JPH0242505B2 - - Google Patents
Info
- Publication number
- JPH0242505B2 JPH0242505B2 JP62263697A JP26369787A JPH0242505B2 JP H0242505 B2 JPH0242505 B2 JP H0242505B2 JP 62263697 A JP62263697 A JP 62263697A JP 26369787 A JP26369787 A JP 26369787A JP H0242505 B2 JPH0242505 B2 JP H0242505B2
- Authority
- JP
- Japan
- Prior art keywords
- ether
- resin composition
- medical
- hard resin
- glycerin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 110
- -1 ether compound Chemical class 0.000 claims description 84
- 210000004369 blood Anatomy 0.000 claims description 75
- 239000008280 blood Substances 0.000 claims description 75
- 239000011342 resin composition Substances 0.000 claims description 69
- 150000002430 hydrocarbons Chemical group 0.000 claims description 47
- 229920005989 resin Polymers 0.000 claims description 38
- 239000011347 resin Substances 0.000 claims description 38
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 25
- 125000001033 ether group Chemical group 0.000 claims description 25
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 24
- 239000001301 oxygen Substances 0.000 claims description 24
- 229910052760 oxygen Inorganic materials 0.000 claims description 24
- 125000004432 carbon atom Chemical group C* 0.000 claims description 21
- 229920001577 copolymer Polymers 0.000 claims description 15
- 239000004925 Acrylic resin Substances 0.000 claims description 14
- 229920000178 Acrylic resin Polymers 0.000 claims description 14
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 claims description 14
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 14
- 229920006230 thermoplastic polyester resin Polymers 0.000 claims description 14
- 235000011187 glycerol Nutrition 0.000 claims description 13
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 12
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 12
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 claims description 11
- 229920005672 polyolefin resin Polymers 0.000 claims description 11
- 239000004793 Polystyrene Substances 0.000 claims description 9
- 229920000515 polycarbonate Polymers 0.000 claims description 9
- 239000004417 polycarbonate Substances 0.000 claims description 9
- 229920002223 polystyrene Polymers 0.000 claims description 9
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 claims description 8
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 claims description 8
- 150000002170 ethers Chemical class 0.000 claims description 8
- 229920001519 homopolymer Polymers 0.000 claims description 8
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 claims description 7
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 7
- GYCMBHHDWRMZGG-UHFFFAOYSA-N Methylacrylonitrile Chemical compound CC(=C)C#N GYCMBHHDWRMZGG-UHFFFAOYSA-N 0.000 claims description 7
- 239000004743 Polypropylene Substances 0.000 claims description 7
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 claims description 7
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 claims description 7
- 229920001893 acrylonitrile styrene Polymers 0.000 claims description 7
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 claims description 7
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims description 7
- 229920001707 polybutylene terephthalate Polymers 0.000 claims description 7
- 229920001155 polypropylene Polymers 0.000 claims description 7
- SCUZVMOVTVSBLE-UHFFFAOYSA-N prop-2-enenitrile;styrene Chemical compound C=CC#N.C=CC1=CC=CC=C1 SCUZVMOVTVSBLE-UHFFFAOYSA-N 0.000 claims description 7
- 239000004698 Polyethylene Substances 0.000 claims description 6
- 229920000573 polyethylene Polymers 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 36
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 34
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 18
- 206010018910 Haemolysis Diseases 0.000 description 16
- 230000008588 hemolysis Effects 0.000 description 16
- 210000003743 erythrocyte Anatomy 0.000 description 14
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 description 12
- 238000002474 experimental method Methods 0.000 description 11
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 10
- 238000012360 testing method Methods 0.000 description 8
- 210000004204 blood vessel Anatomy 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 229920001890 Novodur Polymers 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 102000001554 Hemoglobins Human genes 0.000 description 5
- 108010054147 Hemoglobins Proteins 0.000 description 5
- 239000008188 pellet Substances 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- LQXBZWFNAKZUNM-UHFFFAOYSA-N 16-methyl-1-(16-methylheptadecoxy)heptadecane Chemical compound CC(C)CCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCC(C)C LQXBZWFNAKZUNM-UHFFFAOYSA-N 0.000 description 4
- 230000000704 physical effect Effects 0.000 description 4
- QGCFQTWMBUKZFW-UHFFFAOYSA-N 1-butoxy-16-methylheptadecane Chemical compound C(CCC)OCCCCCCCCCCCCCCCC(C)C QGCFQTWMBUKZFW-UHFFFAOYSA-N 0.000 description 3
- 238000010241 blood sampling Methods 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 238000001746 injection moulding Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- HDSGGLDPANXUOY-UHFFFAOYSA-N 16-methyl-1-propan-2-yloxyheptadecane Chemical compound CC(C)CCCCCCCCCCCCCCCOC(C)C HDSGGLDPANXUOY-UHFFFAOYSA-N 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
- 239000012503 blood component Substances 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 150000002431 hydrogen Chemical class 0.000 description 2
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 229920002239 polyacrylonitrile Polymers 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- BKICBCVRTYZWEG-UHFFFAOYSA-N 1,2,3-tri(propan-2-yloxy)propane Chemical compound CC(C)OCC(OC(C)C)COC(C)C BKICBCVRTYZWEG-UHFFFAOYSA-N 0.000 description 1
- INGPBNRWXYGPKB-UHFFFAOYSA-N 1-(2-butoxyethoxy)-3-methylbutane Chemical compound CCCCOCCOCCC(C)C INGPBNRWXYGPKB-UHFFFAOYSA-N 0.000 description 1
- CIDHFUQBCBSBRO-UHFFFAOYSA-N 1-[2,3-bis(2-methylpropoxy)propoxy]-2-methylpropane Chemical compound CC(C)COCC(OCC(C)C)COCC(C)C CIDHFUQBCBSBRO-UHFFFAOYSA-N 0.000 description 1
- FJUBOZROYNKIMV-UHFFFAOYSA-N 1-[2,3-bis(3-methylbutoxy)propoxy]-3-methylbutane Chemical compound CC(C)CCOCC(OCCC(C)C)COCCC(C)C FJUBOZROYNKIMV-UHFFFAOYSA-N 0.000 description 1
- FJJACTGBBKXRDK-UHFFFAOYSA-N 1-[2-(2-butoxyethoxy)ethoxy]-3-methylbutane Chemical compound CCCCOCCOCCOCCC(C)C FJJACTGBBKXRDK-UHFFFAOYSA-N 0.000 description 1
- HBXWUCXDUUJDRB-UHFFFAOYSA-N 1-octadecoxyoctadecane Chemical compound CCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCC HBXWUCXDUUJDRB-UHFFFAOYSA-N 0.000 description 1
- FLWPLEJBOIQGBW-UHFFFAOYSA-N 16-methyl-1-(2-methylpropoxy)heptadecane Chemical compound C(C(C)C)OCCCCCCCCCCCCCCCC(C)C FLWPLEJBOIQGBW-UHFFFAOYSA-N 0.000 description 1
- OVZBYIWZUUXJMN-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethanol Chemical compound OCCOCCO.OCCOCCO OVZBYIWZUUXJMN-UHFFFAOYSA-N 0.000 description 1
- OEPOKWHJYJXUGD-UHFFFAOYSA-N 2-(3-phenylmethoxyphenyl)-1,3-thiazole-4-carbaldehyde Chemical compound O=CC1=CSC(C=2C=C(OCC=3C=CC=CC=3)C=CC=2)=N1 OEPOKWHJYJXUGD-UHFFFAOYSA-N 0.000 description 1
- PEFIQBVQMPKANX-UHFFFAOYSA-N 3-(1,3-dibutoxypropan-2-yloxymethyl)heptane Chemical compound CCCCOCC(COCCCC)OCC(CC)CCCC PEFIQBVQMPKANX-UHFFFAOYSA-N 0.000 description 1
- JWSYJZKEPKDXHA-UHFFFAOYSA-N 3-(2,5-dimethylhexan-2-yloxy)propane-1,2-diol Chemical compound C(C)(C)CCC(C)(C)OCC(O)CO JWSYJZKEPKDXHA-UHFFFAOYSA-N 0.000 description 1
- YHCCCMIWRBJYHG-UHFFFAOYSA-N 3-(2-ethylhexoxymethyl)heptane Chemical compound CCCCC(CC)COCC(CC)CCCC YHCCCMIWRBJYHG-UHFFFAOYSA-N 0.000 description 1
- DWYVJBPOMVHFKW-UHFFFAOYSA-N 3-(2-methyloctan-2-yloxy)propane-1,2-diol Chemical compound CCCCCCC(C)(C)OCC(O)CO DWYVJBPOMVHFKW-UHFFFAOYSA-N 0.000 description 1
- CBWPGKXHWQUERP-UHFFFAOYSA-N 3-(2-propan-2-yloxyethoxymethyl)heptane Chemical compound CCCCC(CC)COCCOC(C)C CBWPGKXHWQUERP-UHFFFAOYSA-N 0.000 description 1
- AEQSRSXWZJFUTF-UHFFFAOYSA-N 3-(20-methylhenicosan-5-yloxy)propane-1,2-diol Chemical compound OCC(O)COC(CCCC)CCCCCCCCCCCCCCC(C)C AEQSRSXWZJFUTF-UHFFFAOYSA-N 0.000 description 1
- GQQHEKOOHGFEED-UHFFFAOYSA-N 3-(propan-2-yloxymethyl)heptane Chemical compound CCCCC(CC)COC(C)C GQQHEKOOHGFEED-UHFFFAOYSA-N 0.000 description 1
- QRIIMZADASNLNI-UHFFFAOYSA-N 3-[2-(2-ethylhexoxy)ethoxymethyl]heptane Chemical compound CCCCC(CC)COCCOCC(CC)CCCC QRIIMZADASNLNI-UHFFFAOYSA-N 0.000 description 1
- NZXXOEAWMQEZPZ-UHFFFAOYSA-N 3-[2-(2-ethylhexoxy)propoxymethyl]heptane Chemical compound CCCCC(CC)COCC(C)OCC(CC)CCCC NZXXOEAWMQEZPZ-UHFFFAOYSA-N 0.000 description 1
- ZVEHYXJFLMJYKE-UHFFFAOYSA-N 3-[2-(2-propan-2-yloxyethoxy)ethoxymethyl]heptane Chemical compound CCCCC(CC)COCCOCCOC(C)C ZVEHYXJFLMJYKE-UHFFFAOYSA-N 0.000 description 1
- KDEPTIZYSPUNAD-UHFFFAOYSA-N 3-[2-[2-(2-ethylhexoxy)ethoxy]ethoxymethyl]heptane Chemical compound CCCCC(CC)COCCOCCOCC(CC)CCCC KDEPTIZYSPUNAD-UHFFFAOYSA-N 0.000 description 1
- QRIUEZQNQVVNQK-UHFFFAOYSA-N 3-methyl-1-[2-(2-propan-2-yloxyethoxy)ethoxy]butane Chemical compound CC(C)CCOCCOCCOC(C)C QRIUEZQNQVVNQK-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- AQZGPSLYZOOYQP-UHFFFAOYSA-N Diisoamyl ether Chemical compound CC(C)CCOCCC(C)C AQZGPSLYZOOYQP-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- QHIWVLPBUQWDMQ-UHFFFAOYSA-N butyl prop-2-enoate;methyl 2-methylprop-2-enoate;prop-2-enoic acid Chemical compound OC(=O)C=C.COC(=O)C(C)=C.CCCCOC(=O)C=C QHIWVLPBUQWDMQ-UHFFFAOYSA-N 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 229920006026 co-polymeric resin Polymers 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229920001483 poly(ethyl methacrylate) polymer Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920005990 polystyrene resin Polymers 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 229930195734 saturated hydrocarbon Natural products 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62263697A JPH01107771A (ja) | 1987-10-21 | 1987-10-21 | 医療用硬質樹脂組成物および医療用具 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62263697A JPH01107771A (ja) | 1987-10-21 | 1987-10-21 | 医療用硬質樹脂組成物および医療用具 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01107771A JPH01107771A (ja) | 1989-04-25 |
| JPH0242505B2 true JPH0242505B2 (enrdf_load_stackoverflow) | 1990-09-25 |
Family
ID=17393080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62263697A Granted JPH01107771A (ja) | 1987-10-21 | 1987-10-21 | 医療用硬質樹脂組成物および医療用具 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01107771A (enrdf_load_stackoverflow) |
-
1987
- 1987-10-21 JP JP62263697A patent/JPH01107771A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01107771A (ja) | 1989-04-25 |
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