AU2394392A - Treatment of colorectal cancer - Google Patents

Treatment of colorectal cancer

Info

Publication number
AU2394392A
AU2394392A AU23943/92A AU2394392A AU2394392A AU 2394392 A AU2394392 A AU 2394392A AU 23943/92 A AU23943/92 A AU 23943/92A AU 2394392 A AU2394392 A AU 2394392A AU 2394392 A AU2394392 A AU 2394392A
Authority
AU
Australia
Prior art keywords
course
therapy
hydroxy
day
topotecan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU23943/92A
Other languages
English (en)
Inventor
Randall Keith Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU2394392A publication Critical patent/AU2394392A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
AU23943/92A 1991-12-10 1992-07-24 Treatment of colorectal cancer Abandoned AU2394392A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80457091A 1991-12-10 1991-12-10
US804570 1991-12-10

Publications (1)

Publication Number Publication Date
AU2394392A true AU2394392A (en) 1993-07-19

Family

ID=25189304

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23943/92A Abandoned AU2394392A (en) 1991-12-10 1992-07-24 Treatment of colorectal cancer

Country Status (7)

Country Link
EP (1) EP0661977A1 (es)
JP (1) JPH07501818A (es)
AU (1) AU2394392A (es)
CA (1) CA2125293A1 (es)
MX (1) MX9205766A (es)
PT (1) PT100948A (es)
WO (1) WO1993011770A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552154A (en) 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
ES2114681T3 (es) * 1993-01-15 1998-06-01 Stehlin Foundation For Cancer Tratamiento transdermico de cancer con camptotecina insoluble en agua en la forma de anillo de lactona cerrado.
US6291425B1 (en) * 1999-09-01 2001-09-18 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
ES2371171B1 (es) * 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN102477042A (zh) * 2010-11-26 2012-05-30 复旦大学 10-羟基喜树碱衍生物及其制备方法和用途
CN102659800B (zh) * 2012-05-11 2014-09-03 中国药科大学 一类低氧激活抗肿瘤化合物及其用途
CN103113381B (zh) * 2013-02-26 2014-12-10 大连理工大学 系列水溶性羟基喜树碱环烷胺醇衍生物及其制法与用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
JPH0641161B2 (ja) * 1988-02-17 1994-06-01 積水化成品工業株式会社 スチレン系樹脂発泡シートの製造方法及び加熱成形用スチレン系樹脂発泡シート
JPH0768403B2 (ja) * 1988-12-15 1995-07-26 東洋エンジニアリング株式会社 発泡体の製造方法
JP2756366B2 (ja) * 1990-11-27 1998-05-25 松下電工株式会社 疎水性エアロゲルの製造方法

Also Published As

Publication number Publication date
MX9205766A (es) 1993-06-01
JPH07501818A (ja) 1995-02-23
EP0661977A4 (en) 1994-10-20
CA2125293A1 (en) 1993-06-24
PT100948A (pt) 1994-01-31
EP0661977A1 (en) 1995-07-12
WO1993011770A1 (en) 1993-06-24

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