JPH09512823A - アデノシン誘導体 - Google Patents

アデノシン誘導体

Info

Publication number
JPH09512823A
JPH09512823A JP7529185A JP52918595A JPH09512823A JP H09512823 A JPH09512823 A JP H09512823A JP 7529185 A JP7529185 A JP 7529185A JP 52918595 A JP52918595 A JP 52918595A JP H09512823 A JPH09512823 A JP H09512823A
Authority
JP
Japan
Prior art keywords
compound
formula
alkyl
trans
methyladenosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7529185A
Other languages
English (en)
Japanese (ja)
Inventor
ガディーント，フルビオ
マンゴールド，ボニー・エル・ケイ
フォザード，ジョン・アール
プラシャド，マハビール
カパ，プラサド・ケイ
Original Assignee
サンド・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9409324A external-priority patent/GB9409324D0/en
Priority claimed from GB9416693A external-priority patent/GB9416693D0/en
Application filed by サンド・リミテッド filed Critical サンド・リミテッド
Publication of JPH09512823A publication Critical patent/JPH09512823A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP7529185A 1994-05-10 1995-05-09 アデノシン誘導体 Pending JPH09512823A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9409324A GB9409324D0 (en) 1994-05-10 1994-05-10 New organic compounds, their preparation and use
GB9409324.2 1994-05-10
US24991494A 1994-05-26 1994-05-26
GB08/249,914 1994-08-18
GB9416693A GB9416693D0 (en) 1994-08-18 1994-08-18 Improvements in or relating to organic compounds
GB9416693.1 1994-08-18
PCT/US1995/005802 WO1995030683A1 (en) 1994-05-10 1995-05-09 Adenosine derivatives

Publications (1)

Publication Number Publication Date
JPH09512823A true JPH09512823A (ja) 1997-12-22

Family

ID=27267177

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7529185A Pending JPH09512823A (ja) 1994-05-10 1995-05-09 アデノシン誘導体

Country Status (13)

Country Link
EP (1) EP0759925A1 (no)
JP (1) JPH09512823A (no)
CN (1) CN1147815A (no)
AU (1) AU2546195A (no)
BR (1) BR9507683A (no)
CA (1) CA2186847A1 (no)
CZ (1) CZ327896A3 (no)
FI (1) FI964468A0 (no)
HU (1) HUT75338A (no)
NO (1) NO964735L (no)
PL (1) PL316985A1 (no)
SK (1) SK146096A3 (no)
WO (1) WO1995030683A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
GB0228723D0 (en) 2002-12-09 2003-01-15 Cambridge Biotechnology Ltd Treatment of pain
GB0305149D0 (en) * 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Compounds for the treatment of pain
EP2021350B1 (en) 2006-03-21 2016-12-21 Rheinische Friedrich-Wilhelms-Universität Bonn Phosphorylated a2a receptor agonists
CN108822174A (zh) * 2018-08-29 2018-11-16 上海兆维科技发展有限公司 新型核苷修饰物2’-eoe-鸟嘌呤核苷及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729994D0 (en) * 1987-12-23 1988-02-03 Glaxo Group Ltd Chemical compounds
GB2226027B (en) * 1988-12-13 1992-05-20 Sandoz Ltd Adenosine derivatives,their production and use
US5017578A (en) * 1989-06-09 1991-05-21 Hoechst-Roussel Pharmaceuticals Inc. N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents
HUT61567A (en) * 1990-12-07 1993-01-28 Sandoz Ag Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate
DK62692D0 (no) * 1992-05-14 1992-05-14 Novo Nordisk As

Also Published As

Publication number Publication date
CZ327896A3 (en) 1997-03-12
NO964735L (no) 1997-01-10
AU2546195A (en) 1995-11-29
EP0759925A1 (en) 1997-03-05
HUT75338A (en) 1997-05-28
FI964468A (fi) 1996-11-06
FI964468A0 (fi) 1996-11-06
CA2186847A1 (en) 1995-11-16
BR9507683A (pt) 1997-09-23
NO964735D0 (no) 1996-11-08
HU9603105D0 (en) 1997-01-28
PL316985A1 (en) 1997-03-03
SK146096A3 (en) 1997-07-09
WO1995030683A1 (en) 1995-11-16
CN1147815A (zh) 1997-04-16

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