JPH0552896B2 - - Google Patents
Info
- Publication number
- JPH0552896B2 JPH0552896B2 JP60007038A JP703885A JPH0552896B2 JP H0552896 B2 JPH0552896 B2 JP H0552896B2 JP 60007038 A JP60007038 A JP 60007038A JP 703885 A JP703885 A JP 703885A JP H0552896 B2 JPH0552896 B2 JP H0552896B2
- Authority
- JP
- Japan
- Prior art keywords
- light
- objective lens
- focus
- flow cell
- photometric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 claims description 36
- 230000003287 optical effect Effects 0.000 claims description 24
- 238000004458 analytical method Methods 0.000 claims description 12
- 238000001514 detection method Methods 0.000 claims description 10
- 210000004027 cell Anatomy 0.000 description 17
- 238000005259 measurement Methods 0.000 description 14
- 238000010586 diagram Methods 0.000 description 7
- 238000003384 imaging method Methods 0.000 description 6
- 230000004888 barrier function Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000012491 analyte Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000007850 fluorescent dye Substances 0.000 description 2
- 238000005375 photometry Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/1452—Adjustment of focus; Alignment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60007038A JPS61165637A (ja) | 1985-01-18 | 1985-01-18 | 粒子解析装置 |
US06/818,263 US4690561A (en) | 1985-01-18 | 1986-01-13 | Particle analyzing apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60007038A JPS61165637A (ja) | 1985-01-18 | 1985-01-18 | 粒子解析装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61165637A JPS61165637A (ja) | 1986-07-26 |
JPH0552896B2 true JPH0552896B2 (zh) | 1993-08-06 |
Family
ID=11654870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60007038A Granted JPS61165637A (ja) | 1985-01-18 | 1985-01-18 | 粒子解析装置 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS61165637A (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008111833A (ja) * | 2007-10-02 | 2008-05-15 | Toyobo Co Ltd | 尿中有形成分分類装置 |
WO2016133760A1 (en) * | 2015-02-18 | 2016-08-25 | Becton, Dickinson And Company | Optical detection systems and methods of using the same |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5322787A (en) * | 1976-08-16 | 1978-03-02 | Hitachi Ltd | Measuring apparatus for corpuscle |
JPS5386298A (en) * | 1976-11-05 | 1978-07-29 | Leeds & Northrup Co | Measuring method and apparatus for volume and volumetric distribution of fine particles |
JPS59107238A (ja) * | 1982-12-10 | 1984-06-21 | Hitachi Ltd | 光散乱を用いた粒子測定装置 |
JPS59184840A (ja) * | 1983-04-06 | 1984-10-20 | Mitsubishi Chem Ind Ltd | 液体中のダスト測定法及びその装置 |
-
1985
- 1985-01-18 JP JP60007038A patent/JPS61165637A/ja active Granted
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5322787A (en) * | 1976-08-16 | 1978-03-02 | Hitachi Ltd | Measuring apparatus for corpuscle |
JPS5386298A (en) * | 1976-11-05 | 1978-07-29 | Leeds & Northrup Co | Measuring method and apparatus for volume and volumetric distribution of fine particles |
JPS59107238A (ja) * | 1982-12-10 | 1984-06-21 | Hitachi Ltd | 光散乱を用いた粒子測定装置 |
JPS59184840A (ja) * | 1983-04-06 | 1984-10-20 | Mitsubishi Chem Ind Ltd | 液体中のダスト測定法及びその装置 |
Also Published As
Publication number | Publication date |
---|---|
JPS61165637A (ja) | 1986-07-26 |
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