JPH07501818A - 結腸直腸癌の治療 - Google Patents

結腸直腸癌の治療

Info

Publication number
JPH07501818A
JPH07501818A JP5510863A JP51086393A JPH07501818A JP H07501818 A JPH07501818 A JP H07501818A JP 5510863 A JP5510863 A JP 5510863A JP 51086393 A JP51086393 A JP 51086393A JP H07501818 A JPH07501818 A JP H07501818A
Authority
JP
Japan
Prior art keywords
days
hydroxy
colorectal cancer
per day
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5510863A
Other languages
English (en)
Japanese (ja)
Inventor
ジョンソン，ランドール・キース
Original Assignee
スミスクライン・ビーチャム・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スミスクライン・ビーチャム・コーポレイション filed Critical スミスクライン・ビーチャム・コーポレイション
Publication of JPH07501818A publication Critical patent/JPH07501818A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
JP5510863A 1991-12-10 1992-07-24 結腸直腸癌の治療 Pending JPH07501818A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80457091A 1991-12-10 1991-12-10
US804,570 1991-12-10
PCT/US1992/006131 WO1993011770A1 (en) 1991-12-10 1992-07-24 Treatment of colorectal cancer

Publications (1)

Publication Number Publication Date
JPH07501818A true JPH07501818A (ja) 1995-02-23

Family

ID=25189304

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5510863A Pending JPH07501818A (ja) 1991-12-10 1992-07-24 結腸直腸癌の治療

Country Status (7)

Country Link
EP (1) EP0661977A1 (es)
JP (1) JPH07501818A (es)
AU (1) AU2394392A (es)
CA (1) CA2125293A1 (es)
MX (1) MX9205766A (es)
PT (1) PT100948A (es)
WO (1) WO1993011770A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003508400A (ja) * 1999-09-01 2003-03-04 ギルフォード ファーマシューティカルズ インコーポレイテッド 神経または心臓血管の組織損傷等の、細胞損傷を治療するための化合物、方法、及び製薬組成物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552154A (en) 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
DE69409633T2 (de) * 1993-01-15 1998-08-06 The Stehlin Foundation For Cancer Research, Houston, Tex. Transdermal behandlung von krebs mit wasserunlöslichem s-camtothecin mit geschlossenem lactoring
ES2371171B1 (es) * 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN102477042A (zh) * 2010-11-26 2012-05-30 复旦大学 10-羟基喜树碱衍生物及其制备方法和用途
CN102659800B (zh) * 2012-05-11 2014-09-03 中国药科大学 一类低氧激活抗肿瘤化合物及其用途
CN103113381B (zh) * 2013-02-26 2014-12-10 大连理工大学 系列水溶性羟基喜树碱环烷胺醇衍生物及其制法与用途
WO2021173773A1 (en) 2020-02-25 2021-09-02 Mediboston, Inc. Camptothecin derivatives and conjugates thereof
CN117599058A (zh) * 2023-03-09 2024-02-27 兰州大学 喜树碱类衍生物在制备治疗膀胱癌药物中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01209120A (ja) * 1988-02-17 1989-08-22 Sekisui Plastics Co Ltd スチレン系樹脂発泡シートの製造方法
JPH02160842A (ja) * 1988-12-15 1990-06-20 Toyo Eng Corp 発泡体の製造方法
JPH04198238A (ja) * 1990-11-27 1992-07-17 Matsushita Electric Works Ltd 疎水性エアロゲルの製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01209120A (ja) * 1988-02-17 1989-08-22 Sekisui Plastics Co Ltd スチレン系樹脂発泡シートの製造方法
JPH02160842A (ja) * 1988-12-15 1990-06-20 Toyo Eng Corp 発泡体の製造方法
JPH04198238A (ja) * 1990-11-27 1992-07-17 Matsushita Electric Works Ltd 疎水性エアロゲルの製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003508400A (ja) * 1999-09-01 2003-03-04 ギルフォード ファーマシューティカルズ インコーポレイテッド 神経または心臓血管の組織損傷等の、細胞損傷を治療するための化合物、方法、及び製薬組成物

Also Published As

Publication number Publication date
EP0661977A4 (en) 1994-10-20
PT100948A (pt) 1994-01-31
WO1993011770A1 (en) 1993-06-24
MX9205766A (es) 1993-06-01
CA2125293A1 (en) 1993-06-24
EP0661977A1 (en) 1995-07-12
AU2394392A (en) 1993-07-19

Similar Documents

Publication Publication Date Title
EP0612248B1 (en) Composition containing cisplatin and topotecan as antitumor agent.
JP2001247459A (ja) 癌の組み合わせ療法
KR20030060771A (ko) 국소용 마취제/아편양약물 제제 및 이들의 용도
JP2003514013A (ja) 医薬組成物
JP2003515559A (ja) ゾルミトリプタン含有医薬製剤
KR20130073948A (ko) 암 치료를 위한 새로운 병용 요법
US20040266809A1 (en) Method of treating multiple myeloma
JPH07501818A (ja) 結腸直腸癌の治療
US5674872A (en) Treatment of ovarian cancer
JP3470901B2 (ja) Ｅｌｆ５Ａ生合成の抑制方法
AU664172B2 (en) Treatment of esophageal cancer
US5756512A (en) Treatment of non-small cell lung carcinoma
JP2778632B2 (ja) 卵巣癌の治療用医薬組成物
JP2001526217A (ja) 血管性頭痛に対する局所麻酔薬の新規な使用
KR20120104574A (ko) 티보자닙과 템시롤리무스의 조합물
Leahy et al. Treatment of advanced malignant melanoma with high dose methotrexate and folinic acid rescue
AU2002366975B2 (en) Quinazolinone compounds in combined modalities for improved cancer treatment
RU2164094C1 (ru) Способ лечения местно-распространенного рака полости рта