JPH0222066B2 - - Google Patents

Info

Publication number
JPH0222066B2
JPH0222066B2 JP56126061A JP12606181A JPH0222066B2 JP H0222066 B2 JPH0222066 B2 JP H0222066B2 JP 56126061 A JP56126061 A JP 56126061A JP 12606181 A JP12606181 A JP 12606181A JP H0222066 B2 JPH0222066 B2 JP H0222066B2
Authority
JP
Japan
Prior art keywords
bis
group
triiodo
anilide
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56126061A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57145849A (en
Inventor
Pufuaifuaa Hainritsuhi
Supetsuku Ururitsuhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS57145849A publication Critical patent/JPS57145849A/ja
Publication of JPH0222066B2 publication Critical patent/JPH0222066B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP56126061A 1980-10-10 1981-08-13 Novel n-hydroxy-alkylated dicarboxylic acid-bis-(3,5-dicarbamoyl-2,4,6-triiodo- anilide), manufacture and contrast agent containing same Granted JPS57145849A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803038853 DE3038853A1 (de) 1980-10-10 1980-10-10 Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)

Publications (2)

Publication Number Publication Date
JPS57145849A JPS57145849A (en) 1982-09-09
JPH0222066B2 true JPH0222066B2 (en, 2012) 1990-05-17

Family

ID=6114382

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56126061A Granted JPS57145849A (en) 1980-10-10 1981-08-13 Novel n-hydroxy-alkylated dicarboxylic acid-bis-(3,5-dicarbamoyl-2,4,6-triiodo- anilide), manufacture and contrast agent containing same

Country Status (14)

Country Link
US (1) US4426371A (en, 2012)
EP (1) EP0049745B1 (en, 2012)
JP (1) JPS57145849A (en, 2012)
AT (1) ATE10488T1 (en, 2012)
AU (1) AU545934B2 (en, 2012)
CA (1) CA1186333A (en, 2012)
DE (2) DE3038853A1 (en, 2012)
DK (1) DK158468C (en, 2012)
ES (1) ES8205757A1 (en, 2012)
GR (1) GR75308B (en, 2012)
IE (1) IE51495B1 (en, 2012)
IL (1) IL63480A (en, 2012)
NO (1) NO154550C (en, 2012)
PH (1) PH18855A (en, 2012)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3364536D1 (en) * 1982-11-08 1986-08-21 Nyegaard & Co As X-ray contrast agents
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
FR2541272A1 (fr) * 1983-02-23 1984-08-24 Guerbet Sa Composes bromes et produits opacifiants en contenant
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
GB8906130D0 (en) * 1989-03-17 1989-05-04 Nycomed As Compositions
US5698739A (en) * 1989-07-05 1997-12-16 Schering Aktiengesellschaft Carboxamide non-ionic contrast media
US5191120A (en) * 1989-12-13 1993-03-02 Mallinckrodt Medical, Inc. Process for preparing nonionic X-ray contrast agents
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
WO1993010078A1 (es) * 1991-11-18 1993-05-27 Centro Investigacion Justesa Imagen S.A. Nuevos agentes yodados no ionicos de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen
JPH07501809A (ja) * 1991-12-03 1995-02-23 マリンクロッド・メディカル・インコーポレイテッド 非イオン性ｘ線造影剤組成物およびその製造方法
FR2687669B1 (fr) * 1992-02-24 1997-12-19 Guerbet Sa Composes utilisables dans des produits de contraste pour la radiographie.
WO1994005337A1 (en) * 1992-09-02 1994-03-17 Mallinckrodt Medical, Inc. Nonionic x-ray contrast agents, compositions and methods
WO1995026331A1 (es) * 1994-03-25 1995-10-05 Centro Investigacion Justesa Imagen, S.A. Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones farmaceuticas que los contienen
WO2002051301A2 (en) 2000-11-10 2002-07-04 Wm. Marsh Rice University Fullerene (c60)-based x-ray contrast agent for diagnostic imaging
CA2591942A1 (en) 2005-01-13 2006-07-20 Cinvention Ag Composite materials containing carbon nanoparticles
JP5340281B2 (ja) 2007-07-12 2013-11-13 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US20100221192A1 (en) 2007-10-12 2010-09-02 Duncan George Wynn Contrast agents
CN101821231A (zh) 2007-10-12 2010-09-01 通用电气医疗集团股份有限公司 对比剂
CN101820923A (zh) 2007-10-12 2010-09-01 通用电气医疗集团股份有限公司 对比剂
CN101820924A (zh) 2007-10-12 2010-09-01 通用电气医疗集团股份有限公司 造影剂
JP2011509943A (ja) * 2008-01-14 2011-03-31 マリンクロッド・インコーポレイテッド イオシメノールを調製するためのプロセス
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
WO2016079330A1 (en) 2014-11-21 2016-05-26 Technical University Of Denmark Gel formulations for local drug release
CN109475491B (zh) 2016-05-20 2022-06-24 丹麦技术大学 可触诊的标记物组合物
CA3143104A1 (en) 2019-06-12 2020-12-17 Technical University Of Denmark Dissacharide formulations for controlled drug release

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34927B1 (en) 1969-06-27 1975-10-01 Nyegaard & Co As Non-ionic iodinated x-ray contrast agents
US4021481A (en) 1969-06-27 1977-05-03 Nyegaard & Co. A/S Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups
DD104193A5 (en, 2012) * 1972-12-22 1974-03-05
CH608189A5 (en, 2012) * 1974-12-13 1978-12-29 Savac Ag
GB1491129A (en) 1975-06-04 1977-11-09 Guerbet Sa Iodo-benzene derivatives and an x-ray contrast medium containing them
GB1548594A (en) 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
CH626873A5 (en, 2012) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
US4230845A (en) 1978-08-31 1980-10-28 Mallinckrodt, Inc. Polyhydroxy-alkyl-3,5-disubstituted-2,4,6-triiodocarbanilates
DE2852094A1 (de) * 1978-11-30 1980-06-12 Schering Ag Neue roentgenkontrastmittel
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
DE2928417A1 (de) 1979-07-12 1981-01-29 Schering Ag Trijodierte basen
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono

Also Published As

Publication number Publication date
US4426371A (en) 1984-01-17
IE51495B1 (en) 1987-01-07
IL63480A0 (en) 1981-10-30
EP0049745A1 (de) 1982-04-21
DK158468B (da) 1990-05-21
NO154550B (no) 1986-07-07
AU545934B2 (en) 1985-08-08
ES504701A0 (es) 1982-08-16
IE811841L (en) 1982-05-10
NO812753L (no) 1982-04-13
ES8205757A1 (es) 1982-08-16
GR75308B (en, 2012) 1984-07-13
NO154550C (no) 1986-10-15
DE3167463D1 (en) 1985-01-10
EP0049745B1 (de) 1984-11-28
DK300281A (da) 1982-04-11
DE3038853A1 (de) 1982-05-27
DK158468C (da) 1990-10-08
ATE10488T1 (de) 1984-12-15
AU7397881A (en) 1982-04-22
PH18855A (en) 1985-10-21
JPS57145849A (en) 1982-09-09
IL63480A (en) 1984-03-30
CA1186333A (en) 1985-04-30

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