JPH09500539A - 核酸のリンクされた線形増幅 - Google Patents

核酸のリンクされた線形増幅

Info

Publication number
JPH09500539A
JPH09500539A JP7505384A JP50538495A JPH09500539A JP H09500539 A JPH09500539 A JP H09500539A JP 7505384 A JP7505384 A JP 7505384A JP 50538495 A JP50538495 A JP 50538495A JP H09500539 A JPH09500539 A JP H09500539A
Authority
JP
Japan
Prior art keywords
primer
nucleic acid
generation
template
primer extension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7505384A
Other languages
English (en)
Japanese (ja)
Inventor
ウォーレス，ロバート・ブルース
Original Assignee
バイオ−ラッド・ラボラトリーズ・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオ−ラッド・ラボラトリーズ・インコーポレーテッド filed Critical バイオ−ラッド・ラボラトリーズ・インコーポレーテッド
Publication of JPH09500539A publication Critical patent/JPH09500539A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP7505384A 1993-07-23 1994-07-25 核酸のリンクされた線形増幅 Pending JPH09500539A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9544293A 1993-07-23 1993-07-23
US08/095,442 1993-07-23
PCT/US1994/008390 WO1995003432A1 (fr) 1993-07-23 1994-07-25 Amplification lineaire enchainee d'acides nucleiques

Publications (1)

Publication Number Publication Date
JPH09500539A true JPH09500539A (ja) 1997-01-21

Family

ID=22252059

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7505384A Pending JPH09500539A (ja) 1993-07-23 1994-07-25 核酸のリンクされた線形増幅

Country Status (5)

Country Link
EP (1) EP0710296A4 (fr)
JP (1) JPH09500539A (fr)
CN (1) CN1127533A (fr)
CA (1) CA2167840A1 (fr)
WO (1) WO1995003432A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016529914A (ja) * 2013-09-13 2016-09-29 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ポリＡ−キャリヤーにより誘導される高分子量ＰＣＲ生成物の生成を避けるためのオリゴ−ｄＴ分子の適用

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335184B1 (en) 1993-07-23 2002-01-01 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
JPH11507235A (ja) * 1995-06-07 1999-06-29 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド 核酸の連結型線形増幅法
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
DK0862656T3 (da) 1995-11-21 2001-04-09 Univ Yale Unimolekylær segmentamplifikation og -detektering
US6316229B1 (en) 1998-07-20 2001-11-13 Yale University Single molecule analysis target-mediated ligation of bipartite primers
CA2342838A1 (fr) 1998-09-15 2000-03-23 Yale University Clonage moleculaire a amplification selon le modele du cercle roulant
JP2002525078A (ja) 1998-09-15 2002-08-13 イェール ユニバーシティ 人工的長末端反復配列
US7205129B1 (en) * 2000-02-28 2007-04-17 Qiagen Gmbh Method for reducing artifacts in nucleic acid amplification
DE60130763T2 (de) 2000-06-30 2008-07-17 Qiagen Gmbh Signalamplifikation mit "lollipop"-hydridisierungsproben
US6573051B2 (en) 2001-03-09 2003-06-03 Molecular Staging, Inc. Open circle probes with intramolecular stem structures
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
EP1762627A1 (fr) 2005-09-09 2007-03-14 Qiagen GmbH Procédé pour l'activation d'acides nucléiques pour effectuer une réaction d'une polymérase
EP2377929A1 (fr) 2005-10-06 2011-10-19 Lucigen Corporation Polymérases virales thermostables et procédés d'utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
GB8920097D0 (en) * 1989-09-06 1989-10-18 Ici Plc Amplification processes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016529914A (ja) * 2013-09-13 2016-09-29 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ポリＡ−キャリヤーにより誘導される高分子量ＰＣＲ生成物の生成を避けるためのオリゴ−ｄＴ分子の適用

Also Published As

Publication number Publication date
CN1127533A (zh) 1996-07-24
CA2167840A1 (fr) 1995-02-02
WO1995003432A1 (fr) 1995-02-02
EP0710296A1 (fr) 1996-05-08
EP0710296A4 (fr) 1999-05-26

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