JPH0556817B2 - - Google Patents
Info
- Publication number
- JPH0556817B2 JPH0556817B2 JP60198568A JP19856885A JPH0556817B2 JP H0556817 B2 JPH0556817 B2 JP H0556817B2 JP 60198568 A JP60198568 A JP 60198568A JP 19856885 A JP19856885 A JP 19856885A JP H0556817 B2 JPH0556817 B2 JP H0556817B2
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- light
- antibody
- reaction
- antibody reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000006243 chemical reaction Methods 0.000 claims description 72
- 239000000427 antigen Substances 0.000 claims description 47
- 102000036639 antigens Human genes 0.000 claims description 46
- 108091007433 antigens Proteins 0.000 claims description 46
- 230000003595 spectral effect Effects 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 26
- 230000010287 polarization Effects 0.000 claims description 21
- 239000010419 fine particle Substances 0.000 claims description 17
- 230000008105 immune reaction Effects 0.000 claims description 16
- 238000001228 spectrum Methods 0.000 claims description 16
- 239000011859 microparticle Substances 0.000 claims description 14
- 238000001514 detection method Methods 0.000 claims description 6
- 238000000691 measurement method Methods 0.000 claims description 5
- 230000005855 radiation Effects 0.000 claims description 4
- 230000028993 immune response Effects 0.000 claims 1
- 230000036046 immunoreaction Effects 0.000 claims 1
- 239000002245 particle Substances 0.000 description 46
- 210000004027 cell Anatomy 0.000 description 20
- 238000005259 measurement Methods 0.000 description 16
- 230000002776 aggregation Effects 0.000 description 13
- 238000004220 aggregation Methods 0.000 description 13
- 238000012545 processing Methods 0.000 description 11
- 238000003018 immunoassay Methods 0.000 description 9
- 230000003287 optical effect Effects 0.000 description 8
- 230000005653 Brownian motion process Effects 0.000 description 7
- 238000005537 brownian motion Methods 0.000 description 7
- 239000003153 chemical reaction reagent Substances 0.000 description 7
- 238000010586 diagram Methods 0.000 description 7
- 230000033001 locomotion Effects 0.000 description 7
- 238000002372 labelling Methods 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 239000012295 chemical reaction liquid Substances 0.000 description 5
- 239000004816 latex Substances 0.000 description 5
- 229920000126 latex Polymers 0.000 description 5
- 230000035945 sensitivity Effects 0.000 description 5
- 239000004793 Polystyrene Substances 0.000 description 4
- 229940027941 immunoglobulin g Drugs 0.000 description 4
- 229920002223 polystyrene Polymers 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 230000001427 coherent effect Effects 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000005684 electric field Effects 0.000 description 3
- 229940084986 human chorionic gonadotropin Drugs 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 102000011022 Chorionic Gonadotropin Human genes 0.000 description 2
- 108010062540 Chorionic Gonadotropin Proteins 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000000951 immunodiffusion Effects 0.000 description 2
- 238000000760 immunoelectrophoresis Methods 0.000 description 2
- 229940099472 immunoglobulin a Drugs 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000003127 radioimmunoassay Methods 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 206010034972 Photosensitivity reaction Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 230000001032 anti-candidal effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 239000002955 immunomodulating agent Substances 0.000 description 1
- 229940121354 immunomodulator Drugs 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000011146 organic particle Substances 0.000 description 1
- 239000011242 organic-inorganic particle Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000036211 photosensitivity Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000013139 quantization Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000012883 sequential measurement Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010183 spectrum analysis Methods 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19856885A JPS6259841A (ja) | 1985-09-10 | 1985-09-10 | 直線偏光を用いる免疫反応の測定方法および装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19856885A JPS6259841A (ja) | 1985-09-10 | 1985-09-10 | 直線偏光を用いる免疫反応の測定方法および装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6259841A JPS6259841A (ja) | 1987-03-16 |
| JPH0556817B2 true JPH0556817B2 (de) | 1993-08-20 |
Family
ID=16393342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP19856885A Granted JPS6259841A (ja) | 1985-09-10 | 1985-09-10 | 直線偏光を用いる免疫反応の測定方法および装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6259841A (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0621868B2 (ja) * | 1989-09-26 | 1994-03-23 | 新技術事業団 | ヘテロダイン検波結像系及び該結像系を用いた光断層像画像化装置 |
| DE102015003019A1 (de) * | 2015-03-06 | 2016-09-08 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zur optischen Detektion einer Bewegung in einer biologischen Probe mit räumlicher Ausdehnung |
| JP6515617B2 (ja) * | 2015-03-20 | 2019-05-22 | コニカミノルタ株式会社 | 測定方法および測定装置 |
| JP7077175B2 (ja) | 2018-08-07 | 2022-05-30 | キヤノン株式会社 | 自動分析装置、自動分析方法、および、プログラム |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5282722A (en) * | 1975-12-26 | 1977-07-11 | Kotai Kasei Kk | Immunologically measuring method and apparatus |
| JPS5761947A (en) * | 1980-05-31 | 1982-04-14 | Giyuntaa Neraa Hansu | Apparatus for and method of determining existence of seed with fluorescent mark |
| JPS6165144A (ja) * | 1984-09-07 | 1986-04-03 | Olympus Optical Co Ltd | 光強度ゆらぎを用いる免疫反応測定装置 |
| JPS61271460A (ja) * | 1985-05-28 | 1986-12-01 | Olympus Optical Co Ltd | 免疫学的分析方法 |
-
1985
- 1985-09-10 JP JP19856885A patent/JPS6259841A/ja active Granted
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5282722A (en) * | 1975-12-26 | 1977-07-11 | Kotai Kasei Kk | Immunologically measuring method and apparatus |
| JPS5761947A (en) * | 1980-05-31 | 1982-04-14 | Giyuntaa Neraa Hansu | Apparatus for and method of determining existence of seed with fluorescent mark |
| JPS6165144A (ja) * | 1984-09-07 | 1986-04-03 | Olympus Optical Co Ltd | 光強度ゆらぎを用いる免疫反応測定装置 |
| JPS61271460A (ja) * | 1985-05-28 | 1986-12-01 | Olympus Optical Co Ltd | 免疫学的分析方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6259841A (ja) | 1987-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |