute For Cancer Research |
Heat shock protein-based vaccines and immunotherapies
|
|
US6331299B1
(en)
|
1995-08-18 |
2001-12-18 |
Sloan-Kettering Institute For Cancer Research |
Method for treatment of cancer and infectious disease and compositions useful in same
|
|
US6761892B1
(en)
*
|
1995-08-18 |
2004-07-13 |
Sloan-Kettering Institute For Cancer Research |
Heat shock protein-based vaccines and immunotherapies
|
|
US6773707B1
(en)
|
1995-08-18 |
2004-08-10 |
Sloan-Kettering Institute For Cancer Research |
Heat shock protein-based vaccines and immunotherapies
|
|
US5985270A
(en)
*
|
1995-09-13 |
1999-11-16 |
Fordham University |
Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
|
|
US5935576A
(en)
|
1995-09-13 |
1999-08-10 |
Fordham University |
Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
|
|
US5837251A
(en)
|
1995-09-13 |
1998-11-17 |
Fordham University |
Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases
|
|
IN183280B
(enExample)
|
1996-09-20 |
1999-10-30 |
Univ New Mexico |
|
|
US7157089B1
(en)
|
1996-11-26 |
2007-01-02 |
Stressgen Biotechnologies Corporation |
Immune responses using compositions containing stress proteins
|
|
US6017540A
(en)
|
1997-02-07 |
2000-01-25 |
Fordham University |
Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
|
|
CA2298840A1
(en)
|
1997-08-05 |
1999-02-18 |
Stressgen Biotechnologies Corporation |
Immune responses against hpv antigens elicited by compositions comprising an hpv antigen and a stress protein or an expression vector capable of expression of these proteins
|
|
EP1027070A4
(en)
*
|
1997-10-31 |
2004-08-18 |
Sloan Kettering Institutefor C |
CONJUGATES FROM HEAT SHOCK PROTEIN-BINDING PEPTIDES
|
|
US5948646A
(en)
|
1997-12-11 |
1999-09-07 |
Fordham University |
Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
|
|
ES2355483T3
(es)
*
|
1998-02-20 |
2011-03-28 |
University Of Miami |
Complejo de proteina de choque térmico modificada-péptido antigénico.
|
|
US7014848B1
(en)
|
1998-03-20 |
2006-03-21 |
Genzyme Corporation |
Enhanced anti-tumor immunity
|
|
CA2322660A1
(en)
*
|
1998-03-20 |
1999-09-23 |
Genzyme Corporation |
Enhanced anti-tumor immunity
|
|
EP1066370A1
(en)
|
1998-03-30 |
2001-01-10 |
I.D.M. Immuno-Designed Molecules |
Stimulated monocyte derived cells, their preparation and uses
|
|
US20020168347A1
(en)
*
|
1998-04-09 |
2002-11-14 |
Jacques Bartholeyns |
Use of monocytes derived cells, antigens and antibodies for optimal induction of immunotherapeutic efficiency
|
|
US6858386B1
(en)
*
|
1998-05-21 |
2005-02-22 |
Diadexus, Inc. |
Method of diagnosing, monitoring, staging, imaging and treating colon cancer
|
|
US6949339B1
(en)
|
1998-05-21 |
2005-09-27 |
Diadexus, Inc. |
Method of diagnosing, monitoring, and staging colon cancer
|
|
US20020142974A1
(en)
*
|
1998-09-11 |
2002-10-03 |
Leonard D. Kohn |
Immune activation by double-stranded polynucleotides
|
|
US6797480B1
(en)
|
1998-10-05 |
2004-09-28 |
University Of Connecticut Health Center |
Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents
|
|
ES2279647T3
(es)
*
|
1998-11-10 |
2007-08-16 |
Emory University |
Reguladores mitogenicos.
|
|
US6730302B1
(en)
*
|
1998-11-24 |
2004-05-04 |
Bristol-Myers Squibb Company |
Intracellular targeted delivery of compounds by 70 kD heat shock protein
|
|
CN1367875A
(zh)
*
|
1999-07-08 |
2002-09-04 |
斯特思吉生物技术公司 |
活体外th1一样反应的诱导方法
|
|
AUPQ233799A0
(en)
|
1999-08-19 |
1999-09-09 |
Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales |
Recombinant sub-unit vaccine
|
|
GB9919733D0
(en)
*
|
1999-08-19 |
1999-10-20 |
Colaco Camilo |
Vaccines against intracellular pathogens
|
|
AU7743100A
(en)
|
1999-09-30 |
2001-04-30 |
Corixa Corporation |
Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
|
|
US7378096B2
(en)
|
1999-09-30 |
2008-05-27 |
Health Research, Inc. |
Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
|
|
JP3524537B2
(ja)
*
|
1999-11-22 |
2004-05-10 |
ディアデクサス インコーポレーテッド |
癌の診断、モニタリング、ステージング、イメージングおよび処置のための新規方法
|
|
US7238471B1
(en)
*
|
1999-11-23 |
2007-07-03 |
Diadexus, Inc. |
Method of diagnosing, monitoring, staging, imaging and treating breast cancer
|
|
US20020048777A1
(en)
*
|
1999-12-06 |
2002-04-25 |
Shujath Ali |
Method of diagnosing monitoring, staging, imaging and treating prostate cancer
|
|
IL150113A0
(en)
*
|
1999-12-15 |
2002-12-01 |
Peptor Ltd |
Fragments and antagonists of heat shock protein 60
|
|
JP2004501061A
(ja)
*
|
1999-12-15 |
2004-01-15 |
ペプトル・リミテツド |
熱ショックタンパク質60のフラグメントおよびアンタゴニスト
|
|
GB0004547D0
(en)
*
|
2000-02-23 |
2000-04-19 |
Immunobiology Ltd |
Screening method for novel vaccine candidates and compositions obtained thereby
|
|
AU6523901A
(en)
*
|
2000-05-26 |
2001-12-11 |
Diadexus Inc |
Method of diagnosing, monitoring, staging, imaging and treating colon cancer
|
|
US7186515B1
(en)
|
2000-06-02 |
2007-03-06 |
University Of Connecticut Health Center |
Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof
|
|
US7179462B2
(en)
|
2000-06-02 |
2007-02-20 |
University Of Connecticut Health Center |
α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof
|
|
US7449557B2
(en)
|
2000-06-02 |
2008-11-11 |
University Of Connecticut Health Center |
Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
|
|
BR0111956A
(pt)
*
|
2000-06-26 |
2003-05-13 |
Stressgen Biotechnologies Corp |
Tratamento do vìrus do papiloma humano
|
|
EP1322747A4
(en)
*
|
2000-09-15 |
2004-12-29 |
Univ Connecticut Health Ct |
IMPROVED FORMULATIONS USING THERMAL SHOCK / STRESS PEPTIDE-PROTEIN COMPLEXES
|
|
US20020172682A1
(en)
*
|
2000-10-20 |
2002-11-21 |
University Of Connecticut Health Center |
Using heat shock proteins to increase immune response
|
|
US7132109B1
(en)
|
2000-10-20 |
2006-11-07 |
University Of Connecticut Health Center |
Using heat shock proteins to increase immune response
|
|
EP1209226A3
(en)
*
|
2000-11-07 |
2002-06-05 |
GSF-Forschungszentrum für Umwelt und Gesundheit GmbH |
Maturation of dendritic cells by recombinant heat shock protein 70 (hsp70)
|
|
US6892140B1
(en)
|
2000-11-27 |
2005-05-10 |
Enteron, Inc. |
Immunogenic cancer peptides and uses thereof
|
|
EP1354208A2
(en)
|
2001-01-19 |
2003-10-22 |
Cambridge Scientific, Inc. |
Methods of diagnosis and treatment of osteoporosis
|
|
MXPA03006971A
(es)
|
2001-02-05 |
2004-05-05 |
Stressgen Biotechnologies Corp |
Tratamiento del virus de hepatitis b.
|
|
US6855925B2
(en)
*
|
2001-02-14 |
2005-02-15 |
Picoliter Inc. |
Methods, devices, and systems using acoustic ejection for depositing fluid droplets on a sample surface for analysis
|
|
US20040071671A1
(en)
|
2001-02-20 |
2004-04-15 |
Leturcq Didier J. |
Cell therapy method for the treatment of tumors
|
|
CA2698079C
(en)
|
2001-02-20 |
2015-01-13 |
Ortho-Mcneil Pharmaceutical, Inc. |
A cell therapy method for the treatment of tumors
|
|
US7189513B2
(en)
*
|
2001-03-23 |
2007-03-13 |
The United States Of America As Represented By The Department Of Health And Human Services |
Human papilloma virus immunoreactive peptides
|
|
IL160511A0
(en)
*
|
2001-08-20 |
2004-07-25 |
Univ Connecticut Health Ct |
Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin useful for the treatment of cancer and infectious disease
|
|
US20030211971A1
(en)
*
|
2001-09-17 |
2003-11-13 |
Srivastava Pramod K. |
Compositions and methods for prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with compositions comprising unfractionated cellular proteins
|
|
CA2460396A1
(en)
|
2001-10-01 |
2003-04-10 |
Duke University |
Isolated grp94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same
|
|
US20030194409A1
(en)
*
|
2002-01-17 |
2003-10-16 |
Rothman James E. |
Conjugate heat shock protein-binding peptides
|
|
EP1575479A4
(en)
|
2002-01-31 |
2006-10-25 |
Develogen Israel Ltd |
HSP-PEPTIDES AND ANALOGUES FOR MODULATING IMMUNE RESPONSES ON ANY PRESENTING CELLS
|
|
US7118753B2
(en)
*
|
2002-02-08 |
2006-10-10 |
Anawrahta Biotech Co., Ltd. |
Enhancing cell-based immunotherapy
|
|
CN1780919A
(zh)
*
|
2002-02-28 |
2006-05-31 |
抗基因公司 |
基于应激蛋白寡聚化的方法和产品
|
|
US6984389B2
(en)
|
2002-04-25 |
2006-01-10 |
University Of Connecticut Health Center |
Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
|
|
RU2376029C2
(ru)
|
2002-04-25 |
2009-12-20 |
Юниверсити Оф Коннектикут Хелт Сентер |
Применение белков теплового шока для улучшения терапевтического эффекта невакцинного лечебного воздействия
|
|
RU2375077C2
(ru)
*
|
2002-05-02 |
2009-12-10 |
Юниверсити Оф Коннектикут Хелт Сентер |
Использование белков теплового шока для повышения эффективности терапий антителами
|
|
ES2369077T3
(es)
*
|
2002-06-06 |
2011-11-25 |
Immunicum Ab |
Nuevo procedimiento y composición para producir una vacuna alogénica celular.
|
|
AU2003287048A1
(en)
*
|
2002-10-07 |
2004-05-04 |
Antigenics, Inc. |
Heat shock protein binding fragments of cd91, and uses thereof
|
|
US7420037B2
(en)
|
2003-02-13 |
2008-09-02 |
Antigenics Inc. |
Heat shock protein-based vaccines and immunotherapies
|
|
EP1603391A4
(en)
*
|
2003-02-20 |
2009-06-24 |
Univ Connecticut Health Ct |
METHODS OF USING ALPHA-2 STRESS OR MACROGLOBULIN PROTEIN-CONTAINING COMPOSITIONS IN THE TREATMENT OF CANCER AND INFECTIOUS DISEASE
|
|
EP1601756B1
(en)
|
2003-02-20 |
2010-12-15 |
University of Connecticut Health Center |
Methods for the preparation of alpha (2) macroglobulin-antigenic molecule complexes
|
|
CA2517396A1
(en)
*
|
2003-02-28 |
2005-03-10 |
Antigenics Inc. |
Use of lectins to promote oligomerization of glycoproteins and antigenic molecules
|
|
US7309491B2
(en)
*
|
2003-04-11 |
2007-12-18 |
Antigenics Inc. |
Heat shock protein-based vaccines and immunotherapies
|
|
AU2004274430A1
(en)
*
|
2003-09-12 |
2005-03-31 |
Antigenics, Inc. |
Vaccine for treatment and prevention of herpes simplex virus infection
|
|
US20080089875A1
(en)
*
|
2006-10-13 |
2008-04-17 |
Zheng Cui |
Methods and compositions for the treatment of cancer
|
|
US8475785B2
(en)
|
2008-03-03 |
2013-07-02 |
The University Of Miami |
Allogeneic cancer cell-based immunotherapy
|
|
CN102036677A
(zh)
|
2008-03-20 |
2011-04-27 |
迈阿密大学 |
热休克蛋白gp96的疫苗接种及其使用方法
|
|
HUE025852T2
(en)
|
2008-06-26 |
2016-04-28 |
Orphazyme Aps |
Use of HSP70 to regulate enzyme activity
|
|
WO2010002983A2
(en)
*
|
2008-07-03 |
2010-01-07 |
Duke University |
Composition and methods for eliciting an immune response
|
|
US20110223196A1
(en)
*
|
2008-11-21 |
2011-09-15 |
University Of Miami |
Hiv/siv vaccines for the generation of mucosal and systemic immunity
|
|
BRPI0923249A2
(pt)
|
2008-12-03 |
2016-01-26 |
Inst Pasteur Ct Nat De La Rech Scient Cnrs |
uso de modulinas solúveis em fenol no desenvolvimento de vacinas
|
|
US20120100173A1
(en)
|
2009-04-03 |
2012-04-26 |
Agenus Inc. |
Methods for preparing and using multichaperone-antigen complexes
|
|
GB0916557D0
(en)
|
2009-09-21 |
2009-10-28 |
Health Prot Agency |
Commensal neisserial stress protein complexes
|
|
CA2793959C
(en)
|
2010-03-25 |
2019-06-04 |
Oregon Health & Science University |
Cmv glycoproteins and recombinant vectors
|
|
JP2010235611A
(ja)
*
|
2010-05-10 |
2010-10-21 |
Ortho Mcneil Pharmaceut Inc |
腫瘍の治療のための細胞治療方法
|
|
RU2013125923A
(ru)
|
2010-11-30 |
2015-01-10 |
Орфазиме Апс |
СПОСОБЫ УВЕЛИЧЕНИЯ ВНУТРИКЛЕТОЧНОЙ АКТИВНОСТИ Hsp70
|
|
WO2012123269A1
(en)
|
2011-03-11 |
2012-09-20 |
Proyecto De Biomedicina Cima, S.L. |
Immunogenic compositions and methods for their use
|
|
EP2505640A1
(en)
|
2011-03-29 |
2012-10-03 |
Neo Virnatech, S.L. |
Vaccine compositions for birnavirus-borne diseases
|
|
SMT201800284T1
(it)
|
2011-06-10 |
2018-07-17 |
Univ Oregon Health & Science |
Glicoproteine cmv e vettori ricombinanti
|
|
AU2012216792A1
(en)
|
2011-09-12 |
2013-03-28 |
International Aids Vaccine Initiative |
Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
|
|
EP2586461A1
(en)
|
2011-10-27 |
2013-05-01 |
Christopher L. Parks |
Viral particles derived from an enveloped virus
|
|
ES2631608T3
(es)
|
2012-06-27 |
2017-09-01 |
International Aids Vaccine Initiative |
Variante de la glicoproteína Env del VIH-1
|
|
EP2848937A1
(en)
|
2013-09-05 |
2015-03-18 |
International Aids Vaccine Initiative |
Methods of identifying novel HIV-1 immunogens
|
|
US10058604B2
(en)
|
2013-10-07 |
2018-08-28 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
|
KR20250069686A
(ko)
|
2014-09-15 |
2025-05-19 |
제브라 덴마크 에이/에스 |
아리모클로몰 제제
|
|
BR112017016681A2
(pt)
|
2015-02-06 |
2018-04-10 |
Heat Biologics Inc |
vetor de coexpressão de vacina e moléculas coestimulatórias
|
|
US10174292B2
(en)
|
2015-03-20 |
2019-01-08 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
|
US9931394B2
(en)
|
2015-03-23 |
2018-04-03 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
|
IL293135A
(en)
|
2015-05-13 |
2022-07-01 |
Agenus Inc |
Composition comprising at least two different complexes of a purified stress protein bound to an antigenic peptide
|
|
CN105176957A
(zh)
*
|
2015-10-09 |
2015-12-23 |
深圳市康尔诺生物技术有限公司 |
肾癌相关肽和热休克蛋白形成的复合物及其应用
|
|
EP3442530A1
(en)
|
2016-04-13 |
2019-02-20 |
Orphazyme A/S |
Heat shock proteins and cholesterol homeostasis
|
|
ES2831764T3
(es)
|
2016-04-29 |
2021-06-09 |
Orphazyme As |
Arimoclomol para el tratamiento de trastornos asociados a glucocerebrosidasa
|
|
US11666649B2
(en)
|
2016-10-11 |
2023-06-06 |
University Of Miami |
Vectors and vaccine cells for immunity against Zika virus
|
|
WO2018162450A1
(en)
|
2017-03-06 |
2018-09-13 |
Fundación Para La Investigación Médica Aplicada |
New inmunostimulatory compositions comprising an entity of cold inducible rna-binding protein with an antigen for the activation of dendritic cells
|
|
CA3058938A1
(en)
|
2017-04-04 |
2018-10-11 |
Heat Biologics, Inc. |
Intratumoral vaccination
|
|
PE20200303A1
(es)
|
2017-05-24 |
2020-02-06 |
Novartis Ag |
Proteinas de anticuerpo injertadas con citocina y metodos de uso en el tratamiento del cancer
|
|
CN112218883A
(zh)
|
2018-04-26 |
2021-01-12 |
艾吉纳斯公司 |
热休克蛋白结合肽组合物及其使用方法
|
|
CA3202568A1
(en)
|
2020-11-19 |
2022-05-27 |
Zevra Denmark A/S |
Processes for preparing arimoclomol citrate and intermediates thereof
|