IL106037A0 - Therapeutic and diagnostic methods based on neurotrophin-4-expression - Google Patents

Therapeutic and diagnostic methods based on neurotrophin-4-expression

Info

Publication number
IL106037A0
IL106037A0 IL10603793A IL10603793A IL106037A0 IL 106037 A0 IL106037 A0 IL 106037A0 IL 10603793 A IL10603793 A IL 10603793A IL 10603793 A IL10603793 A IL 10603793A IL 106037 A0 IL106037 A0 IL 106037A0
Authority
IL
Israel
Prior art keywords
neurotrophin
therapeutic
expression
methods based
diagnostic methods
Prior art date
Application number
IL10603793A
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of IL106037A0 publication Critical patent/IL106037A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
IL10603793A 1992-06-12 1993-06-15 Therapeutic and diagnostic methods based on neurotrophin-4-expression IL106037A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89819492A 1992-06-12 1992-06-12

Publications (1)

Publication Number Publication Date
IL106037A0 true IL106037A0 (en) 1994-08-26

Family

ID=25409081

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10603793A IL106037A0 (en) 1992-06-12 1993-06-15 Therapeutic and diagnostic methods based on neurotrophin-4-expression

Country Status (6)

Country Link
EP (1) EP0644937A4 (en)
JP (1) JPH07509600A (en)
AU (1) AU4535993A (en)
CA (1) CA2137799A1 (en)
IL (1) IL106037A0 (en)
WO (1) WO1993025684A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566091B1 (en) 1990-09-25 2003-05-20 Genentech, Inc. Neurotrophic factor
US6506728B2 (en) 1990-09-25 2003-01-14 Genentech, Inc. Methods using a novel neurotrophic factor, NT-4
WO1992005254A1 (en) * 1990-09-25 1992-04-02 Genentech, Inc. Novel neurothrophic factor
US5470719A (en) * 1994-03-18 1995-11-28 Meng; Shi-Yuan Modified OmpA signal sequence for enhanced secretion of polypeptides
EP0753013A1 (en) * 1994-03-29 1997-01-15 Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. Neurotrophin-6: a new member of the neurotrophin family
US7144983B1 (en) 1997-02-03 2006-12-05 Genentech, Inc. Pantropic neurotrophic factors
US5728803A (en) 1994-06-03 1998-03-17 Genentech, Inc. Pantropic neurotrophic factors
US5556837A (en) * 1994-08-01 1996-09-17 Regeneron Pharmaceuticals Inc. Methods for treating addictive disorders
CN1233963A (en) 1996-09-13 1999-11-03 有限会社最先端医学研究所 Ophthalmic compositions of neurotrophic factor, remedies for optic nerve function disorders and method for treating same
KR20000070357A (en) 1997-01-23 2000-11-25 다께우찌 마사야쓰 Remedies for diabetes
US6331523B1 (en) 1998-03-12 2001-12-18 Genentech, Inc. Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5
WO2000007613A1 (en) * 1998-08-05 2000-02-17 Advanced Medicine Research Institute Remedies for cerebral central lesions with the use of neurotrophic factors
WO2003011395A2 (en) * 2001-07-31 2003-02-13 University Of Medicine & Dentistry Of New Jersey Method of utilizing neurotrophins to manipulate reproductive capacity
CN101360759A (en) 2005-11-07 2009-02-04 哥本哈根大学 Neurotrophin-derived peptide sequences
WO2008078179A1 (en) * 2006-12-20 2008-07-03 Rinat Neuroscience Corporation Trkb agonists for treating autoimmune disorders
CN111000984A (en) * 2019-11-16 2020-04-14 祁展楷 Application of snake nerve growth factor and snake nerve growth factor precursor in treating senile dementia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL95511A (en) * 1989-08-30 2000-10-31 Max Planck Gesellschaft Neurotrophin-3 a novel neurotrophic factor related to nerve growth and brain derived neurotrophic factor
WO1992005254A1 (en) * 1990-09-25 1992-04-02 Genentech, Inc. Novel neurothrophic factor
IL101661A (en) * 1991-04-23 1998-02-08 Regeneron Pharma Method for detecting, identifying or measuring agents having neurotrophin activity
WO1992020797A1 (en) * 1991-05-20 1992-11-26 Case Western Reserve University Neurotrophic factor, preparation and uses thereof
CA2109598A1 (en) * 1991-05-21 1992-11-26 Finn Hallbook Therapeutic and diagnostic methods based on neurotrophin-4- expression
ATE202939T1 (en) * 1991-07-10 2001-07-15 Regeneron Pharma METHOD FOR TREATING MOTOR NEURON DISEASES BY MEMBERS OF THE BDNF/NT-3/NGF FAMILY

Also Published As

Publication number Publication date
EP0644937A1 (en) 1995-03-29
AU4535993A (en) 1994-01-04
JPH07509600A (en) 1995-10-26
WO1993025684A1 (en) 1993-12-23
CA2137799A1 (en) 1993-12-23
EP0644937A4 (en) 1995-05-03

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