JPH0320222A - 脳内虚血症治療剤 - Google Patents

脳内虚血症治療剤

Info

Publication number
JPH0320222A
JPH0320222A JP2141755A JP14175590A JPH0320222A JP H0320222 A JPH0320222 A JP H0320222A JP 2141755 A JP2141755 A JP 2141755A JP 14175590 A JP14175590 A JP 14175590A JP H0320222 A JPH0320222 A JP H0320222A
Authority
JP
Japan
Prior art keywords
disease
agent according
brain
ischemia
stroke
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2141755A
Other languages
English (en)
Japanese (ja)
Inventor
Christopher G Boissard
クリストフアー　ジー　ボイサード
Duncan P Taylor
ダンカン　ピー　テイラー
Michael S Eison
マイケル　エス　エイソン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of JPH0320222A publication Critical patent/JPH0320222A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2141755A 1989-06-01 1990-06-01 脳内虚血症治療剤 Pending JPH0320222A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/360,658 US5055470A (en) 1989-06-01 1989-06-01 Method of treatment of ischemia in brain
US360658 1989-06-01

Publications (1)

Publication Number Publication Date
JPH0320222A true JPH0320222A (ja) 1991-01-29

Family

ID=23418925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2141755A Pending JPH0320222A (ja) 1989-06-01 1990-06-01 脳内虚血症治療剤

Country Status (8)

Country Link
US (1) US5055470A (Direct)
EP (1) EP0410114A3 (Direct)
JP (1) JPH0320222A (Direct)
KR (1) KR910000151A (Direct)
CA (1) CA2017781A1 (Direct)
HU (1) HU205856B (Direct)
IL (1) IL94525A0 (Direct)
TW (1) TW198681B (Direct)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007500757A (ja) * 2003-06-12 2007-01-18 株式会社エムズサイエンス 神経再生及び機能回復のためのシグマリガンド
JP2009516650A (ja) * 2005-11-01 2009-04-23 株式会社エムズサイエンス 神経再生及び機能回復のためのシグマリガンド

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424179A3 (en) * 1989-10-20 1991-12-27 John William Olney Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration
US5512584A (en) * 1991-04-16 1996-04-30 Basf Aktiengesellschaft 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof
IL103499A0 (en) * 1991-10-24 1993-03-15 Bristol Myers Squibb Co Pharmaceutical compositions for treating anxiety in benzodiazepine withdrawn patients
DE4219973A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
PT647137E (pt) * 1992-06-22 2008-11-24 Univ California Antagonistas dos receptores da glicina e a sua utilização
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
US6123956A (en) * 1997-07-10 2000-09-26 Keith Baker Methods for universally distributing therapeutic agents to the brain
CA2696398C (en) * 2007-08-21 2018-05-08 Midwestern University Methods for treatment of stroke or cerebrovascular accidents using an etb receptor agonist
CN102458399B (zh) 2009-04-30 2014-04-23 美国中西部大学 centhaquin的新制药用途
CA2917325C (en) 2013-07-08 2023-09-05 Midwestern University Compositions and methods for treating neuropsychiatric disorders using an endothelin-b receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007500757A (ja) * 2003-06-12 2007-01-18 株式会社エムズサイエンス 神経再生及び機能回復のためのシグマリガンド
JP2009516650A (ja) * 2005-11-01 2009-04-23 株式会社エムズサイエンス 神経再生及び機能回復のためのシグマリガンド

Also Published As

Publication number Publication date
KR910000151A (ko) 1991-01-29
US5055470A (en) 1991-10-08
CA2017781A1 (en) 1990-12-01
EP0410114A3 (en) 1992-01-02
TW198681B (Direct) 1993-01-21
HUT54050A (en) 1991-01-28
EP0410114A2 (en) 1991-01-30
IL94525A0 (en) 1991-03-10
HU205856B (en) 1992-07-28
HU903291D0 (en) 1990-10-28

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