JPH0573727B2 - - Google Patents

Info

Publication number
JPH0573727B2
JPH0573727B2 JP59031552A JP3155284A JPH0573727B2 JP H0573727 B2 JPH0573727 B2 JP H0573727B2 JP 59031552 A JP59031552 A JP 59031552A JP 3155284 A JP3155284 A JP 3155284A JP H0573727 B2 JPH0573727 B2 JP H0573727B2
Authority
JP
Japan
Prior art keywords
solution
spherical
particle size
particles
crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59031552A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59182290A (ja
Inventor
Hinritsuhi Pitsuhi Kurausu
Meesuto Toomasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JPS59182290A publication Critical patent/JPS59182290A/ja
Publication of JPH0573727B2 publication Critical patent/JPH0573727B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Jellies, Jams, And Syrups (AREA)
JP59031552A 1983-02-23 1984-02-23 固形薬剤及びその製法 Granted JPS59182290A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3306250.1 1983-02-23
DE19833306250 DE3306250A1 (de) 1983-02-23 1983-02-23 Sphaerische einkristalle fuer pharmazeutische zwecke

Publications (2)

Publication Number Publication Date
JPS59182290A JPS59182290A (ja) 1984-10-17
JPH0573727B2 true JPH0573727B2 (OSRAM) 1993-10-15

Family

ID=6191601

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59031552A Granted JPS59182290A (ja) 1983-02-23 1984-02-23 固形薬剤及びその製法

Country Status (11)

Country Link
US (1) US4632843A (OSRAM)
EP (1) EP0119480B1 (OSRAM)
JP (1) JPS59182290A (OSRAM)
AT (1) ATE40291T1 (OSRAM)
AU (1) AU561079B2 (OSRAM)
CA (1) CA1220421A (OSRAM)
DE (2) DE3306250A1 (OSRAM)
ES (1) ES8504452A1 (OSRAM)
IL (1) IL71018A (OSRAM)
PT (1) PT78146B (OSRAM)
ZA (1) ZA841287B (OSRAM)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3775880D1 (OSRAM) * 1986-09-18 1992-02-20 London School Of Pharmacy Innovations Ltd., London, Gb
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
FR2613619B1 (fr) * 1987-04-07 1993-10-15 Recherche Informatique Pharmacie Medicaments, produits dietetiques ou produits d'hygiene sous forme de compositions pulverulentes obtenues par adsorption de principes actifs sur un sucre a dissolution rapide
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
GB8805695D0 (en) * 1988-03-10 1988-04-07 Nycomed As Enteric coated spheroidal granules
DE3911069A1 (de) * 1989-04-06 1990-10-11 Knoll Ag Einkristalle von ss-phenylpropiophenonen
DE4027927A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Brausekomponente und verfahren zu ihrer herstellung
JP3447042B2 (ja) * 1997-07-23 2003-09-16 フロイント産業株式会社 単一物質球形粒の製造方法
DE19834876A1 (de) * 1998-08-01 2000-02-03 Aventis Res & Tech Gmbh & Co Verfahren zur Herstellung sphärischer Teilchen bei der Kristallisation
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
EP1189599A2 (en) * 1999-06-11 2002-03-27 Eli Lilly And Company Pharmaceutical materials and methods for their preparation and use
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
FI20002217L (fi) * 1999-12-30 2001-07-01 Orion Yhtymae Oyj Inhalaatiopartikkelit
FI20010115A0 (fi) * 2001-01-18 2001-01-18 Orion Corp Menetelmä nanopartikkelien valmistamiseksi
MXPA04007995A (es) * 2002-02-19 2004-11-26 Teva Pharma Desolvatacion de solvatos de hemicalcio de atorvastatina.
DE10218110A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Arzneimittelhilfsstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
DE10218106A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Arzneimittelwirkstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
US20040028729A1 (en) * 2002-04-29 2004-02-12 Shojaei Amir H. Pharmaceutical formulations with improved bioavailability
AT504996B1 (de) * 2007-03-02 2009-03-15 Andritz Tech & Asset Man Gmbh Verfahren und vorrichtung zur trocknung von kristallinen carbonsäuren
US20080268018A1 (en) * 2007-04-30 2008-10-30 Pacetti Stephen D Method for forming crystallized therapeutic agents on a medical device
EP2223702B1 (en) * 2007-12-03 2019-05-08 Tomita Pharmaceutical Co., Ltd. Core particle for pharmaceutical preparation
CA2691554A1 (en) * 2010-02-01 2011-08-01 Michael Krautter Crystal growing device
US9905953B1 (en) 2016-09-30 2018-02-27 Slobodan Pavlovic High power spring-actuated electrical connector
MX2019003775A (es) * 2016-10-03 2019-07-01 Hoganas Ab Publ Aditivo alimenticio de hierro blanco.
KR102592165B1 (ko) 2018-02-26 2023-10-19 인벤티브 컨설팅 엘엘씨 고전력 응용을 위한 스프링 작동식 전기 커넥터
CN111498874B (zh) * 2020-02-21 2022-10-04 天津大学 一种大粒度碘化铯球晶及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA799930A (en) * 1968-11-26 Polderman Jacobus Process for rendering powders free flowing and the thus obtained powders
US2996431A (en) * 1953-12-16 1961-08-15 Barry Richard Henry Friable tablet and process for manufacturing same
US2853420A (en) * 1956-01-25 1958-09-23 Lowey Hans Ethyl cellulose coatings for shaped medicinal preparations
US3072533A (en) * 1960-11-15 1963-01-08 Henry J Johnson Crystalline vitamin d composition and method of preparing same
NL137432C (OSRAM) * 1964-08-13 1900-01-01
US3433872A (en) * 1966-11-25 1969-03-18 Hoffmann La Roche Palatable,free-flowing,non-agglomerating caffeine powder
FR7932M (OSRAM) * 1968-09-30 1970-05-19
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
CA942667A (en) * 1970-10-16 1974-02-26 Alejandro Zaffaroni Drug-delivery system
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
FR2171934B1 (OSRAM) * 1972-02-16 1974-09-13 Rhone Poulenc Sa
US4123382A (en) * 1973-05-25 1978-10-31 Merck & Co., Inc. Method of microencapsulation
JPS53124634A (en) * 1974-08-15 1978-10-31 Shin Nihon Kagaku Kogyo Kk Production of table salt
JPS51113813A (en) * 1975-03-03 1976-10-07 Towa Kasei Kogyo Kk Pulverizing process of maltitol
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
US4386120A (en) * 1980-01-07 1983-05-31 Nippon Kayaku Kabushiki Kaisha Process for producing polyacrylic acid salt granules easily soluble in water
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
US4259315A (en) * 1980-06-13 1981-03-31 A. H. Robins Company, Inc. Controlled release potassium dosage form
US4479911A (en) * 1982-01-28 1984-10-30 Sandoz, Inc. Process for preparation of microspheres and modification of release rate of core material

Also Published As

Publication number Publication date
PT78146A (en) 1984-03-01
ES529959A0 (es) 1985-04-16
ATE40291T1 (de) 1989-02-15
DE3306250A1 (de) 1984-08-23
IL71018A0 (en) 1984-05-31
IL71018A (en) 1987-01-30
AU561079B2 (en) 1987-04-30
PT78146B (en) 1986-05-19
DE3476337D1 (en) 1989-03-02
US4632843A (en) 1986-12-30
EP0119480B1 (de) 1989-01-25
AU2484384A (en) 1984-08-30
ZA841287B (en) 1984-10-31
CA1220421A (en) 1987-04-14
EP0119480A3 (en) 1985-09-25
ES8504452A1 (es) 1985-04-16
JPS59182290A (ja) 1984-10-17
EP0119480A2 (de) 1984-09-26

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