JPH0513927B2 - - Google Patents
Info
- Publication number
- JPH0513927B2 JPH0513927B2 JP58192160A JP19216083A JPH0513927B2 JP H0513927 B2 JPH0513927 B2 JP H0513927B2 JP 58192160 A JP58192160 A JP 58192160A JP 19216083 A JP19216083 A JP 19216083A JP H0513927 B2 JPH0513927 B2 JP H0513927B2
- Authority
- JP
- Japan
- Prior art keywords
- coating
- methylcellulose
- hydroxypropyl methylcellulose
- coated
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000576 coating method Methods 0.000 claims description 18
- 239000011248 coating agent Substances 0.000 claims description 17
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 14
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 14
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 14
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 14
- 229920000609 methyl cellulose Polymers 0.000 claims description 11
- 239000001923 methylcellulose Substances 0.000 claims description 11
- 239000007787 solid Substances 0.000 claims description 8
- 239000003814 drug Substances 0.000 claims description 7
- 229940079593 drug Drugs 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 4
- 239000008199 coating composition Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 description 9
- -1 methoxyl groups Chemical group 0.000 description 6
- 239000007864 aqueous solution Substances 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 239000000576 food coloring agent Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000263375 Vanilla tahitensis Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 206010048245 Yellow skin Diseases 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- UJMBCXLDXJUMFB-UHFFFAOYSA-K trisodium;5-oxo-1-(4-sulfonatophenyl)-4-[(4-sulfonatophenyl)diazenyl]-4h-pyrazole-3-carboxylate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)C1=NN(C=2C=CC(=CC=2)S([O-])(=O)=O)C(=O)C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 UJMBCXLDXJUMFB-UHFFFAOYSA-K 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19216083A JPS6084216A (ja) | 1983-10-14 | 1983-10-14 | 固形薬剤被覆用組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19216083A JPS6084216A (ja) | 1983-10-14 | 1983-10-14 | 固形薬剤被覆用組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6084216A JPS6084216A (ja) | 1985-05-13 |
| JPH0513927B2 true JPH0513927B2 (fr) | 1993-02-23 |
Family
ID=16286686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP19216083A Granted JPS6084216A (ja) | 1983-10-14 | 1983-10-14 | 固形薬剤被覆用組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6084216A (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0554251U (ja) * | 1991-12-26 | 1993-07-20 | 共同印刷株式会社 | カッターつきロール収納用カートン |
| JPH0711527U (ja) * | 1993-08-02 | 1995-02-21 | 本州製紙株式会社 | 切歯付きカートン |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5740804A (en) * | 1980-08-22 | 1982-03-06 | Tokyo Shibaura Electric Co | Conductive paste |
| JPS5826816A (ja) * | 1981-08-11 | 1983-02-17 | Teisan Seiyaku Kk | 球形顆粒からなる持続性複合顆粒剤 |
-
1983
- 1983-10-14 JP JP19216083A patent/JPS6084216A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5740804A (en) * | 1980-08-22 | 1982-03-06 | Tokyo Shibaura Electric Co | Conductive paste |
| JPS5826816A (ja) * | 1981-08-11 | 1983-02-17 | Teisan Seiyaku Kk | 球形顆粒からなる持続性複合顆粒剤 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0554251U (ja) * | 1991-12-26 | 1993-07-20 | 共同印刷株式会社 | カッターつきロール収納用カートン |
| JPH0711527U (ja) * | 1993-08-02 | 1995-02-21 | 本州製紙株式会社 | 切歯付きカートン |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6084216A (ja) | 1985-05-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4083949A (en) | New oral form of medicament and a method for producing it | |
| EP0533297B1 (fr) | Formulation pharmaceutique à libération contrÔlée | |
| JP2773959B2 (ja) | 大腸内放出性固形製剤 | |
| KR0155563B1 (ko) | 대장 붕괴성 경질 캡슐 | |
| US5576022A (en) | Controlled release tacrine drug delivery systems and methods for preparing same | |
| US3538214A (en) | Controlled release medicinal tablets | |
| RU2201217C2 (ru) | Таблетка с энтеросолюбильным покрытием и способ приготовления | |
| CA2342340C (fr) | Nouvelles formulations administrees par voie orale et a liberation prolongee | |
| US3957523A (en) | Coating compositions for solid medicines | |
| US4806361A (en) | Medicaments in sustained release unit dose form | |
| JPH09505609A (ja) | アジスロマイシンの放出調節された剤形 | |
| PL188834B1 (pl) | Farmaceutyczne formulacje zawierające tramadol lub jego fizjologicznie akceptowane sole oraz sposóbwytwarzania tych formulacji | |
| PT85819B (pt) | Processo para a preparacao de membranas de revestimento e de composicoes farmaceuticas obtidas a partir delas | |
| CZ20021529A3 (cs) | Orální dávkovací formy obsahující oxcarbazepin | |
| KR970007899B1 (ko) | 맛 은폐를 위한 수단을 포함하는 저작가능한 의약 정제 | |
| JPH02288821A (ja) | 作用物質を含有する皮膜被覆された粒子及び医薬製剤 | |
| JPH0624962A (ja) | 腸溶徐放性製剤 | |
| CA2634006C (fr) | Compositions pharmaceutiques a liberation prolongee comprenant de la liothyronine ou du sel de sodium de liothronine | |
| JPH03145418A (ja) | 塩基性薬物塩酸塩の徐放性製剤 | |
| JPH0513927B2 (fr) | ||
| US3244596A (en) | Coated medicinal agents and coating compositions therefor | |
| JP2002003366A (ja) | 固形薬剤用水系コーティング剤組成物 | |
| CN1717252B (zh) | 含有碱性药物的制剂 | |
| EP1235556A2 (fr) | Compositions d'enrobage masquant le gout | |
| JPS6013719A (ja) | 被覆固形薬剤 |