JPH0242508B2 - - Google Patents
Info
- Publication number
- JPH0242508B2 JPH0242508B2 JP62280989A JP28098987A JPH0242508B2 JP H0242508 B2 JPH0242508 B2 JP H0242508B2 JP 62280989 A JP62280989 A JP 62280989A JP 28098987 A JP28098987 A JP 28098987A JP H0242508 B2 JPH0242508 B2 JP H0242508B2
- Authority
- JP
- Japan
- Prior art keywords
- resin composition
- hard resin
- medical
- general formula
- medical device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- -1 triglyceride compound Chemical class 0.000 claims description 74
- 210000004369 blood Anatomy 0.000 claims description 71
- 239000008280 blood Substances 0.000 claims description 71
- 239000011342 resin composition Substances 0.000 claims description 65
- 229920005989 resin Polymers 0.000 claims description 33
- 239000011347 resin Substances 0.000 claims description 33
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 19
- 125000001931 aliphatic group Chemical group 0.000 claims description 17
- 229920001577 copolymer Polymers 0.000 claims description 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 15
- 229910052799 carbon Inorganic materials 0.000 claims description 15
- 125000004432 carbon atom Chemical group C* 0.000 claims description 15
- 229920006230 thermoplastic polyester resin Polymers 0.000 claims description 14
- 239000004925 Acrylic resin Substances 0.000 claims description 13
- 229920000178 Acrylic resin Polymers 0.000 claims description 13
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 claims description 12
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 12
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 12
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims description 11
- 229920005672 polyolefin resin Polymers 0.000 claims description 10
- 239000004793 Polystyrene Substances 0.000 claims description 9
- 229920000515 polycarbonate Polymers 0.000 claims description 9
- 239000004417 polycarbonate Substances 0.000 claims description 9
- 229920002223 polystyrene Polymers 0.000 claims description 9
- 239000004743 Polypropylene Substances 0.000 claims description 7
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 claims description 7
- 229920001893 acrylonitrile styrene Polymers 0.000 claims description 7
- 229920001519 homopolymer Polymers 0.000 claims description 7
- 229920001707 polybutylene terephthalate Polymers 0.000 claims description 7
- 229920001155 polypropylene Polymers 0.000 claims description 7
- SCUZVMOVTVSBLE-UHFFFAOYSA-N prop-2-enenitrile;styrene Chemical compound C=CC#N.C=CC1=CC=CC=C1 SCUZVMOVTVSBLE-UHFFFAOYSA-N 0.000 claims description 7
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 claims description 6
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 claims description 6
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 6
- GYCMBHHDWRMZGG-UHFFFAOYSA-N Methylacrylonitrile Chemical compound CC(=C)C#N GYCMBHHDWRMZGG-UHFFFAOYSA-N 0.000 claims description 6
- 239000004698 Polyethylene Substances 0.000 claims description 6
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 claims description 6
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 claims description 6
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 claims description 6
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims description 6
- 229920000573 polyethylene Polymers 0.000 claims description 6
- 206010018910 Haemolysis Diseases 0.000 description 17
- 230000008588 hemolysis Effects 0.000 description 17
- 210000003743 erythrocyte Anatomy 0.000 description 13
- 230000000694 effects Effects 0.000 description 12
- 210000004204 blood vessel Anatomy 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 5
- 239000008188 pellet Substances 0.000 description 5
- 102000001554 Hemoglobins Human genes 0.000 description 4
- 108010054147 Hemoglobins Proteins 0.000 description 4
- 229920001890 Novodur Polymers 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 239000012503 blood component Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000000704 physical effect Effects 0.000 description 3
- VMPHSYLJUKZBJJ-UHFFFAOYSA-N trilaurin Chemical compound CCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC VMPHSYLJUKZBJJ-UHFFFAOYSA-N 0.000 description 3
- NWLYNHIRBSNTBX-UHFFFAOYSA-N C(CCCCCCC)(=O)C(O)(C(O)C(O)C(C(CCCC)CC)=O)C(C(CCCC)CC)=O Chemical compound C(CCCCCCC)(=O)C(O)(C(O)C(O)C(C(CCCC)CC)=O)C(C(CCCC)CC)=O NWLYNHIRBSNTBX-UHFFFAOYSA-N 0.000 description 2
- 239000004803 Di-2ethylhexylphthalate Substances 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 229920002239 polyacrylonitrile Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- CLPQOSOXCRHOBP-UHFFFAOYSA-N 13-decanoyl-13,14,15-trihydroxyheptacosane-12,16-dione Chemical compound C(CCCCCCCCC)(=O)C(O)(C(O)C(O)C(CCCCCCCCCCC)=O)C(CCCCCCCCCCC)=O CLPQOSOXCRHOBP-UHFFFAOYSA-N 0.000 description 1
- PZJLFHDNXGAZHU-UHFFFAOYSA-N 2,3-di(pentanoyloxy)propyl pentanoate Chemical compound CCCCC(=O)OCC(OC(=O)CCCC)COC(=O)CCCC PZJLFHDNXGAZHU-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- ASVSVHJPHSOVOZ-UHFFFAOYSA-N C(C)C(C(=O)C(C(C(O)C(CCCCCCCCC)=O)O)(O)C(C(CCCC)CC)=O)CCCC Chemical compound C(C)C(C(=O)C(C(C(O)C(CCCCCCCCC)=O)O)(O)C(C(CCCC)CC)=O)CCCC ASVSVHJPHSOVOZ-UHFFFAOYSA-N 0.000 description 1
- LVRSDBRQMFSPAH-UHFFFAOYSA-N C(C)C(C(=O)C(O)(C(O)C(O)C(CCCCCCCCC)=O)C(CCCCCCCCC)=O)CCCC Chemical compound C(C)C(C(=O)C(O)(C(O)C(O)C(CCCCCCCCC)=O)C(CCCCCCCCC)=O)CCCC LVRSDBRQMFSPAH-UHFFFAOYSA-N 0.000 description 1
- NLSGMSNLMIZVFL-UHFFFAOYSA-N C(CCC)(=O)C(O)(C(O)C(O)C(CC(C)C)=O)C(CC(C)C)=O Chemical compound C(CCC)(=O)C(O)(C(O)C(O)C(CC(C)C)=O)C(CC(C)C)=O NLSGMSNLMIZVFL-UHFFFAOYSA-N 0.000 description 1
- QUCJIIJJZCXMSW-UHFFFAOYSA-N C(CCC)(=O)C(O)(C(O)C(O)C(CCCC)=O)C(CCCC)=O Chemical compound C(CCC)(=O)C(O)(C(O)C(O)C(CCCC)=O)C(CCCC)=O QUCJIIJJZCXMSW-UHFFFAOYSA-N 0.000 description 1
- YQTFPIYVPSZSDV-UHFFFAOYSA-N C(CCCC)(=O)C(O)(C(O)C(O)C(CCCCC)=O)C(CCCCC)=O Chemical compound C(CCCC)(=O)C(O)(C(O)C(O)C(CCCCC)=O)C(CCCCC)=O YQTFPIYVPSZSDV-UHFFFAOYSA-N 0.000 description 1
- ZBKMFDQBTQFWQT-UHFFFAOYSA-N C(CCCCC)(=O)C(O)(C(O)C(O)C(C(CCCC)CC)=O)C(C(CCCC)CC)=O Chemical compound C(CCCCC)(=O)C(O)(C(O)C(O)C(C(CCCC)CC)=O)C(C(CCCC)CC)=O ZBKMFDQBTQFWQT-UHFFFAOYSA-N 0.000 description 1
- XPLSHXPYSGIASY-UHFFFAOYSA-N C(CCCCC)(=O)C(O)(C(O)C(O)C(CCCCCCC)=O)C(CCCCCCC)=O Chemical compound C(CCCCC)(=O)C(O)(C(O)C(O)C(CCCCCCC)=O)C(CCCCCCC)=O XPLSHXPYSGIASY-UHFFFAOYSA-N 0.000 description 1
- WBOKPDRICXKPKQ-UHFFFAOYSA-N C(CCCCCCC)(=O)C(C(C(O)C(C(CCCC)CC)=O)O)(O)C(CCCCCCC)=O Chemical compound C(CCCCCCC)(=O)C(C(C(O)C(C(CCCC)CC)=O)O)(O)C(CCCCCCC)=O WBOKPDRICXKPKQ-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- HZGMZSCMYSGJTL-UHFFFAOYSA-N isovaleric acid triglyceride Natural products CC(C)CC(=O)OCC(OC(=O)CC(C)C)COC(=O)CC(C)C HZGMZSCMYSGJTL-UHFFFAOYSA-N 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 229920005990 polystyrene resin Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- MAYCICSNZYXLHB-UHFFFAOYSA-N tricaproin Chemical compound CCCCCC(=O)OCC(OC(=O)CCCCC)COC(=O)CCCCC MAYCICSNZYXLHB-UHFFFAOYSA-N 0.000 description 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Materials For Medical Uses (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62280989A JPH01124462A (ja) | 1987-11-09 | 1987-11-09 | 医療用硬質樹脂組成物および医療用具 |
| DE3855956T DE3855956T2 (de) | 1987-01-13 | 1988-01-11 | Verwendung einer Triglyceridverbindung als Hämolysishemmer |
| EP92203200A EP0537863B1 (en) | 1987-01-13 | 1988-01-11 | Use of a triglyceride compound as a hemolysis depressant |
| DE8888900798T DE3880480T2 (de) | 1987-01-13 | 1988-01-11 | Hemolyse-inhibitor und plastifizierungsmittel. |
| PCT/JP1988/000020 WO1988005302A1 (fr) | 1987-01-13 | 1988-01-11 | Inhibiteur d'hemolyse et plastifiant |
| AU11032/88A AU610120B2 (en) | 1987-01-13 | 1988-01-11 | Hemolysis depressent and blood preserving composition |
| US07/391,502 US5079002A (en) | 1987-01-13 | 1988-01-11 | Hemolysis depressant and plasticizer |
| EP88900798A EP0340305B1 (en) | 1987-01-13 | 1988-01-11 | Hemolysis inhibitor and plasticizer |
| ES8800079A ES2010239A6 (es) | 1987-01-13 | 1988-01-13 | Perfeccionamientos en la fabricacion de resinas para articulos medicos. |
| US07/769,378 US5248531A (en) | 1987-01-13 | 1991-10-01 | Hemolysis depressant and plasticizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62280989A JPH01124462A (ja) | 1987-11-09 | 1987-11-09 | 医療用硬質樹脂組成物および医療用具 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01124462A JPH01124462A (ja) | 1989-05-17 |
| JPH0242508B2 true JPH0242508B2 (enrdf_load_stackoverflow) | 1990-09-25 |
Family
ID=17632705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62280989A Granted JPH01124462A (ja) | 1987-01-13 | 1987-11-09 | 医療用硬質樹脂組成物および医療用具 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01124462A (enrdf_load_stackoverflow) |
-
1987
- 1987-11-09 JP JP62280989A patent/JPH01124462A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01124462A (ja) | 1989-05-17 |