JPH0676363B2 - テクネチウム９９ｍのプロピレンアミンオキシムとの複合体 - Google Patents

テクネチウム９９ｍのプロピレンアミンオキシムとの複合体

Info

Publication number
JPH0676363B2
JPH0676363B2 JP61053508A JP5350886A JPH0676363B2 JP H0676363 B2 JPH0676363 B2 JP H0676363B2 JP 61053508 A JP61053508 A JP 61053508A JP 5350886 A JP5350886 A JP 5350886A JP H0676363 B2 JPH0676363 B2 JP H0676363B2
Authority
JP
Japan
Prior art keywords
compound
complex
meso
diaza
oxime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61053508A
Other languages
English (en)
Japanese (ja)
Other versions
JPS61225159A (ja
Inventor
ルイス・ルーベン・キヤニング
デービツド・ピーター・ノウオトニツク
ルデイ・ドミニク・ネイリンクス
イアン・マイケル・パイパー
Original Assignee
アマーシヤム・インターナシヨナル・ピーエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506249A external-priority patent/GB8506249D0/en
Priority claimed from GB858509368A external-priority patent/GB8509368D0/en
Application filed by アマーシヤム・インターナシヨナル・ピーエルシー filed Critical アマーシヤム・インターナシヨナル・ピーエルシー
Publication of JPS61225159A publication Critical patent/JPS61225159A/ja
Publication of JPH0676363B2 publication Critical patent/JPH0676363B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP61053508A 1985-03-11 1986-03-11 テクネチウム９９ｍのプロピレンアミンオキシムとの複合体 Expired - Lifetime JPH0676363B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858506249A GB8506249D0 (en) 1985-03-11 1985-03-11 Complexes of technetium-99m
GB8506249 1985-04-12
GB8509368 1985-04-12
GB858509368A GB8509368D0 (en) 1985-04-12 1985-04-12 Complexes of technetium ggm

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP5202426A Division JP2547515B2 (ja) 1985-03-11 1993-08-16 テクネチウム９９ｍのプロピレンアミンオキシムとの錯体

Publications (2)

Publication Number Publication Date
JPS61225159A JPS61225159A (ja) 1986-10-06
JPH0676363B2 true JPH0676363B2 (ja) 1994-09-28

Family

ID=26288959

Family Applications (2)

Application Number Title Priority Date Filing Date
JP61053508A Expired - Lifetime JPH0676363B2 (ja) 1985-03-11 1986-03-11 テクネチウム９９ｍのプロピレンアミンオキシムとの複合体
JP5202426A Expired - Lifetime JP2547515B2 (ja) 1985-03-11 1993-08-16 テクネチウム９９ｍのプロピレンアミンオキシムとの錯体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP5202426A Expired - Lifetime JP2547515B2 (ja) 1985-03-11 1993-08-16 テクネチウム９９ｍのプロピレンアミンオキシムとの錯体

Country Status (7)

Country Link
US (1) US4789736A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0194843B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPH0676363B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU577931B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1243329A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3687467T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK97997A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601003D0 (en) * 1986-01-16 1986-02-19 Amersham Int Plc Labelling blood cells
GB8702062D0 (en) * 1987-01-30 1987-03-04 Amersham Int Plc Metal complexes for diagnosis & therapy
US4895960A (en) * 1989-01-23 1990-01-23 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
US5026829A (en) * 1989-01-23 1991-06-25 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
US5026913A (en) * 1989-12-12 1991-06-25 Medi-Physics, Inc. Hydrocarbylphenyl diaminodithiol derivatives
US5080884A (en) * 1989-12-12 1992-01-14 Medi-Physics, Inc. Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging
JP3005943B2 (ja) * 1990-04-17 2000-02-07 マリンクロッド・インコーポレイテッド テクネチウム―９９ｍ錯化合物製造のための方法及びキット
US5158760A (en) * 1990-05-30 1992-10-27 Board Of Regents, The University Of Texas System 99m TC labeled liposomes
US5143713A (en) * 1990-05-30 1992-09-01 Board Of Regents, The University Of Texas System 99m Tc labeled liposomes
US5252721A (en) * 1990-09-28 1993-10-12 Neorx Corporation S3 N chelating compounds
US5684137A (en) * 1990-09-28 1997-11-04 Neorx Corporation S3 N chelating compounds for the radiolabeling of ligands, anti-ligands or other proteins
US5116598A (en) * 1990-10-29 1992-05-26 Mallinckrodt Medical, Inc. N4 technetium-99 m complexes for use as radiopharmaceuticals
DE4107570A1 (de) * 1991-03-07 1992-11-19 Diagnostikforschung Inst Chelate, deren metallkomplexe sowie ihre verwendung in diagnostik und therapie
DE4107571A1 (de) * 1991-03-07 1992-11-19 Diagnostikforschung Inst Amid-chelate, deren metallkomplexe sowie ihre verwendung in diagnostik und therapie
IL103353A (en) * 1991-10-29 1999-01-26 Bracco Int Bv Ligand metal complexes thereof diagnostic composition and processes for their preparation
US5808091A (en) * 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
US6359120B1 (en) * 1991-10-29 2002-03-19 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia-localizing moiety
US5993774A (en) * 1992-10-08 1999-11-30 Amersham International Plc Metal-oxime chelates for use as radiopharmaceutical agents
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
CA2168652A1 (en) * 1993-08-04 1995-02-16 Colin Mill Archer Radiometal complexes that localise in hypoxic tissue
EP0688313B1 (en) * 1994-01-12 1998-04-08 BRACCO International B.V. Ligands and metal complexes thereof
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
EP1767224B1 (en) * 1995-12-01 2011-10-05 Molecular Insight Pharmaceuticals, Inc. Stereoisomers of fatty acid analogs for diagnostic imaging
US6005083A (en) 1997-03-28 1999-12-21 Neorx Corporation Bridged aromatic substituted amine ligands with donor atoms
KR100615893B1 (ko) * 1999-01-15 2006-08-25 동아제약주식회사 (알알, 에스에스)-4,8-디아자-3,6,6,9-테트라메틸운데칸-2,10-디
KR100632963B1 (ko) * 1999-01-15 2006-10-11 동아제약주식회사 광학활성을갖는(3알,9알)또는(3에스,9에스)-4,8-디아자-3,6,6,9-테트라메틸운데칸-2,10-디온비스옥심유도체의제조방법
WO2001005433A2 (en) 1999-07-14 2001-01-25 Board Of Regents, The University Of Texas System Delivery and retention of activity agents to lymph nodes
US20090187060A1 (en) 2008-01-22 2009-07-23 E-Z-Em, Inc. Method and Formulation for Neutralizing Toxic Chemicals and Materials
CU23844B1 (es) 2009-04-17 2012-10-15 Ct De Neurociencias De Cuba Procedimiento de obtención de nuevos derivados de naftaleno para el diagnóstico in vivo de la enfermedad de alzheimer
CA2942280C (en) 2014-03-27 2022-11-29 Jubilant Life Sciences Limited An improved process for the preparation of exametazime

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
JPS60238575A (ja) * 1984-05-08 1985-11-27 三菱プレシジヨン株式会社 油圧駆動式昇降階段装置
GB8426845D0 (en) * 1984-10-24 1984-11-28 Amersham Int Plc Complexes of technetium-99m

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ＡｃｔａＣｒｙｓｔａｌｌｏｇｒ．，Ｓｅｃｔ．Ｃ：Ｃｒｙｓｔ．Ｓｔｒｕｃｔ．Ｃｏｍｍｕｎ．，Ｃ４０（５），８１３−８１６（１９８４）
Ｉｎｔ．Ｊ．Ｎｕｃｌ．Ｍｅｄ．Ｂｉｏ１．，１２（２），１３３−１３４（１９８５）
ｌｎｏｒｇ．Ｃｈｅｍ．，６（１１），２０４３−２０４６（１９６７）

Also Published As

Publication number Publication date
EP0194843A2 (en) 1986-09-17
JPS61225159A (ja) 1986-10-06
AU5460986A (en) 1986-10-16
DE3687467D1 (de) 1993-02-25
JPH06184078A (ja) 1994-07-05
US4789736A (en) 1988-12-06
JP2547515B2 (ja) 1996-10-23
CA1252481C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-04-11
HK97997A (en) 1997-08-08
EP0194843A3 (en) 1988-03-23
AU577931B2 (en) 1988-10-06
CA1243329A (en) 1988-10-18
DE3687467T2 (de) 1993-04-29
EP0194843B1 (en) 1993-01-13

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