|
US7115728B1
(en)
|
1995-01-30 |
2006-10-03 |
Ligand Pharmaceutical Incorporated |
Human peroxisome proliferator activated receptor γ
|
|
AU4050797A
(en)
*
|
1996-08-02 |
1998-02-25 |
Ligand Pharmaceuticals Incorporated |
Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators
|
|
WO1998020871A1
(en)
*
|
1996-11-08 |
1998-05-22 |
Nippon Chemiphar Co., Ltd. |
Visceral fat lowering agent
|
|
ATE462433T1
(de)
*
|
1996-12-11 |
2010-04-15 |
Dana Farber Cancer Inst Inc |
Methoden und pharmazeutische zusammensetzungen zur inhibition des tumorwachstums
|
|
EP1005344A4
(en)
*
|
1996-12-31 |
2003-03-19 |
Salk Inst For Biological Studi |
TREATMENT OF LIPOSARCOMES USING A COMBINATION OF THIAZOLIDINEDIONES AND SELECTIVE AGONISTS OF RETINO X RECEPTORS
|
|
GB9712866D0
(en)
*
|
1997-06-18 |
1997-08-20 |
Smithkline Beecham Plc |
Novel method of treatment
|
|
WO1999004815A1
(fr)
*
|
1997-07-24 |
1999-02-04 |
Yamanouchi Pharmaceutical Co., Ltd. |
Compositions medicinales hypocholesterolemiantes
|
|
WO1999005161A1
(en)
|
1997-07-25 |
1999-02-04 |
Ligand Pharmaceuticals Incorporated |
HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR
|
|
FR2767058B1
(fr)
*
|
1997-08-05 |
2000-05-05 |
Centre Nat Rech Scient |
Utilisation d'un compose de type retinoide, notamment l'acide retinoique pour la preparation d' un medicament destine au traitement de l'obesite.
|
|
AU2893199A
(en)
*
|
1998-03-03 |
1999-09-20 |
Board Of Regents, The University Of Texas System |
Fatty acid-induced beta-cell apoptosis
|
|
AU1707599A
(en)
*
|
1998-03-20 |
1999-10-18 |
Warner-Lambert Company |
Retinoid-glitazone combinations
|
|
US7045519B2
(en)
|
1998-06-19 |
2006-05-16 |
Chiron Corporation |
Inhibitors of glycogen synthase kinase 3
|
|
US6191154B1
(en)
*
|
1998-11-27 |
2001-02-20 |
Case Western Reserve University |
Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
|
|
WO2000035867A1
(en)
*
|
1998-12-14 |
2000-06-22 |
Nuclear Receptor Research Limited |
Novel ligands of nuclear receptor
|
|
US6756360B1
(en)
|
1998-12-24 |
2004-06-29 |
Metabasis Therapeutics, Inc. |
Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes
|
|
US6436993B1
(en)
|
1999-07-13 |
2002-08-20 |
The Salk Institute For Biological Studies |
Use of RAR antagonists as modulators of hormone mediated processes
|
|
DK1206457T3
(da)
*
|
1999-08-27 |
2004-02-16 |
Lilly Co Eli |
Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER
|
|
CA2407421C
(en)
|
2000-04-24 |
2009-11-03 |
Nikken Chemicals Co., Ltd. |
Activators of peroxisome proliferator-activated receptors
|
|
US7563774B2
(en)
|
2000-06-29 |
2009-07-21 |
Metabasis Therapeutics, Inc. |
Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
|
|
US20020031539A1
(en)
*
|
2000-08-30 |
2002-03-14 |
The Brigham And Women's Hospital, Inc. |
Oxidized forms of retinoic acid as ligands for peroxisome proliferator activated receptor gamma
|
|
EP1322152A2
(en)
*
|
2000-10-03 |
2003-07-02 |
ADEREGEM (Association pour le Développement de la Recherche en Génétique Moléculaire |
Transgenic mouse for targeted recombination mediated by modified cre-er
|
|
FR2814642B1
(fr)
|
2000-10-03 |
2005-07-01 |
Ass Pour Le Dev De La Rech En |
Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
|
|
CN100577175C
(zh)
|
2001-04-04 |
2010-01-06 |
奥索-麦克尼尔药品公司 |
包括葡萄糖重吸收抑制剂和ppar调节剂的联合疗法
|
|
CN100384430C
(zh)
*
|
2001-04-04 |
2008-04-30 |
奥索-麦克尼尔药品公司 |
含有葡萄糖重吸收抑制剂和维生素a类-x受体调节剂的联合治疗
|
|
FR2832064A1
(fr)
*
|
2001-11-13 |
2003-05-16 |
Lipha |
Composition pharmaceutique comprenant une glitazone et un derive de thiazolidinedione et son utilisation pour traiter le diabete
|
|
TW200303742A
(en)
*
|
2001-11-21 |
2003-09-16 |
Novartis Ag |
Organic compounds
|
|
US7264813B2
(en)
|
2003-09-24 |
2007-09-04 |
Nikken Sohonsha Corporation |
Therapeutic uses of Dunaliella powder
|
|
CN1921843A
(zh)
*
|
2004-01-23 |
2007-02-28 |
独立行政法人科学技术振兴机构 |
含视黄酸的糖尿病治疗药
|
|
CA2558585C
(en)
|
2004-02-27 |
2010-10-12 |
Amgen Inc. |
Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
|
|
JP4737084B2
(ja)
*
|
2004-03-12 |
2011-07-27 |
堺化学工業株式会社 |
アミド化合物、医薬組成物及びｒｘｒ機能調節剤
|
|
JP5211322B2
(ja)
*
|
2008-03-07 |
2013-06-12 |
国立医薬品食品衛生研究所長 |
ピリミジン−５−カルボン酸誘導体の抗肥満剤としての新規用途
|
|
EP2451455A4
(en)
*
|
2009-07-10 |
2013-01-16 |
Univ Case Western Reserve |
RXR AGONIST COMPOUNDS AND METHODS
|
|
JP5725491B2
(ja)
*
|
2010-04-14 |
2015-05-27 |
国立大学法人鳥取大学 |
レチノイン酸受容体リガンドによるインスリン抵抗性改善作用
|
|
JP6476127B2
(ja)
*
|
2012-11-29 |
2019-02-27 |
タカラ バイオ ヨーロッパ アーベー |
ヒト多能性幹細胞由来肝細胞様細胞の成熟
|
|
CA3114497A1
(en)
|
2013-01-18 |
2014-07-24 |
Cornell University |
Methods of treating diseases associated with high fat diet and vitamin a deficiency using retinoic acid receptor agonists
|
|
EP3116516A4
(en)
*
|
2014-03-13 |
2017-11-15 |
The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone |
Inducing brown fat fate and function
|