JPH04365484A - 固定化ｄ−アミノ酸オキシダーゼおよび医薬の製造のためのその使用 - Google Patents

固定化ｄ−アミノ酸オキシダーゼおよび医薬の製造のためのその使用

Info

Publication number
JPH04365484A
JPH04365484A JP3337430A JP33743091A JPH04365484A JP H04365484 A JPH04365484 A JP H04365484A JP 3337430 A JP3337430 A JP 3337430A JP 33743091 A JP33743091 A JP 33743091A JP H04365484 A JPH04365484 A JP H04365484A
Authority
JP
Japan
Prior art keywords
group
amino acid
carbon atoms
acid oxidase
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3337430A
Other languages
English (en)
Japanese (ja)
Inventor
Klaus Sauber
クラウス・ザウバー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPH04365484A publication Critical patent/JPH04365484A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/18—Multi-enzyme systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP3337430A 1990-12-24 1991-12-20 固定化ｄ−アミノ酸オキシダーゼおよび医薬の製造のためのその使用 Pending JPH04365484A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4041755 1990-12-24
DE40417557 1990-12-24

Publications (1)

Publication Number Publication Date
JPH04365484A true JPH04365484A (ja) 1992-12-17

Family

ID=6421427

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3337430A Pending JPH04365484A (ja) 1990-12-24 1991-12-20 固定化ｄ−アミノ酸オキシダーゼおよび医薬の製造のためのその使用

Country Status (11)

Country Link
US (1) US5599702A (enExample)
EP (1) EP0492495A3 (enExample)
JP (1) JPH04365484A (enExample)
KR (1) KR920012449A (enExample)
AU (1) AU660438B2 (enExample)
CA (1) CA2058194A1 (enExample)
CZ (1) CZ284454B6 (enExample)
MX (1) MX9102792A (enExample)
NZ (1) NZ241116A (enExample)
TW (1) TW198064B (enExample)
ZA (1) ZA9110119B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009503203A (ja) * 2005-08-03 2009-01-29 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 親水性架橋ポリマー

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4342770A1 (de) * 1993-12-15 1995-07-06 Boehringer Mannheim Gmbh Trägerfixierte Enzyme
US5980883A (en) * 1996-10-02 1999-11-09 Kuraray Co., Ltd. Polymer gel for medical use
KR100481138B1 (ko) * 1997-09-09 2005-04-11 바이오케미 게젤샤프트 엠베하 효소 활성을 갖는 미생물을 함유하는 구형 입자 및 구형 입자의 제조방법
AU2002310863A1 (en) * 2001-04-19 2002-11-05 Bioferma Murcia, S.A. Enzymatic process for preparing cephalosporanic acid derivatives using alpha-ketoacid derivatives
EP1754534A1 (de) * 2005-08-03 2007-02-21 MERCK PATENT GmbH Hydrophiles vernetztes Polymer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1385685A (en) * 1971-04-21 1975-02-26 Glaxo Lab Ltd Cephalosporin derivatives
DE2911192A1 (de) * 1979-03-22 1980-10-02 Boehringer Sohn Ingelheim Neuartiges immobilisiertes glucoseoxidase-katalasepraeparat und seine verwendung zur enzymatischen glucoseoxidation
DE3404021A1 (de) * 1983-05-28 1984-11-29 Hoechst Ag, 6230 Frankfurt Makroporoese perlpolymerisate, verfahren zu ihrer herstellung und ihre anwendung
DE3344912A1 (de) * 1983-12-13 1985-06-20 Hoechst Ag, 6230 Frankfurt Vernetzte polymerisate, verfahren zu ihrer herstellung und ihre anwendung
SE8500157D0 (sv) * 1985-01-11 1985-01-11 Mosbach Klaus Isolation and partial characterization of a d-amino acid oxidase active against cephalosporin c from the yeast trigonopsis variabilis
DE3629177A1 (de) * 1986-08-28 1988-03-17 Hoechst Ag Vernetzte polymerisate und verfahren zu ihrer herstellung
DE3818851A1 (de) * 1988-06-03 1989-12-14 Hoechst Ag Neue transaminase, ihre herstellung und ihre verwendung
DE4028119C1 (enExample) * 1990-09-05 1991-12-05 Hoechst Ag, 6230 Frankfurt, De
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009503203A (ja) * 2005-08-03 2009-01-29 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 親水性架橋ポリマー

Also Published As

Publication number Publication date
AU660438B2 (en) 1995-06-29
CS399591A3 (en) 1992-11-18
EP0492495A3 (en) 1993-06-16
TW198064B (enExample) 1993-01-11
US5599702A (en) 1997-02-04
ZA9110119B (en) 1992-09-30
CZ284454B6 (cs) 1998-12-16
CA2058194A1 (en) 1992-06-25
KR920012449A (ko) 1992-07-27
AU8989591A (en) 1992-06-25
NZ241116A (en) 1993-11-25
EP0492495A2 (de) 1992-07-01
MX9102792A (es) 1992-06-01

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