JPH08507774A - 手術後の悪心および嘔吐の治療のためのグラニセトロンの使用 - Google Patents
手術後の悪心および嘔吐の治療のためのグラニセトロンの使用Info
- Publication number
- JPH08507774A JPH08507774A JP6520641A JP52064194A JPH08507774A JP H08507774 A JPH08507774 A JP H08507774A JP 6520641 A JP6520641 A JP 6520641A JP 52064194 A JP52064194 A JP 52064194A JP H08507774 A JPH08507774 A JP H08507774A
- Authority
- JP
- Japan
- Prior art keywords
- granisetron
- vomiting
- placebo
- ponv
- nausea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.手術後の悪心および嘔吐(PONV)治療用医薬の製造におけるグラニセ トロン(granisetron)の使用。 2.治療を必要とする哺乳動物にグラニセトロンを投与することによる、ヒト を含む哺乳動物におけるPONVの治療方法。 3.グラニセトロンおよび医薬上許容される担体からなるPONV治療用医薬 組成物。 4.医薬が静脈内投与による投与に適合したものである請求項1、2または3 記載の使用、方法または組成物。 5.グラニセトロンが1mgないし3mgの剤型で投与される請求項1、2、 3または4記載の使用、方法または組成物。 6.グラニセトロンが、手術前、手術中または手術後に投与される請求項1、 2、3、4または5記載の使用、方法または組成物。 7.グラニセトロンが手術前に投与される請求項1、2、3、4または5記載 の使用、方法または組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939305593A GB9305593D0 (en) | 1993-03-18 | 1993-03-18 | Pharmaceuticals |
GB9305593.7 | 1993-03-18 | ||
PCT/EP1994/000820 WO1994021257A1 (en) | 1993-03-18 | 1994-03-15 | Use of granisetron for the treatment of post-operative nausea and vomiting |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005359022A Division JP2006083190A (ja) | 1993-03-18 | 2005-12-13 | 手術後の悪心および嘔吐の治療のためのグラニセトロンの使用 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH08507774A true JPH08507774A (ja) | 1996-08-20 |
JP3792251B2 JP3792251B2 (ja) | 2006-07-05 |
Family
ID=10732290
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52064194A Expired - Lifetime JP3792251B2 (ja) | 1993-03-18 | 1994-03-15 | 手術後の悪心および嘔吐の治療のためのグラニセトロンの使用 |
JP2005359022A Pending JP2006083190A (ja) | 1993-03-18 | 2005-12-13 | 手術後の悪心および嘔吐の治療のためのグラニセトロンの使用 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005359022A Pending JP2006083190A (ja) | 1993-03-18 | 2005-12-13 | 手術後の悪心および嘔吐の治療のためのグラニセトロンの使用 |
Country Status (21)
Country | Link |
---|---|
US (1) | US5952340A (ja) |
EP (1) | EP0689437B1 (ja) |
JP (2) | JP3792251B2 (ja) |
KR (1) | KR100315606B1 (ja) |
CN (1) | CN1085079C (ja) |
AP (1) | AP511A (ja) |
AT (1) | ATE230596T1 (ja) |
AU (1) | AU676032B2 (ja) |
CA (1) | CA2158354C (ja) |
CY (1) | CY2427B1 (ja) |
DE (1) | DE69431986T2 (ja) |
DK (1) | DK0689437T3 (ja) |
ES (1) | ES2188611T3 (ja) |
GB (1) | GB9305593D0 (ja) |
HK (1) | HK1012237A1 (ja) |
HU (1) | HU214629B (ja) |
IL (1) | IL109059A (ja) |
SG (1) | SG46724A1 (ja) |
TW (1) | TW312622B (ja) |
WO (1) | WO1994021257A1 (ja) |
ZA (1) | ZA941844B (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014034571A (ja) * | 2012-08-10 | 2014-02-24 | Terumo Corp | 安定なグラニセトロン含有水性製剤 |
JP2017077484A (ja) * | 2016-11-30 | 2017-04-27 | テルモ株式会社 | 安定なグラニセトロン含有水性製剤の包装体 |
JP2019533700A (ja) * | 2016-11-01 | 2019-11-21 | アカシア ファーマ リミテッドAcacia Pharma Limited | アミスルプリドによる術後嘔吐の治療法 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9412995D0 (en) * | 1994-06-28 | 1994-10-26 | Prendergast Kenneth F | Safety enhancing pharmaceutical compositions of an active indazole |
AU2003237657A1 (en) * | 2002-05-24 | 2003-12-12 | Epidauros Biotechnologie Ag | Means and methods for improved treatment using "setrones" |
SE0203410D0 (sv) * | 2002-11-18 | 2002-11-18 | Astrazeneca Ab | New use |
JO2735B1 (en) * | 2003-01-30 | 2013-09-15 | هيلسين هيلث كير أس ايه. | Liquid pharmaceutical formations of balloonosterone |
MY143789A (en) | 2003-02-18 | 2011-07-15 | Helsinn Healthcare Sa | Use of palonosetron treating post- operative nausea and vomiting |
GB0328186D0 (en) * | 2003-12-05 | 2004-01-07 | West Pharm Serv Drug Res Ltd | Intranasal compositions |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8525913D0 (en) * | 1985-10-21 | 1985-11-27 | Beecham Group Plc | Compounds |
EP0200444B1 (en) * | 1985-04-27 | 1992-11-11 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-ht antagonist activity |
GB8928837D0 (en) * | 1989-12-21 | 1990-02-28 | Beecham Group Plc | Pharmaceuticals |
US5225407A (en) * | 1990-02-22 | 1993-07-06 | Glaxo Group Limited | 5-HT3 receptor antagonists for the treatment of autism |
ES2149767T5 (es) * | 1991-09-20 | 2005-06-16 | Glaxo Group Limited | Nuevo uso medico para antagonistas de taquiquininas. |
-
1993
- 1993-03-18 GB GB939305593A patent/GB9305593D0/en active Pending
-
1994
- 1994-03-15 HU HU9502692A patent/HU214629B/hu unknown
- 1994-03-15 JP JP52064194A patent/JP3792251B2/ja not_active Expired - Lifetime
- 1994-03-15 SG SG1996009426A patent/SG46724A1/en unknown
- 1994-03-15 US US08/525,521 patent/US5952340A/en not_active Expired - Lifetime
- 1994-03-15 DK DK94911178T patent/DK0689437T3/da active
- 1994-03-15 EP EP94911178A patent/EP0689437B1/en not_active Revoked
- 1994-03-15 CA CA002158354A patent/CA2158354C/en not_active Expired - Lifetime
- 1994-03-15 ES ES94911178T patent/ES2188611T3/es not_active Expired - Lifetime
- 1994-03-15 DE DE69431986T patent/DE69431986T2/de not_active Revoked
- 1994-03-15 WO PCT/EP1994/000820 patent/WO1994021257A1/en active IP Right Grant
- 1994-03-15 AU AU63774/94A patent/AU676032B2/en not_active Expired
- 1994-03-15 AT AT94911178T patent/ATE230596T1/de not_active IP Right Cessation
- 1994-03-15 KR KR1019950703945A patent/KR100315606B1/ko not_active IP Right Cessation
- 1994-03-16 ZA ZA941844A patent/ZA941844B/xx unknown
- 1994-03-16 AP APAP/P/1994/000626A patent/AP511A/en active
- 1994-03-21 IL IL10905994A patent/IL109059A/en not_active IP Right Cessation
- 1994-04-06 TW TW083102963A patent/TW312622B/zh not_active IP Right Cessation
- 1994-09-29 CN CN94192028A patent/CN1085079C/zh not_active Expired - Lifetime
-
1998
- 1998-12-15 HK HK98113470A patent/HK1012237A1/xx not_active IP Right Cessation
-
2004
- 2004-02-25 CY CY0400013A patent/CY2427B1/xx unknown
-
2005
- 2005-12-13 JP JP2005359022A patent/JP2006083190A/ja active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014034571A (ja) * | 2012-08-10 | 2014-02-24 | Terumo Corp | 安定なグラニセトロン含有水性製剤 |
JP2019533700A (ja) * | 2016-11-01 | 2019-11-21 | アカシア ファーマ リミテッドAcacia Pharma Limited | アミスルプリドによる術後嘔吐の治療法 |
JP2017077484A (ja) * | 2016-11-30 | 2017-04-27 | テルモ株式会社 | 安定なグラニセトロン含有水性製剤の包装体 |
Also Published As
Publication number | Publication date |
---|---|
TW312622B (ja) | 1997-08-11 |
DK0689437T3 (da) | 2003-04-28 |
JP3792251B2 (ja) | 2006-07-05 |
CN1085079C (zh) | 2002-05-22 |
AP511A (en) | 1996-07-26 |
AP9400626A0 (en) | 1994-04-30 |
HK1012237A1 (en) | 1999-07-30 |
HUT73502A (en) | 1996-08-28 |
US5952340A (en) | 1999-09-14 |
CA2158354C (en) | 2004-07-13 |
AU6377494A (en) | 1994-10-11 |
EP0689437B1 (en) | 2003-01-08 |
ATE230596T1 (de) | 2003-01-15 |
WO1994021257A1 (en) | 1994-09-29 |
CY2427B1 (en) | 2004-11-12 |
ES2188611T3 (es) | 2003-07-01 |
AU676032B2 (en) | 1997-02-27 |
DE69431986D1 (de) | 2003-02-13 |
SG46724A1 (en) | 1998-02-20 |
IL109059A0 (en) | 1994-11-28 |
GB9305593D0 (en) | 1993-05-05 |
EP0689437A1 (en) | 1996-01-03 |
HU9502692D0 (en) | 1995-11-28 |
KR100315606B1 (ko) | 2002-04-24 |
CA2158354A1 (en) | 1994-09-29 |
CN1122570A (zh) | 1996-05-15 |
IL109059A (en) | 1996-11-14 |
HU214629B (hu) | 1998-04-28 |
JP2006083190A (ja) | 2006-03-30 |
DE69431986T2 (de) | 2003-11-06 |
ZA941844B (en) | 1995-09-18 |
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