JPH09500878A - 治療活性を有するベンゾキサジノン及びベンゾチアジノン - Google Patents

治療活性を有するベンゾキサジノン及びベンゾチアジノン

Info

Publication number
JPH09500878A
JPH09500878A JP7505529A JP50552995A JPH09500878A JP H09500878 A JPH09500878 A JP H09500878A JP 7505529 A JP7505529 A JP 7505529A JP 50552995 A JP50552995 A JP 50552995A JP H09500878 A JPH09500878 A JP H09500878A
Authority
JP
Japan
Prior art keywords
mol
compound
alkyl
dihydro
nmr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7505529A
Other languages
English (en)
Japanese (ja)
Inventor
レヴィ，シルヴィーオ
ベネディーニ，フランチェスカ
ベルトリーニ，ジョルジオ
グローモ，ジャンニ
ミズライ，ザーク
サラ，アルベルト
Original Assignee
イタルファルマコ・ソシエタ・ペル・アチオニ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イタルファルマコ・ソシエタ・ペル・アチオニ filed Critical イタルファルマコ・ソシエタ・ペル・アチオニ
Publication of JPH09500878A publication Critical patent/JPH09500878A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP7505529A 1993-07-28 1994-07-18 治療活性を有するベンゾキサジノン及びベンゾチアジノン Pending JPH09500878A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT93MI001678A IT1264812B1 (it) 1993-07-28 1993-07-28 Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi
IT93A001678 1993-07-28
PCT/EP1994/002354 WO1995004048A1 (en) 1993-07-28 1994-07-18 Benzoxazinones and benzothiazinones endowed with therapeutic activity

Publications (1)

Publication Number Publication Date
JPH09500878A true JPH09500878A (ja) 1997-01-28

Family

ID=11366700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7505529A Pending JPH09500878A (ja) 1993-07-28 1994-07-18 治療活性を有するベンゾキサジノン及びベンゾチアジノン

Country Status (13)

Country Link
EP (1) EP0711286A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH09500878A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1128025A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU7494594A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2168099A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI960342A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUT74587A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL110473A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1264812B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO960308L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW277061B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1995004048A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA945555B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
CN102367239B (zh) * 2011-07-20 2015-10-28 沈阳药科大学 2-芳基-2,3-二氢-4h-1,3-苯并噻嗪-4-酮衍生物及其用途
JP6132915B2 (ja) * 2012-08-27 2017-05-24 ユニバーシティ オブ テネシー リサーチ ファウンデーション Ｌｐａ２受容体特異的安息香酸誘導体
ITMI20122221A1 (it) 2012-12-21 2014-06-22 C4T S C A R L Nuovi composti del 2,3-diidro-4h-1,3-benzossazin-4-one, metodo per prepararli e forma farmaceutica che li comprende
EA029415B1 (ru) * 2013-12-19 2018-03-30 Джилид Сайэнс, Инк. Производные 2-оксо-3,4-дигидро-2н-бензо[e][1,3]оксазина

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2443M (fr) * 1962-10-30 1964-04-06 Selvi & C Lab Bioterapico Thio-dérivés de benzo-oxazine ayant des propriétés antiphlogistiques, antipyrétiques et analgésiques.
US3459748A (en) * 1967-04-28 1969-08-05 Squibb & Sons Inc Hydroxyalkylene-substituted benzoxazines and benzothiazines
IT1136575B (it) * 1981-04-15 1986-09-03 Coli Farma Lab Esteri del 2-(2-ossietil)-2,3-diidro-h4-1,3-benzossazin-4-one ad attivita' analgesica e procedimento per la loro preparazione
IT1244472B (it) * 1990-12-14 1994-07-15 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare
FR2680172B1 (fr) * 1991-08-05 1993-11-19 Fabre Medicament Pierre Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
IT1254884B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare

Also Published As

Publication number Publication date
CA2168099A1 (en) 1995-02-09
ITMI931678A0 (it) 1993-07-28
NO960308D0 (no) 1996-01-25
EP0711286A1 (en) 1996-05-15
HU9600165D0 (en) 1996-03-28
FI960342L (fi) 1996-01-25
HUT74587A (en) 1997-01-28
FI960342A0 (fi) 1996-01-25
WO1995004048A1 (en) 1995-02-09
FI960342A7 (fi) 1996-01-25
IT1264812B1 (it) 1996-10-10
ZA945555B (en) 1995-03-03
ITMI931678A1 (it) 1995-01-28
CN1128025A (zh) 1996-07-31
NO960308L (no) 1996-03-13
TW277061B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1996-06-01
IL110473A0 (en) 1994-10-21
AU7494594A (en) 1995-02-28

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