ZA945555B - Benzoxazinones and benzothiazinones with therapeutic activity - Google Patents

Benzoxazinones and benzothiazinones with therapeutic activity

Info

Publication number
ZA945555B
ZA945555B ZA945555A ZA945555A ZA945555B ZA 945555 B ZA945555 B ZA 945555B ZA 945555 A ZA945555 A ZA 945555A ZA 945555 A ZA945555 A ZA 945555A ZA 945555 B ZA945555 B ZA 945555B
Authority
ZA
South Africa
Prior art keywords
benzothiazinones
benzoxazinones
therapeutic activity
therapeutic
activity
Prior art date
Application number
ZA945555A
Inventor
Silvio Levi
Francesca Benedini
Giorgio Bertolini
Gianni Gromo
Jacques Mizrhai
Alberto Sala
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of ZA945555B publication Critical patent/ZA945555B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA945555A 1993-07-28 1994-07-27 Benzoxazinones and benzothiazinones with therapeutic activity ZA945555B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001678A IT1264812B1 (en) 1993-07-28 1993-07-28 THERAPEUTICALLY ACTIVE BENZOSSAZINONIC AND BENZOTHIAZINONIC DERIVATIVES

Publications (1)

Publication Number Publication Date
ZA945555B true ZA945555B (en) 1995-03-03

Family

ID=11366700

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA945555A ZA945555B (en) 1993-07-28 1994-07-27 Benzoxazinones and benzothiazinones with therapeutic activity

Country Status (13)

Country Link
EP (1) EP0711286A1 (en)
JP (1) JPH09500878A (en)
CN (1) CN1128025A (en)
AU (1) AU7494594A (en)
CA (1) CA2168099A1 (en)
FI (1) FI960342A (en)
HU (1) HUT74587A (en)
IL (1) IL110473A0 (en)
IT (1) IT1264812B1 (en)
NO (1) NO960308L (en)
TW (1) TW277061B (en)
WO (1) WO1995004048A1 (en)
ZA (1) ZA945555B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102367239B (en) * 2011-07-20 2015-10-28 沈阳药科大学 2-aryl-2,3-dihydro-4H-1,3-benzothiazine-4-ketone derivatives and uses thereof
AU2013308963A1 (en) * 2012-08-27 2015-03-19 University Of Tennessee Research Foundation LPA2 receptor-specific benzoic acid derivatives
ITMI20122221A1 (en) * 2012-12-21 2014-06-22 C4T S C A R L NEW COMPOUNDS OF 2,3-DIIDRO-4H-1,3-BENZOSSAZIN-4-ONE, METHOD FOR PREPARING THEM AND PHARMACEUTICAL FORM THAT INCLUDES THEM
SG11201604457XA (en) * 2013-12-19 2016-07-28 Gilead Sciences Inc Fused heterocyclic compounds as ion channel modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2443M (en) * 1962-10-30 1964-04-06 Selvi & C Lab Bioterapico Thio-derivatives of benzo-oxazine having antiphlogistic, antipyretic and analgesic properties.
US3459748A (en) * 1967-04-28 1969-08-05 Squibb & Sons Inc Hydroxyalkylene-substituted benzoxazines and benzothiazines
IT1136575B (en) * 1981-04-15 1986-09-03 Coli Farma Lab ESTERS OF 2- (2-OSSIETIL) -2,3-DIIDRO-H4-1,3-BENZOSSAZIN-4-ONE WITH ANALGESIC ACTIVITY AND PROCEDURE FOR THEIR PREPARATION
IT1244472B (en) * 1990-12-14 1994-07-15 Italfarmaco Spa BENZOSSAZINONI AND BENZOTIAZINONI WITH CARDIOVASCULAR ACTIVITY
FR2680172B1 (en) * 1991-08-05 1993-11-19 Fabre Medicament Pierre NEW SUBSTITUTED PIPERAZINYLALCOYL-3 DIHYDRO-2,3 4H-BENZOXAZINE-1,3 ONES-4, THEIR PREPARATION AND THERAPEUTIC APPLICATION.
IT1254884B (en) * 1992-04-16 1995-10-11 Italfarmaco Spa BENZOSSAZINONI AND BENZOTIAZINONI WITH CARDIOVASCULAR ACTIVITY

Also Published As

Publication number Publication date
WO1995004048A1 (en) 1995-02-09
TW277061B (en) 1996-06-01
CN1128025A (en) 1996-07-31
FI960342A0 (en) 1996-01-25
CA2168099A1 (en) 1995-02-09
NO960308D0 (en) 1996-01-25
EP0711286A1 (en) 1996-05-15
AU7494594A (en) 1995-02-28
HUT74587A (en) 1997-01-28
HU9600165D0 (en) 1996-03-28
FI960342A (en) 1996-01-25
IT1264812B1 (en) 1996-10-10
ITMI931678A0 (en) 1993-07-28
NO960308L (en) 1996-03-13
JPH09500878A (en) 1997-01-28
IL110473A0 (en) 1994-10-21
ITMI931678A1 (en) 1995-01-28

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